Results 31 to 40 of about 13,992 (159)

May the Phage be With You? Prophage-Like Elements in the Genomes of Soft Rot Pectobacteriaceae: Pectobacterium spp. and Dickeya spp.

Frontiers in Microbiology, 2019
Soft Rot Pectobacteriaceae (SRP; Pectobacterium spp. and Dickeya spp., formerly known as pectinolytic Erwinia spp.) are necrotrophic bacterial pathogens infecting a large number of plant species worldwide, including agriculturally-important crops ...
Robert Czajkowski
doaj   +1 more source

Evolution along the parasitism-mutualism continuum determines the genetic repertoire of prophages.

PLoS Computational Biology, 2020
Integrated into their bacterial hosts' genomes, prophage sequences exhibit a wide diversity of length and gene content, from highly degraded cryptic sequences to intact, functional prophages that retain a full complement of lytic-function genes. We apply
Amjad Khan, Alita R Burmeister, Lindi M Wahl   +2 more
doaj   +1 more source

Presence and Persistence of Putative Lytic and Temperate Bacteriophages in Vaginal Metagenomes from South African Adolescents

Viruses, 2021
The interaction between gut bacterial and viral microbiota is thought to be important in human health. While fluctuations in female genital tract (FGT) bacterial microbiota similarly determine sexual health, little is known about the presence ...
Anna-Ursula Happel, Christina Balle, Brandon S. Maust, Iyaloo N. Konstantinus, Katherine Gill, Linda-Gail Bekker, Rémy Froissart, Jo-Ann Passmore, Ulas Karaoz, Arvind Varsani, Heather Jaspan   +10 more
doaj   +1 more source

The Defective Prophage Pool of Escherichia coli O157: Prophage–Prophage Interactions Potentiate Horizontal Transfer of Virulence Determinants

PLoS Pathogens, 2009
Bacteriophages are major genetic factors promoting horizontal gene transfer (HGT) between bacteria. Their roles in dynamic bacterial genome evolution have been increasingly highlighted by the fact that many sequenced bacterial genomes contain multiple prophages carrying a wide range of genes. Enterohemorrhagic Escherichia coli O157 is the most striking
Md Asadulghani, Yoshitoshi Ogura, Tadasuke Ooka, Takehiko Itoh, Akira Sawaguchi, Atsushi Iguchi, Keisuke Nakayama, Tetsuya Hayashi   +7 more
openaire   +4 more sources

Comparative Genomic Analysis of a Multidrug-Resistant Staphylococcus hominis ShoR14 Clinical Isolate from Terengganu, Malaysia, Led to the Discovery of Novel Mobile Genetic Elements

Pathogens, 2022
Staphylococcus hominis is a coagulase-negative Staphylococcus (CoNS) commensal capable of causing serious systemic infections in humans. The emergence of multidrug-resistant S.
Esra’a I. Al-Trad, Ainal Mardziah Che Hamzah, Suat Moi Puah, Kek Heng Chua, Stephen M. Kwong, Chew Chieng Yeo, Ching Hoong Chew   +6 more
doaj   +1 more source

Prophage Finder: A Prophage Loci Prediction Tool for Prokaryotic Genome Sequences

In Silico Biology: Journal of Biological Systems Modeling and Multi-Scale Simulation, 2006
Prophage loci often remain under-annotated or even unrecognized in prokaryotic genome sequencing projects. A PHP application, Prophage Finder, has been developed and implemented to predict prophage loci, based upon clusters of phage-related gene products encoded within DNA sequences.
M, Bose, Robert D, Barber
openaire   +2 more sources

Ecology of prophage-like elements in Bacillus subtilis at global and local geographical scales

Cell Reports
Summary: Prophages constitute a substantial portion of bacterial genomes, yet their effects on hosts remain poorly understood. We examine the abundance, distribution, and activity of prophages in Bacillus subtilis using computational and laboratory ...
Polonca Stefanic, Eva Stare, Valentina A. Floccari, Jasna Kovac, Robert Hertel, Ulisses Rocha, Ákos T. Kovács, Ines Mandić-Mulec, Mikael Lenz Strube, Anna Dragoš   +9 more
doaj   +1 more source

Diverse Prophage Elements of Salmonella enterica Serovars Show Potential Roles in Bacterial Pathogenicity

Cells
Nontyphoidal salmonellosis is an important foodborne and zoonotic infection that causes significant global public health concern. Diverse serovars are multidrug-resistant and encode several virulence indicators; however, little is known on the role ...
Kirstie Andrews, Toby Landeryou, Thomas Sicheritz-Pontén, Janet Yakubu Nale   +3 more
doaj   +1 more source

Characterization of Clinical and Carrier Streptococcus agalactiae and Prophage Contribution to the Strain Variability

Viruses, 2020
Streptococcus agalactiae (group B Streptococcus, GBS) represents a leading cause of invasive bacterial infections in newborns and is also responsible for diseases in older and immunocompromised adults. Prophages represent an important factor contributing
Aneta Lichvariková, Katarina Soltys, Tomas Szemes, Livia Slobodnikova, Gabriela Bukovska, Jan Turna, Hana Drahovska   +6 more
doaj   +1 more source

Programmable Klebsiella pneumoniae Phage Tropism Enabled by Scalable Receptor‐Binding Protein Mining and Modular Assembly

Advanced Science, EarlyView.
This work introduces a scalable, data‐driven strategy that turns the vast sequence diversity of phage receptor‐binding proteins into modular tools for engineering customizable phages. By clustering and experimentally validating diverse RBPs, the authors build an accurate map linking sequence to host specificity and create plug‐and‐play modules that ...
Shisong Jing, Yiyao Song, Xianbiao Bi, Yuqin Song, Dawei Wei, Jiangqing Huang, Yuan Zeng, Gang Zhang, Rong Zhang, Chao Wang, Jie Feng   +10 more
wiley   +1 more source