Results 61 to 70 of about 135,582 (205)

Offset of pharmacodynamic effects and safety of remifentanil in intensive care unit patients with various degrees of renal impairment [PDF]

, 2003
Introduction: This open label, multicentre study was conducted to assess the times to offset of the pharmacodynamic effects and the safety of remifentanil in patients with varying degrees of renal impairment requiring intensive care. Methods: A total of
Breen, Des, Wilmer, Alexander, Bodenham, Andrew, Bach, Vagn, Bonde, Jan, Kessler, Paul, Albrecht, Sven, Shaikh, Soraya   +7 more
core   +1 more source

Descriptive Analysis of the Relationship Between Continuous Intravenous Insulin Infusion and Triglyceride Levels in Critically Ill Patients Receiving Propofol Infusion

Anesthesia Research
Background/Objectives: Propofol is a preferred agent for ICU sedation. Hypertriglyceridemia occurs in up to 45% of patients on propofol and has been linked with adverse effects.
Sarah R. Peppard, Jayshil J. Patel
doaj   +1 more source

The Effect of Sevoflurane Plus Propofol on Pain and Complications after Laminectomy: A Randomized Double Blind Clinical Trial [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Pain is one of the most important reasons for the patients concern after surgery. The perfect sedative should have properties like rapid onset, least pain and adverse effects.
Aminolah Vasigh, Fatemeh Najafi, Molouk Jaafarpour, Javaher Khajavikhan, Ali Khani   +4 more
doaj   +1 more source

The Impact of Age on Propofol Requirement for Inducing Loss of Consciousness in Elderly Surgical Patients

Frontiers in Pharmacology, 2022
It is generally accepted that geriatric patients are more sensitive to propofol than adults; thus, a dose-adjusted propofol is recommended for these patients during the induction of anesthesia.
Hua Yang, Hui-Min Deng, Hai-Yan Chen, Shu-Heng Tang, Fang Deng, Yu-Gang Lu, Jin-Chao Song   +6 more
doaj   +1 more source

The Growth of Microorganisms in Propofol and Mixtures of Propofol and Lidocaine

Survey of Anesthesiology, 1999
Propofol emulsion supports bacterial growth. Extrinsic contamination of propofol has been implicated as an etiological event in postsurgical infections. When added to propofol, local anesthetics (e.g., lidocaine) alleviate the pain associated with injecting it. Because local anesthetics have antimicrobial activity, we determined whether lidocaine would
I, Wachowski, D T, Jolly, J, Hrazdil, J C, Galbraith, M, Greacen, A S, Clanachan   +5 more
openaire   +3 more sources

Propofol-related infusion syndrome happened in a non-critically ill perioperative young patient: A case report

SAGE Open Medical Case Reports
Propofol is a commonly used sedative for the induction of clinical anesthesia and sedation maintenance in intensive care unit patients. However, in a minority of patients, prolonged infusion of propofol may cause metabolic acidosis, electrocardiographic ...
Haibo Zhang, Yezu Liu, Minlong Liu, Bing Li, Haima Li   +4 more
doaj   +1 more source

Development of Propofol-Encapsulated Liposomes and the Effect of Intranasal Administration on Bioavailability in Rabbits

Pharmaceutics
Background/Objectives: Propofol is frequently used as an intravenous anesthetic and is rapidly metabolized. Therefore, if it could be administered non-invasively (e.g., orally) as premedication, it might hasten emergence from anesthesia, thereby ...
Hitomi Ujita, Hitoshi Higuchi, Yukiko Nishioka, Saki Miyake, Riko Sato, Takuya Miyawaki   +5 more
doaj   +1 more source

Efeitos do propofol sobre o sistema de condução cardíaca Efectos del propofol sobre el sistema de conducción cardíaco Effects of propofol on the cardiac conduction system

Revista Brasileira de Anestesiologia, 2010
JUSTIFICATIVA E OBJETIVOS: Alguns estudos têm demonstrado que o uso do propofol é, algumas vezes, associado a bradiarritmias ou reversão de arritmias para ritmo sinusal.
Paulo Warpechowski, Ari Tadeu Lírio dos Santos, Paulo José Irigon Pereira, Gustavo Glotz de Lima   +3 more
doaj   +1 more source

Sedation-Analgesia in Elective Colonoscopy: Propofol-Fentanyl Versus Propofol-Alfentanil

Brazilian Journal of Anesthesiology, 2013
Background and objectives: Sedation-analgesia is recommended for comfortable colonoscopy procedures, which are invasive and can be painful. This study aimed to compare the combinations of propofol-alfentanil and propofol-fentanyl for sedation-analgesia ...
Hacer Şebnem Türk, Meltem Aydoğmuş, Oya Ünsal, Hakan Mustafa Köksal, Mehmet Eren Açik, Sibel Oba   +5 more
doaj   +1 more source

The influence of storage time and temperature on propofol concentrations in canine blood and plasma [PDF]

PeerJ, 2017
Propofol is an intravenous anesthetic commonly used due to its favorable pharmacokinetic and pharmacodynamic profile. There are discrepancies in the literature about the most appropriate sample for determining propofol concentrations. Although plasma has
Sherry Cox, Joan Bailey, Chika Okafor, Reza Seddighi, Tom Doherty   +4 more
doaj   +2 more sources