Results 51 to 60 of about 89,583 (305)

Descriptive Analysis of the Relationship Between Continuous Intravenous Insulin Infusion and Triglyceride Levels in Critically Ill Patients Receiving Propofol Infusion

open access: yesAnesthesia Research
Background/Objectives: Propofol is a preferred agent for ICU sedation. Hypertriglyceridemia occurs in up to 45% of patients on propofol and has been linked with adverse effects.
Sarah R. Peppard, Jayshil J. Patel
doaj   +1 more source

Physiologically‐based pharmacokinetic modelling of uridine 5′‐diphosphoglucorosultransferase (UGT) substrate drugs in pregnant women

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aims While pregnancy‐related changes in phase I enzyme activity are well‐documented, less is known about the impact on phase II enzymes. This study aimed to test the hypothesis that changes in the pharmacokinetics (PK) of uridine 5′‐diphosphoglucuronosyltransferase (UGT) substrates during pregnancy result from altered enzyme expression or activity ...
William Saffaf   +6 more
wiley   +1 more source

Development of Propofol-Encapsulated Liposomes and the Effect of Intranasal Administration on Bioavailability in Rabbits

open access: yesPharmaceutics
Background/Objectives: Propofol is frequently used as an intravenous anesthetic and is rapidly metabolized. Therefore, if it could be administered non-invasively (e.g., orally) as premedication, it might hasten emergence from anesthesia, thereby ...
Hitomi Ujita   +5 more
doaj   +1 more source

Propofol inhibits proliferation and metastasis by up-regulation of miR-495 in JEG-3 choriocarcinoma cells

open access: yesArtificial Cells, Nanomedicine, and Biotechnology, 2019
Choriocarcinoma is a rare gestational trophoblastic tumour. Propofol is one of the commonly used intravenous anaesthetic agents and exerts an anti-tumour role in multiple cancers.
Hai Sun, Yingjian Wang, Wenyu Zhang
doaj   +1 more source

The influence of storage time and temperature on propofol concentrations in canine blood and plasma [PDF]

open access: yesPeerJ, 2017
Propofol is an intravenous anesthetic commonly used due to its favorable pharmacokinetic and pharmacodynamic profile. There are discrepancies in the literature about the most appropriate sample for determining propofol concentrations. Although plasma has
Sherry Cox   +4 more
doaj   +2 more sources

The Impact of Age on Propofol Requirement for Inducing Loss of Consciousness in Elderly Surgical Patients

open access: yesFrontiers in Pharmacology, 2022
It is generally accepted that geriatric patients are more sensitive to propofol than adults; thus, a dose-adjusted propofol is recommended for these patients during the induction of anesthesia.
Hua Yang   +6 more
doaj   +1 more source

The Growth of Microorganisms in Propofol and Mixtures of Propofol and Lidocaine

open access: yesSurvey of Anesthesiology, 1999
Propofol emulsion supports bacterial growth. Extrinsic contamination of propofol has been implicated as an etiological event in postsurgical infections. When added to propofol, local anesthetics (e.g., lidocaine) alleviate the pain associated with injecting it. Because local anesthetics have antimicrobial activity, we determined whether lidocaine would
I, Wachowski   +5 more
openaire   +3 more sources

Impact of age and effect site concentrations of propofol on adverse events during general anesthesia

open access: yes, 2022
openIntroduzione L’anestesia generale somministrata totalmente per via endovenosa associata a Target Controlled Infusion (TIVA-TCI) è una tecnica innovativa e in rapida diffusione nel campo anestesiologico.
DE PICCOLI, SARA
core  

Nanophotonic Biosensors and the Paradigm of Trans‐Scale Autonomous Bio‐Integrated Diagnostics for Addressing Health Complexities

open access: yesElectron, EarlyView.
Physics‐driven advances in optical nanobiosensors for rapid, miniaturized, and point‐of‐care diagnostics for next‐generation decentralized and personalized healthcare based on sensor intelligence. ABSTRACT Public health emergencies and the escalating burden of chronic diseases necessitate a paradigm shift from centralized laboratory testing to rapid ...
Vishal Chaudhary   +5 more
wiley   +1 more source

Propofol-related infusion syndrome happened in a non-critically ill perioperative young patient: A case report

open access: yesSAGE Open Medical Case Reports
Propofol is a commonly used sedative for the induction of clinical anesthesia and sedation maintenance in intensive care unit patients. However, in a minority of patients, prolonged infusion of propofol may cause metabolic acidosis, electrocardiographic ...
Haibo Zhang   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy