Results 171 to 180 of about 1,962 (207)

Pharmacokinetic Studies on Some Novel (2-Nitro-1-Imidazolyl) Propanolamine Radiosensitizers

1982
One area of current interest in radiosensitizer development is in the use of nitroimidazoles of a more polar nature than misonida-zole, combining the benefits of a shorter half-life, and thus reduced tissue exposure, which has been correlated with the neuropathy observed with misonidazole (1), while also minimising brain penetration through the blood ...
A. I. Minchinton, V.S. Randhawa, F.A. Stewart, Michael R.L. Stratford   +3 more
openaire   +2 more sources

β-Adrenoceptor agonists and antagonists: conformational analysis of the ethanolamine and propanolamine side-chain

Journal of Molecular Structure: THEOCHEM, 1993
Abstract The solid state conformations of the ethanolamine or propanolamine side-chain for a variety of β-adrenoceptor agonists and antagonists have been analysed and compared to those conformations determined in solution and theoretical gas states. For the arylethanolamine (AEA)-type compounds the ethanolamine side-chain conformations adopted in the
Dimitri Iakovidis, William J. Louis, Tracy L. Nero   +2 more
openaire   +2 more sources

Synthesis of carbon‐14 labeled (±)‐2‐methyl‐3,3‐diphenyl‐3‐propanolamine (2‐MDP)

Journal of Labelled Compounds and Radiopharmaceuticals, 1988
AbstractThe preparation of 14C labeled (±)‐2‐methyl‐3,3‐diphenyl‐3‐propanolamine (3) from [14C]‐carbonyl‐benzophenone is described.
Brian R. de Costa, Andrew Thurkauf, Kenner C. Rice, Arthur E. Jacobson   +3 more
openaire   +2 more sources

ChemInform Abstract: Synthesis and β‐Adrenoceptor Blocking Activity of Some Aryloxy‐ and Benzoyloxy‐propanolamines.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
A. K. Marwah, R. Kaushal, B. E. Rao, B. S. Trivedi, G. S. Rao, George P. Thomas, P. Marwah, R. K. Varma   +7 more
openaire   +2 more sources

ChemInform Abstract: Synthesis and β‐Adrenergic Activity of a Series of 3‐(Substituted‐ Benzylideneaminoxy)propanolamine Derivatives.

ChemInform, 1995
AbstractChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable via the “References” option.
Elisabetta Orlandini, Marco Macchia, A. Lapucci, Bruno Macchia, G. Ferni, Adriano Martinelli, Daniela Gentili, Mario Pinza, Susanna Nencetti   +8 more
openaire   +2 more sources

Phencyclidine-like behavioral effects of 2-methyl-3,3-diphenyl-3-propanolamine (2-MDP)

Pharmacology Biochemistry and Behavior, 1984
2-Methyl-3,3-diphenyl-3-propanolamine (2-MDP) produced effects in animals similar to those produced by the dissociative anesthetics such as phencyclidine (PCP). Specifically, it shared the discriminative stimulus properties of PCP in rats trained to discriminate PCP (1 mg/kg) from saline; at higher doses, it disrupted brightness discrimination and ...
Andrew H. Tang, R.A. Code, A.A. Cangelosi, Stanley R. Franklin   +3 more
openaire   +3 more sources

BETA‐ADRENERGIC BLOCKING AGENTS, NITROGEN HETEROARYL‐SUBSTITUTED 2‐PROPANOLAMINES AND ETHANOLAMINES

, 1974
Eine Reihe von Methylheterocyclen (I) wird in Form ihrer Lithiumderivate (II) mit den Aminoacetonitrilen (III) zu den Enaminen (IV) umgesetzt, die durch Hydrolyse, Reduktion mit Natriumborhydrid und hydrierende Debenzylierung in Propanolamine (VII ...
R. F. Meyer, C. D. Stratton, S. Hastings, R. M. Corey   +3 more
semanticscholar   +1 more source

Synthesis and beta-adrenergic activity of a series of 3-(substituted-benzylideneaminoxy)propanolamine derivatives.

Farmaco (Societa chimica italiana : 1989), 1995
In an attempt to change the beta-adrenergic properties of completely aliphatic 3-(methyleneaminoxy)propanolamine derivatives, from antagonist to agonist, while still retaining the beta 2-selectivity, we described, in a previous paper, the synthesis of a series of such derivatives possessing a hydroxy or methoxy group linked to the aliphatic substituent
GENTILI D, LAPUCCI, ANNALINA, MACCHIA B, MACCHIA, MARCO, MARTINELLI, ADRIANO, NENCETTI, SUSANNA, ORLANDINI, ELISABETTA, FERNI G, PINZA M.   +8 more
openaire   +2 more sources

Synthesis and study of the antiviral activity of propanolamine derivatives

Pharmaceutical Chemistry Journal, 1987
S. P. Riselis, G. V. Vladyko, M. S. Sapragonene, A. P. Stankyavichyus, L. V. Korobchenko, Kh. S. Azhami, E. I. Boreko, L. M. M. Stankyavichene, P. B. Terent'ev   +8 more
openaire   +2 more sources

The molecular structure of tri-n-propanolamine borate

Inorganic and Nuclear Chemistry Letters, 1973
Zenei Taira, Kenji Osaki
openaire   +2 more sources