Results 91 to 100 of about 1,792,800 (248)
Chasing Balance and Other Recommendations for Improving Nonparametric Propensity Score Models
Journal of Causal Inference, 2017 In this article, we carefully examine two important implementation issues when estimating propensity scores using generalized boosted models (GBM), a promising machine learning technique.
Griffin Beth Ann +4 more
doaj +1 more source
Transcripts enriched in codons that trigger P‐site tRNA‐mediated mRNA decay possess stable mRNA
FEBS Open Bio, EarlyView.PTMD codons were first described by Mendel et al. as mediators of an mRNA decay pathway dependent on the human protein CNOT3, homologous to yeast Not5. Our findings confirm that PTMD codons destabilize transcripts; however, unlike in yeast, the human pathway specifically targets and slightly destabilizes primarily stable mRNAs.
Rodolfo Lopes Carneiro +1 more
wiley +1 more source
Compensatory education for disadvantaged Mexican students : an impact evaluation using propensity score matching [PDF]
The authors use propensity score matching to evaluate the effectiveness of CONAFE, a compensatory education program in Mexico, in improving student test scores and lowering repetition and failure rates.
Trevino, Jorge Moreno, Shapiro, Joseph
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Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy
FEBS Open Bio, EarlyView.This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan +11 more
wiley +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
Enhancing causal inference in population-based neuroimaging data in children and adolescents
Developmental Cognitive NeuroscienceRecent years have seen the increasing availability of large, population-based, longitudinal neuroimaging datasets, providing unprecedented capacity to examine brain-behavior relationships in the neurodevelopmental context.
Rachel Visontay +5 more
doaj +1 more source
A Boosting Algorithm for Estimating Generalized Propensity Scores with Continuous Treatments
Journal of Causal Inference, 2015 In this article, we study the causal inference problem with a continuous treatment variable using propensity score-based methods. For a continuous treatment, the generalized propensity score is defined as the conditional density of the treatment-level ...
Zhu Yeying +2 more
doaj +1 more source
Dealing with Limited Overlap in Estimation of Average Treatment Effects [PDF]
Estimation of average treatment effects under unconfounded or ignorable treatment assignment is often hampered by lack of overlap in the covariate distributions.
Richard K. Crump +3 more
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Evaluating the effect of γ‐oryzanol on MASLD pathology using a medaka fish model
FEBS Open Bio, EarlyView.This study explores a liver disease called MASLD, which is increasing worldwide and can lead to serious damage. Researchers used medaka fish instead of rodents to test a food compound, γ‐oryzanol. Fish fed this compound had less liver fat and healthier gut bacteria.
Yukako Ito +7 more
wiley +1 more source
Pragmatic and Observational ResearchTakuma Koinuma,1,2,* Manabu Akazawa1,* 1Department of Public Health and Epidemiology, Meiji Pharmaceutical University, Kiyose, Tokyo, Japan; 2Center for Experiential Pharmacy Practice, Faculty of Pharmacy, Tokyo University of Pharmacy and
Koinuma T, Akazawa M
doaj