Multiple functional neurosteroid binding sites on GABAA receptors [PDF]
, 2019 Neurosteroids are endogenous modulators of neuronal excitability and nervous system development and are being developed as anesthetic agents and treatments for psychiatric diseases.
Akk, Gustav +12 more
core +3 more sources
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Choriocarcinoma is a rare gestational trophoblastic tumour. Propofol is one of the commonly used intravenous anaesthetic agents and exerts an anti-tumour role in multiple cancers.
Hai Sun, Yingjian Wang, Wenyu Zhang
doaj +1 more source
Hemodynamic Stability during Induction of Anesthesia in Elderly Patients: Propofol + Ketamine versus Propofol + Etomidate [PDF]
Journal of Cardiovascular and Thoracic Research, 2013 Introduction: Various methods have been recommended to prevent hemodynamic instability caused by propofol induction. Current study evaluates hemodynamic effects of ketamine and propofol in comparison to etomidate and propofol during anesthesia induction.
Hamzeh Hosseinzadeh +3 more
doaj +1 more source
Effects of gabergic phenols on the dynamic and structure of lipid bilayers: A molecular dynamic simulation approach [PDF]
, 2019 γ-Aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the vertebrate and invertebrate nervous system. GABAA receptors are activated by GABA and their agonists, and modulated by a wide variety of recognized drugs, including barbiturates ...
Garcia, Daniel Asmed +2 more
core +2 more sources
Preventing pain on injection of propofol: A comparison between lignocaine pre-treatment and lignocaine added to propofol [PDF]
, 2004 Publisher's copy made available with the permission of the publisherA randomized double-blind study compared two methods of preventing the pain from injection of propofol, lignocaine pre-treatment followed by propofol and lignocaine added to propofol ...
Barker P. +9 more
core +2 more sources
Transversus abdominis plane block reduces remifentanil and propofol consumption, evaluated by closed-loop titration guided by bispectral index. [PDF]
, 2018 The present prospective, randomized, double-blind study aimed to determine the impact of transversus abdominis plane (TAP) block on propofol and remifentanil consumption, when administered by closed-loop titration guided by processed ...
Jiang, Mei-Ru +7 more
core
Frequency of Predisposing Factor of Nausea and Vomiting After Chest Surgery Under General Anaesthesia [PDF]
, 2019 Background: Postoperative nausea and vomiting are common and distressing postsurgical symptoms. These symptoms are of particular concern in outpatient surgery because they may require additional direct resources, such as supplies and antiemetic ...
Bhatti, S. U. (Sami) +5 more
core +2 more sources
RESPIRATORY EFFECTS OF PROPOFOL-KETAMINE AND PROPOFL-FENTANYL COMBINATIONS FOR TOTAL INTRAVENOUS ANAESTHESIA [PDF]
Kanem Journal of Medical Sciences, 2018 Background:Propofol combined with other intravenous analgesic agents has been used as the sole anaesthetic agent to provide hypnosis and analgesia for various minor and major surgeries.
Ahmed MN +6 more
doaj
Perbedaan Agregasi Trombosit pada Penderita yang Mendapat Propofol dan Penthotal
JAI (Jurnal Anestesiologi Indonesia), 2010 Latar belakang: Perdarahan perioperatif merupakan masalah yang sering dihadapi dalam setiap operasi. Penggunaan obat anestesi induksi mempunyai pengaruh menghambat agregasi trombosit. Propofol dan Penthotal mempengaruhi Agregasi Trombosit.
Arliansah Arliansah +2 more
doaj +1 more source
High-throughput screening in larval zebrafish identifies novel potent sedative-hypnotics [PDF]
, 2018 BACKGROUND: Many general anesthetics were discovered empirically, but primary screens to find new sedative-hypnotics in drug libraries have not used animals, limiting the types of drugs discovered.
Brown, Lauren E. +12 more
core +1 more source