Results 71 to 80 of about 13,230 (236)

Inhibition of voltage-dependent K+ current in rabbit coronary arterial smooth muscle cells by the class Ic antiarrhythmic drug propafenone

Korean Journal of Physiology and Pharmacology, 2018
In this study, we demonstrated the inhibitory effect of the Class Ic antiarrhythmic agent propafenone on voltage-dependent K+ (Kv) channels using freshly isolated coronary artery smooth muscle cells from rabbits.
J. An, Hongliang Li, M. Seo, W. Park
semanticscholar   +1 more source

Superwide Left Atrial Circumferential Ablation for Persistent Atrial Fibrillation: A Randomized Controlled Trial

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 7, Page 1530-1537, July 2025.
ABSTRACT Background It remains to be answered whether further enlargement of the isolation area in the left atrium (LA) could produce better effectiveness than pulmonary vein antrum isolation (PVAI) for treatment of atrial fibrillation (AF). Aims To assess the effectiveness of superwide left atrial circumferential ablation (SWLACA) for treatment of ...
Yue Cao, Wei Du, Yalan Fei, Hao Yang, Meng Wang, Qingshan Dong, Xianjin Li, Shijie Li, Bing Han   +8 more
wiley   +1 more source

POSSIBLE PREDICTORS OF ATRIAL FIBRILLATION RECURRENCE IN LONG-TERM PROPHYLACTIC PROPAFENONE THERAPY

Рациональная фармакотерапия в кардиологии, 2015
Aim. To identify possible predictors of atrial fibrillation (AF) recurrence in 6-month prophylactic propafenone therapy. Material and methods. Patients (n=63; aged 52.2±12.6 years; 25.4% women) with frequent AF recurrences who restored sinus rhythm with ...
R. D. Kurbanov, N. U. Zakirov, Sh. K. Azizov, Kh. M. Raubzhanov   +3 more
doaj   +3 more sources

Propafenone and amiodarone efficacy in paroxysmal atrial fibrillation treatment

Российский кардиологический журнал, 2006
To assess antiarrhythmic efficacy of propafenone and amiodarone in paroxysmal atrial fibrillation (AF) treatment, 204 patients (125 males, 79 females, aged 57-72 years) with various stages of heart failure (HF) were examined.
N. N. Isakova, Yu. V. Kulakov, A. M. Kononova, O. P. Modnova, L. M. Moldovanova, O. A. Moldovanova   +5 more
doaj  

Arrhythmic risk in elderly patients candidates to transcatheter aortic valve replacement. predicative role of repolarization temporal dispersion [PDF]

, 2019
Degenerative aortic valve stenosis (AS) is associated to ventricular arrhythmias and sudden cardiac death, as well as mental stress in specific patients. In such a context, substrate, autonomic imbalance as well as repolarization dispersion abnormalities ...
Crapanzano, Davide, DI IORIO, Claudia, Fabietti, Marcella, Magri', Damiano, Mariani, MARCO VALERIO, Mastropietri, Fabiola, Moscucci, Federica, Parrotta, Ilaria, Piccirillo, Gianfranco, Sabatino, Teresa, Salvi, Nicolo', Vespignani, Giulia   +11 more
core   +1 more source

Morphometric‐Assisted Prediction of Developmental Toxicity Using Stem Cell‐Based Embryo Models in Microwells

Advanced Healthcare Materials, Volume 14, Issue 15, 10 June, 2025.
This proof‐of‐concept study involves high‐throughput teratogenicity screening of compounds using XEn/EpiCs, a 3D stem cell‐based embryo model, within microwells. The term ‘morphotoxicity’ is introduced to complement traditional cytotoxicity assays through automated feature extraction and machine‐learning‐assisted classification of morphologies.
Vinidhra Shankar, Athanasia Zoi Pappa, Clemens van Blitterswijk, Erik Vrij, Stefan Giselbrecht   +4 more
wiley   +1 more source

Propafenone in restoring sinus rhythm among patients with persistent atrial fibrillation. PROMETEY – an open, multicenter, pilot study performed in the Russian Federation (part II)

Кардиоваскулярная терапия и профилактика, 2005
Aim. To study efficacy and safety of propafenone (450 mg/d per os) in maintaining sinus rhythm among patients with persistent atrial fibrillation (AF). Material and methods.
I. G. Fomina, A. I. Tarzimanova, A. V. Vetluzhsky, A. A. Abramova   +3 more
doaj  

Endothelial function changes in paroxysmal atrial fibrillation and treatment with propafenone

Кардиоваскулярная терапия и профилактика, 2018
Aim. To evaluate the changes of endothelial function in arterial hypertension (AH) patients with paroxysmal atrial fibrillation (AF) in treatment with propafenone (Propanorm, PRO.MED.CS Praha a. s.) in comparison with bisoprolol.Material and methods.
V. I. Podzolkov, A. I. Tarzimanova
doaj   +1 more source

Short- and long-term experience in pulmonary vein segmental ostial ablation for paroxysmal atrial fibrillation* [PDF]

, 2006
Introduction: Segmental ostial pulmonary vein isolation (PVI) is considered a potentially curative therapeutic approach in the treatment of paroxysmal atrial fibrillation (PAF).
Aichinger, J, Janssen, J, Martinek, M, Nesser, H.J, Pürerfellner, H   +4 more
core   +1 more source

Subtle Structural Differences Trigger Inhibitory Activity of Propafenone Analogues at the Two Polyspecific ABC Transporters: P‐Glycoprotein (P‐gp) and Breast Cancer Resistance Protein (BCRP)

ChemMedChem, 2016
The transmembrane ABC transporters P‐glycoprotein (P‐gp) and breast cancer resistance protein (BCRP) are widely recognized for their role in cancer multidrug resistance and absorption and distribution of compounds.
T. Schwarz, F. Montanari, Anna Cseke, Katrin Wlcek, Lene Visvader, Sarah Palme, P. Chiba, K. Kuchler, E. Urban, G. Ecker   +9 more
semanticscholar   +1 more source