Results 41 to 50 of about 98,759 (204)

Propofol Infusion Syndrome

, 2011
Propofol Infusion Syndrome (PRIS) is a fatal clinical manifestation that is considered to be associated with usage of long time and high doses of propofol infusions.
Şule Akın
core   +1 more source

Incidence of tolerance in children undergoing repeated administration of propofol for proton radiation therapy: a retrospective study

BMC Anesthesiology, 2018
Background Propofol is an excellent hypnotic drug for use in repeated radiation procedures in young children. To date, tolerance to propofol generally does not develop in pediatric patients undergoing radiation therapy.
RyungA Kang, Byung Seop Shin, Young Hee Shin, Nam-Su Gil, Ye Na Oh, Ji Seon Jeong   +5 more
doaj   +1 more source

NMR Study of the Association of Propofol with Nonionic Surfactants [PDF]

, 2003
The general anesthetic 2,6-diisopropylphenol (propofol) is very poorly soluble in water and is normally administered in the form of an emulsion. We demonstrated that several commercially available nonionic surfactants (Tween 80, Cremophor EL, Poloxamer ...
Deo, Peter, Momot, Konstantin I., Whittaker, Darryl, Chapman, Bogdan E., Kuchel, Philip W.   +4 more
core   +1 more source

Propofol suppresses migration and vascular mimicry of breast cancer MCF-7 cells by down regulating interleukin-6

Pakistan Journal of Pharmaceutical Sciences
Propofol is widely used in anesthesia, but its role in breast cancer progression remains controversial. This study investigated the molecular mechanisms of propofol in breast cancer, focusing on IL-6 and tumor microenvironment modulation.
Shi-Yi Tian, Ming-Qing Peng, Min Li
doaj   +1 more source

The Impact of Age on Propofol Requirement for Inducing Loss of Consciousness in Elderly Surgical Patients

Frontiers in Pharmacology, 2022
It is generally accepted that geriatric patients are more sensitive to propofol than adults; thus, a dose-adjusted propofol is recommended for these patients during the induction of anesthesia.
Hua Yang, Hui-Min Deng, Hai-Yan Chen, Shu-Heng Tang, Fang Deng, Yu-Gang Lu, Jin-Chao Song   +6 more
doaj   +1 more source

The Growth of Microorganisms in Propofol and Mixtures of Propofol and Lidocaine

Survey of Anesthesiology, 1999
Propofol emulsion supports bacterial growth. Extrinsic contamination of propofol has been implicated as an etiological event in postsurgical infections. When added to propofol, local anesthetics (e.g., lidocaine) alleviate the pain associated with injecting it. Because local anesthetics have antimicrobial activity, we determined whether lidocaine would
I, Wachowski, D T, Jolly, J, Hrazdil, J C, Galbraith, M, Greacen, A S, Clanachan   +5 more
openaire   +3 more sources

Dexmedetomidine vs Propofol as an Adjunct to Ketamine for Electroconvulsive Therapy Anaesthesia

, 2022
OBJECTIVE: Electroconvulsive therapy is an effective non-pharmacological treatment for refractory mental illness, where a generalized seizure is induced under general anaesthesia.
Türeci, Ercan, Yeter, Tuğçe, Tuğçe Yeter, Onur Gönen, Aybike, Aybike Onur Gönen, Ercan Türeci   +5 more
core   +1 more source

Descriptive Analysis of the Relationship Between Continuous Intravenous Insulin Infusion and Triglyceride Levels in Critically Ill Patients Receiving Propofol Infusion

Anesthesia Research
Background/Objectives: Propofol is a preferred agent for ICU sedation. Hypertriglyceridemia occurs in up to 45% of patients on propofol and has been linked with adverse effects.
Sarah R. Peppard, Jayshil J. Patel
doaj   +1 more source

Propofol inhibits proliferation and epithelial-mesenchymal transition of MCF-7 cells by suppressing miR-21 expression

Artificial Cells, Nanomedicine, and Biotechnology, 2019
Breast cancer is a common malignant tumor with a high incidence of recurrence and metastasis. It has been reported that propofol has certain anti-breast cancer effects, but the intrinsic molecular mechanism remains unclear.
Qing Du, Xuezhi Zhang, Xin Zhang, Ming Wei, Hongmei Xu, Shilei Wang   +5 more
doaj   +1 more source

The effects of repeated propofol anesthesia on spatial memory and long-term potentiation in infant rats under hypoxic conditions

Genes and Diseases, 2020
Propofol is widely used as an intravenous drug for induction and maintenance in general anesthesia. Hypoxemia is a common complication during perianesthesia.
Mang Sun, Ruixue Yuan, Hui Liu, Jing Zhang, Shengfen Tu   +4 more
doaj   +1 more source