Results 111 to 120 of about 1,792,800 (248)
Comparative assessment of crystallographic and cryo‐EM models in the Protein Data Bank
FEBS Open Bio, EarlyView.Raw data obtained by X‐ray crystallography or cryo‐EM result in experimental maps, ultimately fitted by atomic models. Although the physical principles are different, the final results can be viewed, compared, and evaluated in the same way. With cryogenic electron microscopy (cryo‐EM) on track to surpass X‐ray crystallography as the preferred method ...
Alexander Wlodawer +7 more
wiley +1 more source
Distribution of propensity scores of the IHC CRC dataset.
Distribution of propensity scores of the IHC CRC dataset.
Michael H. Roehrl (6876992) +3 more
core +1 more source
FEBS Open Bio, EarlyView.In this study, a novel esterase from the thermoacidophilic archaeon Thermoplasma acidophilum was biochemically and structurally characterized. Our results demonstrate that Ta0887 is a highly thermostable esterase that preferentially hydrolyzes p‐nitrophenyl hexanoate and possesses an α‐helical cap domain that likely contributes to its substrate ...
Alejandro Delgado‐Rey +4 more
wiley +1 more source
, 2018 Sengwee Toh,1 Robert Wellman,2 R Yates Coley,2 Casie Horgan,1 Jessica Sturtevant,1 Erick Moyneur,3 Cheri Janning,4 Roy Pardee,2 Karen J Coleman,5 David Arterburn,2 Kathleen McTigue,6 Jane Anau,2 Andrea J Cook2 On behalf of the PCORnet Bariatric Study ...
Horgan C +12 more
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FEBS Open Bio, EarlyView.The two catalytic subunits of typhoid toxin dissociate from the holotoxin in the ER of an intoxicated cell, but only CdtB exits the ER to generate immunosuppressive effects. PltA is retained in the ER and sequestered from its cytosolic target, thus allowing the anti‐inflammatory effects of CdtB to promote intestinal colonization.
Maria C. Zabala‐Rodriguez +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.The neurokinin 1 receptor exists as full‐length (NK1L) and C‐terminally truncated (NK1S) splice variants. We show that NK1S heterodimerizes with NK1L, impairing Gαq coupling and Ca2+ mobilization while enhancing β‐arrestin1 recruitment. NK1S suppresses substance P‐driven gene expression and cell migration, revealing NK1S as an endogenous biased ...
Lan Phuong Nguyen +8 more
wiley +1 more source
Application of the Generalized Propensity Score. Evaluation of public contributions to Piedmont enterprises. [PDF]
In this article, we apply a generalization of the propensity score of Rosenbaum and Rubin (1983b). Techniques based on the propensity score have long been used for causal inference in observational studies for reducing bias caused by non-random treatment
Mattei, Alessandra, Bia, Michela
core
A chill intro to causal inference via propensity scores
, 2019 An accessible introduction to causal inference using propensity scores.
George Berry
core +2 more sources
Introduction to propensity scores.
, 2014 Although randomization provides a gold-standard method of assessing causal relationships, it is not always possible to randomly allocate exposures. Where exposures are not randomized, estimating exposure effects is complicated by confounding.
Williamson, Elizabeth J, Forbes, Andrew
core +1 more source