Properdin - Open Access .click

The Journal of Immunology, 1991
Abstract An ELISA using antibody to properdin (P), followed by antibody to C3 to detect complexes of P with C3 (P-C3), detected low levels of P-C3 complexes in human serum and plasma samples. Incubating serum for 1 h at 37 degrees C increased the amount of P-C3 and diminished factor B hemolytic activity without altering total alternative
L Y, Whiteman, D B, Purkall, S, Ruddy
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Properdin in complement activation and tissue injury

Molecular Immunology, 2013
The plasma protein properdin is the only known positive regulator of complement activation. Although regarded as an initiator of the alternative pathway of complement activation at the time of its discovery more than a half century ago, the role and ...
Bo Nilsson, Wen-Chao Song
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Properdin is a trimer

Molecular Immunology, 1982
Abstract Physical measurements on native properdin suggest that this protein is a trimer of mol. wt 145,600–152,600 consisting of three apparently identical subunits of mol. wt 49, 100 each.
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Methods for the Assay of Properdin

Vox Sanguinis, 1958
SummaryMethods proposed for the determination of properdin are described and evaluated. Preference is given to a modification of the zymosan assay of Pillemer. The properties of zymosan are investigated with the purpose of providing information on the nature of the groups which are responsible for the properdin interactions.In a second part a detailed ...
H C, ISLIKER, E, LINDER
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complement
alternative pathway
complement system

medicine
phagocytosis
factor h

inflammation
mouse model
repair