Results 81 to 90 of about 16,754,236 (393)
Ion channel function of polycystin‐2/polycystin‐1 heteromer revealed by structure‐guided mutagenesis
FEBS Letters, EarlyView.Mutations in polycystin‐1 (PC1) or polycystin‐2 (PC2) cause autosomal‐dominant polycystic kidney disease (ADPKD). We generated a novel gain‐of‐function PC2/PC1 heteromeric ion channel by mutating pore‐blocking residues. Moreover, we demonstrated that PC2 will preferentially assemble with PC1 to form heteromeric complexes when PC1 is co‐expressed ...
Tobias Staudner +7 more
wiley +1 more source
Accelerating materials property predictions using machine learning
Scientific Reports, 2013 The materials discovery process can be significantly expedited and simplified if we can learn effectively from available knowledge and data. In the present contribution, we show that efficient and accurate prediction of a diverse set of properties of ...
G. Pilania +4 more
semanticscholar +1 more source
Australian intellectual property report 2013 [PDF]
This report provides a collation of data and information about the IP system in Australia, where Australia sits in the global IP system, and how it measures up against other countries.
Intellectual Property (IP) Australia
core +2 more sources
Autophagy in cancer and protein conformational disorders
FEBS Letters, EarlyView.Autophagy plays a crucial role in numerous biological processes, including protein and organelle quality control, development, immunity, and metabolism. Hence, dysregulation or mutations in autophagy‐related genes have been implicated in a wide range of human diseases.
Sergio Attanasio
wiley +1 more source
, 2017 This Article confronts the conceptualist/non-conceptualist divide in property theory. Specifically, the Article addresses the primary normative objection to the conceptualist account of property.
Meredith M. Render
semanticscholar +1 more source
Sacks Forcing and the Shrink Wrapping Property
, 2019 We consider a property stronger than the Sacks property, called the shrink wrapping property, which holds between the ground model and each Sacks forcing extension.
González, Osvaldo Guzmán +1 more
core +1 more source
FEBS Letters, EarlyView.The protonated form of butyrate, as well as other short‐chain fatty acids (SCFAs), is membrane permeable. In acidic extracellular environments, this can lead to intracellular accumulation of SCFAs and cytosolic acidification. This phenomenon will be particularly relevant in acidic environments such as the large intestine or tumor microenvironments ...
Muwei Jiang +2 more
wiley +1 more source
Property Tax Limitations [PDF]
, 2008 This report discusses property tax limitations in the U.S. and highlights limitations imposed in Georgia.
John V. Winters
core
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Is there a “case for property” all the time? [PDF]
, 2002 The “case for property” in the mixed-asset portfolio is a topic of continuing interest to practitioners and academics. Such an analysis typically is performed over a fixed period of time and the optimum allocation to property inferred from the weight ...
Lee, Stephen
core