Results 71 to 80 of about 10,218 (198)

Propafenone efficacy and safety in restoring and maintaining sinus rhythm in patients with recurrent atrial fibrillation: results of the open, prospective placebo-controlled trial

Кардиоваскулярная терапия и профилактика, 2005
Aim. To study efficacy and safety of propafenone in restoring and maintaining sinus rhythm (SR), comparing to placebo, in patients with recurrent atrial fibrillation (AF). Material and methods. The study included 60 patients with recurrent AF.
I. G. Fomina, A. V. Vetlyzhsky, A. I. Tarzimanova, A. A. Abramova   +3 more
doaj  

Independent derivations of the axis of arrhythmia for predicting drug‐induced torsades de pointes

British Journal of Pharmacology, Volume 182, Issue 18, Page 4299-4313, September 2025.
Abstract Background and Purpose: Torsades de pointes is a potentially lethal ventricular arrhythmia that can be induced by many classes of drugs. The risk for a given drug depends upon the combination of cardiac ion channels that it targets. The axis of arrhythmia quantifies that risk. It is a conceptual line in the electrophysiology that describes the
Stewart Heitmann, Jamie I. Vandenberg, Adam P. Hill   +2 more
wiley   +1 more source

Brugada-type Electrocardiographic Pattern Induced by Fever [PDF]

, 2005
ST-segment elevation in Brugada syndrome is caused by a shift in the ionic current balance and the creation of a voltage gradient between the epicardium and the endocardium. This ionic mechanism have been shown to be temperature dependent. We describe a
Aras, Dursun, Deveci, Bulent, Geyik, Bilal, Ozeke, Ozcan, Selcuk, Timur   +4 more
core   +2 more sources

Flecainide exerts paradoxical effects on sodium currents and atrial arrhythmia in murine RyR2-P2328S hearts. [PDF]

, 2015
AIMS: Cardiac ryanodine receptor mutations are associated with catecholaminergic polymorphic ventricular tachycardia (CPVT), and some, including RyR2-P2328S, also predispose to atrial fibrillation.
Chandrasekharan, KH, Fraser, JA, Guzadhur, L, Huang, CL-H, Jafferji, DIG, King, JH, Matthews, HR, Salvage, SC   +7 more
core   +2 more sources

Propafenone in restoring sinus rhythm among patients with persistent atrial fibrillation. PROMETEY – an open, multicenter, pilot study performed in the Russian Federation

Кардиоваскулярная терапия и профилактика, 2005
Aim. To study efficacy and safety of propafenone (loading single dose of 600 mg per os) in treating atrial fibrillation (AF) paroxysms. Material and methods. The study included 233 patients with persistent AF, aged 31-62 (mean age 57.6 ± 2.8 years), from
I. G. Fomina, A. I. Tarzimanova, A. V. Vetluzhsky, A. A. Abramova   +3 more
doaj  

Long‐Term Follow‐Up of Inducible Bundle Branch Reentrant Ventricular Tachycardia in Patients Without Structural Heart Disease: Beyond the Electrophysiology Laboratory

Journal of Cardiovascular Electrophysiology, Volume 36, Issue 9, Page 2140-2150, September 2025.
ABSTRACT Background Bundle branch reentrant ventricular tachycardia (BBR‐VT) is a rare form of VT occurring in patients with structural heart disease (SHD). Rarely, it can also occur in the absence of SHD. Understanding its clinical and electrophysiologic (EP) properties and outcomes post‐catheter ablation (CA) is crucial. Objective We present a series
Muhieddine Omar Chokr, Haroldo Heitor Ribeiro Filho, Roberto Alvarez Coello, Rodrigo Melo Kulchetscki, Lucas Moura, Francisco Darrieux, Denise T. Hachul, Luciana Sacilotto, Tan C. Wu, Pedro M. Vandoni, Italo B. Souza, Pedro Linhares, Cristiano F. Pisani, Carina A. Hardy, Mauricio I. Scanavacca   +14 more
wiley   +1 more source

To Pace Or Not To Pace! – Prevention Of Atrial Fibrillation After Coronary Artery Bypass Surgery [PDF]

, 2005
Atrial fibrillation (AF) is a very undesirable, but unfortunately a common arrhythmia following coronary artery bypass graft (CABG) surgery, occurring in up to 40% of patients.
Vora, Amit
core   +2 more sources

Propafenone efficacy in paroxysmal atrial fibrillation

Российский кардиологический журнал, 2004
Efficacy and safety of class IС antiarrhythmic agent, propafenone, was investigated in patients with paroxysmal atrial fibrillation (PAF), after single-dose load and during long-term preventive treatment.
V. V. Skibitsky, E. A. Kudryashov, N. A. Spiropulos, A. M. Kramskaya, Z. T. Sokaeva   +4 more
doaj  

A case of lethal suicidal intoxication with propafenone and diazepam

Annals of Noninvasive Electrocardiology
Diazepam poisoning is a common emergency situation, but propafenone poisoning is relatively rare. We reported a case of propafenone poisoning combined with diazepam.
Shuangbing Yan, Ting Xin, Xiaojie Luo, Yu Wang, Bingwei Chen   +4 more
doaj   +1 more source

In silico Assessment of Pharmacotherapy for Human Atrial Patho-Electrophysiology Associated With hERG-Linked Short QT Syndrome

Frontiers in Physiology, 2019
Short QT syndrome variant 1 (SQT1) arises due to gain-of-function mutations to the human Ether-à-go-go-Related Gene (hERG), which encodes the α subunit of channels carrying rapid delayed rectifier potassium current, IKr.
Dominic G. Whittaker, Dominic G. Whittaker, Jules C. Hancox, Jules C. Hancox, Henggui Zhang, Henggui Zhang, Henggui Zhang, Henggui Zhang   +7 more
doaj   +1 more source