Results 121 to 130 of about 1,467 (158)

Synthesis and Properties of Cu(Benzoylacetone-ethanolamine) and Cu(Benzoylacetone-propanolamine)

Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry, 1991
Abstract The Schiff base resulting from benzoylacetone and ethanolamine or propanolamine has been used to form copper(II) complexes. Cu(benzoylacetone-ethanolamine) is tetrameric with a ferromagnetic ground state. Cu(benzoylacetone-propanolamine) is dimeric with overall antiferromagnetic interaction and a singlet ground state.
K. Hines, L. J. Theriot
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ChemInform Abstract: Synthesis of Propanolamine Derivatives and Study of Their Antiviral Activity.

ChemInform, 1987
AbstractThe propanolamine derivatives (III), (VI), and (IX) are prepared from the epoxides (I) or the amines (IV) and (VII) as shown in the reaction scheme.
L. M. M. STANKYAVICHENE, A. P. STANKYAVICHYUS, M. S. SAPRAGONENE, S. P. RISELIS, P. B. TERENT'EV, KH. S. AZHAMI, G. V. VLADYKO, L. V. KOROBCHENKO, E. I. BOREKO   +8 more
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Synthesis and beta-adrenergic antagonist activity of novel (3-cyanodihydropyridyl)propanolamines.

Drug design and discovery, 1992
The synthesis and beta-adrenergic antagonist activities of 1-(1-dihydropyridyl)-3-alkylamino-2-propanols (9-16) in which the aryloxy group of aryloxypropanolamines (1) is replaced by a 1-[2-t-(n-)butyl-3-cyano-1,2-dihydropyridyl] (9-12) or 1-[6-t-(n-)butyl-3-cyano-1,6-dihydropyridyl] (13-16) moiety is described.
D, Vo, M W, Wolowyk, E E, Knaus
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Synthesis of propanolamine side chain deuterated propranolol, propranolol‐diol and 4‐hydroxypropranol

Journal of Labelled Compounds and Radiopharmaceuticals, 1978
AbstractSyntheses of 1‐(isopropylamino)‐3‐(1‐naphthyloxy)‐2‐propanol‐1,1,2,3,3‐d5 (1), 3‐(1‐naphthyloxy)‐1,2‐propanediol‐1,1,2,3,3‐d5 (2) and 1‐(isopropylamino)‐3‐(4‐hydroxy‐1‐naphthyloxy)‐2‐propanol‐1,1,2,3,3‐d5 (3) from epichlorohydrin‐d5 are described. Treatment of epichlorohydrin‐d5 with 1‐naphthol, in the presence of a catalytic amount of pyridine,
Richard B. Walker, Wendel L. Nelson
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Vanillylamide-Based Propanolamine Derivative Displays α/β-Adrenoceptor Blocking and Vasodilating Properties

Journal of Cardiovascular Pharmacology, 2002
A propanolamine derivative with vanillylamide base, KMUP 880602, was first investigated under in vivo and in vitro conditions. IV KMUP 880602 (0.1, 0.5, 1.0, and 2.0 mg/kg) produced dose-dependent hypotensive and bradycardia responses in pentobarbital-anesthetized Wistar rats. KMUP 880602 also markedly inhibited both the tachycardia effects induced by (
Jwu-Lai, Yeh, Jiunn-Ren, Wu, Chaw-Chi, Chiu, Yea-Wen, Chen, Yi-Ching, Lo, Young-Tso, Lin, Chang-Jenq, Cheng, Ing-Jun, Chen   +7 more
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ChemInform Abstract: SYNTHESIS AND PHARMACOLOGICAL STUDY OF 3‐PHENYL‐2‐PROPANOLAMINES

Chemischer Informationsdienst, 1979
AbstractAus Benzylchlormethyl‐keton (I) und den Grignard‐Reagenzien (II) werden die entsprechenden Chloralkohole (IIIa)‐(IIId) dargestellt und mit den sek. Aminen (IV) zu den entsprechenden Aminoalkoholen (Va)‐(Vd) umgesetzt.
H. GALONS, J.‐F. GIRARDEAU, C. COMBET FARNOUX, M. MIOCQUE, C. DUPONT, J. WEPIERRE   +5 more
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New chiral and isomeric cyclopropyl ketoxime propanolamine derivatives with potent .beta.-adrenergic blocking properties

Journal of Medicinal Chemistry, 1985
The synthesis of R-(+) and S-(-) isomers of O-[3-tert-butylamino)-2-hydroxypropyl] cyclopropyl methyl ketone oxime (falintolol) is described. The syn and anti isomers of falintolol were obtained in two different ways from cyclopropyl methyl ketoxime or from falintolol.
M, Bouzoubaa, G, Leclerc, S, Rakhit, G, Andermann   +3 more
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β-Adrenoceptor agonists and antagonists: conformational analysis of the ethanolamine and propanolamine side-chain

Journal of Molecular Structure: THEOCHEM, 1993
Abstract The solid state conformations of the ethanolamine or propanolamine side-chain for a variety of β-adrenoceptor agonists and antagonists have been analysed and compared to those conformations determined in solution and theoretical gas states. For the arylethanolamine (AEA)-type compounds the ethanolamine side-chain conformations adopted in the
T.L. Nero, W.J. Louis, D. Iakovidis
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A first-principle study of CO2 binding by monoethanolamine and mono-n-propanolamine solutions

Chemical Physics, 2015
Abstract Monoethanolamine (MEA) and mono- n -propanolamine (MPA) molecules were investigated for CO 2 binding using Density Functional Theory. MPA was predicted to bind CO 2 better than MEA along the bimolecular and trimolecular pathways. The additional CH 2 in MPA provided additional polarization to reduce the electrostatic repulsion for the ...
Hsueh-Chien Li, Ming-Kang Tsai
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Synthesis and beta-adrenergic antagonist activity of heterocyclic propanolamines.

Drug design and discovery, 1993
The synthesis and beta-adrenergic antagonist activities of a group of 1-(heteroaryloxy)- and 1-(heteroaryl)-3-alkylamino-2-propanols is described. beta 1-Adrenolytic (atria) structure-activity correlations indicated that replacement of the 1-naphthyl moiety of propranolol by a 4-quinolyl- (10), 2-quinolyl- (24), or 2-pyrimidyl- (26) heterocyclic moiety
D, Vo, M W, Wolowyk, E E, Knaus
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