Results 31 to 40 of about 98,759 (204)
Efficient and Flexible Synthesis of New Photoactivatable Propofol Analogs [PDF]
Propofol is a widely used general anesthetic, which acts by binding to and modulating several neuronal ion channels. We describe the synthesis of photoactivatable propofol analogs functionalized with an alkyne handle for bioorthogonal chemistry.
Joseph, Wzorek +3 more
core +1 more source
Propofol Anesthesia Impairs the Maturation and Survival of Adult-born Hippocampal Neurons [PDF]
BACKGROUND:: Adult neurogenesis occurs in the hippocampus of most mammals, including humans, and plays an important role in hippocampal-dependent learning. This process is highly regulated by neuronal activity and might therefore be vulnerable to
Krzisch, M. +11 more
core +1 more source
Summary Ninety patients scheduled to undergo minor gynaecological surgery were divided into three groups. Group 1 received propofol only, for both induction and maintenance of anaesthesia. Group 2 were given propofol for induction and maintenance but inhaled 66% nitrous oxide in addition.
R D, Gunawardene, D C, White
openaire +2 more sources
Propofol-induced priapism in a 25-year-old male confirmed by rechallenge is reported for its rarity and to create awareness among practitioners, because propofol is used frequently in India for the induction and maintenance of anesthesia or sedation. The probable mechanisms are highlighted.
Senthilkumaran, Subramanian +4 more
openaire +3 more sources
Aim: This retrospective observational study evaluates the safety and efficacy of intravenous sedation using midazolam only or combinations of two or three drugs including propofol and alfentanil for complex dental surgery such as implant placement or ...
Kingsford, NM +4 more
core +1 more source
Sensitivity to propofol in the elderly [PDF]
Summary Two studies were carried out on 609 fit, unpremedicated patients to assess the influence of patient age on the response to the rapidly‐acting hindered phenol, propofol, which is being evaluated for induction of anaesthesia.
J W, Dundee +3 more
openaire +2 more sources
Safety and side effects of propofol in clinical practice - literature overview
Introduction and purpose Since people have been conducting surgeries to improve their health, they have always faced the problem of pain that these actions inevitably bring. Propofol as an anesetic is one of the solutions to these problems. Due to the
Maciej Lambach +9 more
doaj +1 more source
Effects of propofol in lipid-based emulsion and in microemulsion on the incidence of endothelial lesion in rabbits [PDF]
PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME).
Cristian Durço Paço +8 more
doaj
Estudo comparativo do propofol com o midazolam para a sedação, a curto prazo, de pacientes sob ventilação mecanica internada em UTI [PDF]
Dissertação (Mestrado) - Universidade Federal de Santa Catarina, Centro de Ciencias da SaudeFoi realizado um estudo clínico aberto, controlado e randomizado em 30 pacientes adultos, com o objetivo de comparar a segurança e a eficácia do propofol a do ...
Moritz, Rachel Duarte
core
Target-controlled infusion of propofol in dogs - Evaluation of four targets for induction of anaesthesia [PDF]
Four groups of 20 dogs were anaesthetised by means of target-controlled infusions of propofol designed to achieve 2.5 μg/ml, 3.0 μg/m., 3.5 μg/ml or 4.0 μg/ml of propofol in blood.
Musk, G.C.
core

