Results 81 to 90 of about 9,320,870 (342)

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Synthesis of Network Graph-analytic Reports of Guard and Support of Dynamic Search Processes and Systems

Безопасность информационных технологий, 2015
Methods and models of graph-analytic synthesis of network reports of protection and support of essentially nonlinear dynamic search processes and systems are considered.
Sergey Pavlovich Botuz, Veronika Sergevna Tsiganova   +1 more
doaj  

Technological Monitoring Applied to Survey-Based on Brazilian Patent Applications about PEMFC

Journal of Technology Management & Innovation, 2011
The present study aims to show the importance of patents as an instrument of technological innovation and to assess the relevance of technology of PEMFC in Brazil by means of the technological monitoring methodology from 1996 to 2005.
Deysimar de Souza Carvalho, Eduardo Winter, Cheila Gonçalves Mothé, Tatiana Carestiato da Silva   +3 more
doaj   +1 more source

Peptide‐based ligand antagonists block a Vibrio cholerae adhesin

FEBS Letters, EarlyView.
The structure of a peptide‐binding domain of the Vibrio cholerae adhesin FrhA was solved by X‐ray crystallography, revealing how the inhibitory peptide AGYTD binds tightly at its Ca2+‐coordinated pocket. Structure‐guided design incorporating D‐amino acids enhanced binding affinity, providing a foundation for developing anti‐adhesion therapeutics ...
Mingyu Wang, Grace Du, Charity Yongo‐Luwawa, Angelina Lu, Brett Kinrade, Kim Munro, Karl E. Klose, William D. Lubell, Peter Davies, Shuaiqi Guo   +9 more
wiley   +1 more source

Mapping unobserved coopetitions between shopping malls using mobile geolocation data

Regional Studies, Regional Science
This study challenges the conventional retail catchment analysis, which typically asserts that proximity is the primary driver of shopping mall patronage.
Yihan Guan, Chung Yim Yiu, Ka Shing Cheung   +2 more
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

FEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani, Noemi E. Nwosu, Viktoria Gocke, Müge Kasanmascheff, Hannes Mutschler   +4 more
wiley   +1 more source

Australian intellectual property report 2013 [PDF]

This report provides a collation of data and information about the IP system in Australia, where Australia sits in the global IP system, and how it measures up against other countries.
Intellectual Property (IP) Australia
core   +2 more sources

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Patent Applications on Representative Sectors of Biotechnology in Brazil: an Analysis of the Last Decade

Journal of Technology Management & Innovation, 2013
The present article aims to assess the innovative activity in the Brazilian most representative sector in biotechnology field. The search was conducted through patent applications of residents at the National Institute of Industrial Property (INPI ...
Liliana Machado Mendes, Beatriz Amorim-Borher, Celso Lage   +2 more
doaj   +1 more source