Results 81 to 90 of about 131,451 (287)

Survival after Abdominoperineal and Sphincter-Preserving Resection in Nonmetastatic Rectal Cancer: A Population-Based Time-Trend and Propensity Score-Matched SEER Analysis

open access: yesGastroenterology Research and Practice, 2017
Background. Abdominoperineal resection (APR) has been associated with impaired survival in nonmetastatic rectal cancer patients. It is unclear whether this adverse outcome is due to the surgical procedure itself or is a consequence of tumor-related ...
Rene Warschkow   +4 more
doaj   +1 more source

Utilization of the propensity score method: an exploratory comparison of proxy-completed to self-completed responses in the Medicare Health Outcomes Survey

open access: yesHealth and Quality of Life Outcomes, 2003
Background This research examined the use of the propensity score method to compare proxy-completed responses to self-completed responses in the first three baseline cohorts of the Medicare Health Outcomes Survey, administered in 1998, 1999, and 2000 ...
Drachman David   +7 more
doaj   +1 more source

An overview of the objectives of and the approaches to propensity score analyses [PDF]

open access: yes, 2017
The assessment of treatment effects from observational studies may be biased with patients not randomly allocated to the experimental or control group. One way to overcome this conceptual shortcoming in the design of such studies is the use of propensity
Heinze, Georg, Jüni, Peter
core  

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Covariate adjusted nonparametric methods under propensity analysis

open access: yesFrontiers in Applied Mathematics and Statistics
Propensity score is one of the most commonly used score functions in adjusting for covariates effect in statistical inference. It is important to understand the impact with propensity score in case some of the prespecified covariates are severely ...
Jiabu Ye, Dejian Lai
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Safety, adherence and efficacy of PCSK9 inhibitors: a retrospective real-world study

open access: yesProceedings of Singapore Healthcare, 2022
Introduction PCSK9 inhibitors demonstrated their effectiveness in reducing low-density lipoprotein cholesterol (LDL-C) and cardiovascular events in landmark trials. It remains unclear whether the results can be translated to Asian populations. This study
Bee Ling Kelly Chng   +6 more
doaj   +1 more source

An Adjustment of Survey Data Using Propensity Score Weighting

open access: yesKodo Keiryogaku (The Japanese Journal of Behaviormetrics), 2007
This study proposes the adoption of a neural network as an alternative to logistic regression analysis, which is conventionally used to estimate the propensity score (Rosenbaum & Rubin, 1983). Moreover, covariates that are frequently obscured are presented.Considering the response pattern to a mail survey by random sampling as a criterion, we examined ...
Hideki TOYODA   +3 more
openaire   +2 more sources

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Using State Administrative Data to Measure Program Performance [PDF]

open access: yes, 2006
We use administrative data from Missouri to examine the sensitivity of earnings impact estimates for a job training program based on alternative nonexperimental methods.
Gorislavsky, Alexey   +2 more
core  

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