Results 31 to 40 of about 69,815 (159)

Association of Polymorphisms in Pharmacogenetic Candidate Genes with Propofol Susceptibility

Scientific Reports, 2017
Significant individual susceptibility to intravenous anesthetic propofol exists. The etiology of individual variability in the response to propofol may be influenced by genetic polymorphisms in metabolic and functional pathways.
Qi Zhong, Xiangdong Chen, Yan Zhao, Ru Liu, Shanglong Yao   +4 more
doaj   +1 more source

Propofol induces nuclear localization of Nrf2 under conditions of oxidative stress in cardiac H9c2 cells. [PDF]

PLoS ONE, 2018
Oxidative stress contributes to myocardial ischemia-reperfusion injury, which causes cardiomyocyte death and precipitate life-threatening heart failure. Propofol has been proposed to protect cells or tissues against oxidative stress.
Takeaki Shinjo, Tatsuhide Tanaka, Hiroaki Okuda, Akira T Kawaguchi, Kentaro Oh-Hashi, Yuki Terada, Ayami Isonishi, Shoko Morita-Takemura, Kouko Tatsumi, Masahiko Kawaguchi, Akio Wanaka   +10 more
doaj   +1 more source

Sensitivity to propofol in the elderly [PDF]

Anaesthesia, 1986
Summary Two studies were carried out on 609 fit, unpremedicated patients to assess the influence of patient age on the response to the rapidly‐acting hindered phenol, propofol, which is being evaluated for induction of anaesthesia.
J W, Dundee, F P, Robinson, J S, McCollum, C C, Patterson   +3 more
openaire   +2 more sources

Effects of different rates of propofol with or without S-ketamine on ventricular function in healthy cats – a randomized study

Frontiers in Veterinary Science, 2023
Propofol is used for anesthetic induction in cats and procedural sedation in countries where alfaxalone is not available. Studies have reported propofol-related effects in echocardiography variables in dogs and humans.
Sabrine Marangoni, Matheus Ubiali, Francieli Ambrosini, Larissa Jahnel, Julia M. Vilani, Paulo V. Steagall, Paulo V. Steagall, Ricardo Guilherme D’Otaviano de Castro Vilani   +7 more
doaj   +1 more source

Central depressant effects and toxicity of propofol in chicks

Toxicology Reports, 2014
Propofol is an ultra-short acting anesthetic agent. The information on the pharmacological and toxicological effects of propofol in the chicken is rather limited.
A.S. Naser, F.K. Mohammad
doaj   +1 more source

Disturbance of Key Cellular Subproteomes upon Propofol Treatment Is Associated with Increased Permeability of the Blood-Brain Barrier

Proteomes, 2022
Background: Propofol is a short-acting anesthetic, which is often used for induction and maintenance of general anesthesia, sedation for mechanically ventilated adults and procedural sedation.
Timo Längrich, Kaya Bork, Rüdiger Horstkorte, Veronika Weber, Britt Hofmann, Matt Fuszard, Heidi Olzscha   +6 more
doaj   +1 more source

Effects of propofol in lipid-based emulsion and in microemulsion on the incidence of endothelial lesion in rabbits [PDF]

Acta Cirúrgica Brasileira, 2013
PURPOSE: To compare the incidence of endothelial injury after single-dose or continuous propofol infusion in conventional lipid-based emulsion (LE) versus microemulsion (ME).
Cristian Durço Paço, Matheus Fachini Vane, Rafael Bicarato de Andrade, Maria Aparecida Domingues, Lidia Raquel de Carvalho, Daniela Carvalho dos Santos, Regina Kiomi Takahira, Norma Sueli Pinheiro Modolo, Luiz Antonio Vane   +8 more
doaj  

Safety and side effects of propofol in clinical practice - literature overview

Journal of Education, Health and Sport, 2023
Introduction and purpose Since people have been conducting surgeries to improve their health, they have always faced the problem of pain that these actions inevitably bring. Propofol as an anesetic is one of the solutions to these problems. Due to the
Maciej Lambach, Gabriela Demidowicz, Natalia Trąbka, Klaudia Kowalczyk, Nina Lasota, Wojciech Wiśniewski, Małgorzata Chyćko, Julia Czarnota, Katarzyna Cichoń, Martyna Younes   +9 more
doaj   +1 more source

Incidence of tolerance in children undergoing repeated administration of propofol for proton radiation therapy: a retrospective study

BMC Anesthesiology, 2018
Background Propofol is an excellent hypnotic drug for use in repeated radiation procedures in young children. To date, tolerance to propofol generally does not develop in pediatric patients undergoing radiation therapy.
RyungA Kang, Byung Seop Shin, Young Hee Shin, Nam-Su Gil, Ye Na Oh, Ji Seon Jeong   +5 more
doaj   +1 more source

Descriptive Analysis of the Relationship Between Continuous Intravenous Insulin Infusion and Triglyceride Levels in Critically Ill Patients Receiving Propofol Infusion

Anesthesia Research
Background/Objectives: Propofol is a preferred agent for ICU sedation. Hypertriglyceridemia occurs in up to 45% of patients on propofol and has been linked with adverse effects.
Sarah R. Peppard, Jayshil J. Patel
doaj   +1 more source