Results 41 to 50 of about 16,916 (259)

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

open access: yesFEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

A Moment of Truth in Translating Proper Names in Naguib Mahfouz’ Trilogy from Arabic into English

open access: yes, 2012
This study tackles the translation of proper names in Naguib Mahfouz’s Trilogy from Arabic into English. A masterpiece of three volumes, namely, Palace Walk, Palace of Desire, and Sugar Street, was translated by Hutchins and Kenny (1990), Hutchins, Kenny
Rabadi, Raghd Al
core   +2 more sources

Phosphoinositides and inositol phosphates as molecular glues

open access: yesFEBS Letters, EarlyView.
Inositol phosphates (IPs) and phosphoinositides (PIPs) regulate diverse eukaryotic processes. Beyond recruiting signaling proteins or acting as structural cofactors, recent studies suggest they mediate protein–protein interactions as natural molecular glues.
Aleshia Seaton‐Terry   +9 more
wiley   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

open access: yesFEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee   +7 more
wiley   +1 more source

Modelling stem cell differentiation related processes—A practical overview for biologists

open access: yesFEBS Letters, EarlyView.
Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar   +4 more
wiley   +1 more source

On the Enrichment of the Bulgarian Anthroponymicon: Borrowings, Word-Formation, and Name Creativity

open access: yesВопросы ономастики
The Bulgarian anthroponymicon, as a multifaceted and dynamic system, is continually reshaped by both external and internal influences. This article draws on an extensive body of anthroponymic material sourced from archival and published records, as well ...
Irina Aleksandrovna Sedakova
doaj   +1 more source

ABL kinase‐dependent phosphorylation of SH proteins promotes their direct interaction with CRK family SH2 domains

open access: yesFEBS Letters, EarlyView.
CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens   +8 more
wiley   +1 more source

Proper names in Odpór na odpowiedź kwestyj (1579) by Erazm Gliczner. Form and function

open access: yes, 2022
WprowadzenieMonografia ma na celu ukazanie zależności pomiędzy gatunkiem tekstu (w tym przypadku prozą polemiczną) a sposobem wykorzystania onimów. Analizie poddano wszystkie nazwy osobowe oraz nazwy geograficzne zawarte w dziele Erazma Glicznera pt ...
Gozdek, Magdalena
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Особенности передачи испанских топонимов в русском языке

open access: yesPolilog: Studia Neofilologiczne, 2018
Peculiarities of transmission of Spanish toponyms in Russian literature The article deals with peculiarities of transmission of Spanish toponyms in Russian literature. As the title implies the article describes different types of transmission of proper
Ирина Вотякова   +1 more
doaj   +1 more source

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