Results 91 to 100 of about 23,350,298 (259)

Likelihood-Based Estimation of a Proportional-Hazard, Competing- Risk Model with Grouped Duration Data [PDF]

open access: yes
This short paper demonstrates two important results related to the estimation of competing-risk models under the proportional-hazards assumption with grouped duration data.
Mark Yuying An
core  

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

open access: yesFEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani   +3 more
wiley   +1 more source

A Simple GMM Estimator for the Semi-Parametric Mixed Proportional Hazard Model [PDF]

open access: yes
Ridder and Woutersen (2003) have shown that under a weak condition on the baseline hazard there exist root-N consistent estimators of the parameters in a semiparametric Mixed Proportional Hazard model with a parametric baseline hazard and unspecified ...
Ridder, Geert, Bijwaard, Govert
core  

Investigating transcription factor dynamics in health and disease using FRAP

open access: yesFEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj   +3 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

n-Person Nonconvex Bargaining: Efficient Proportional Solution [PDF]

open access: yes
For n-person bargaining problems the family of proportional solutions (introduced and characterized by Kalai) is generalized to bargaining problems with non-convex payoff sets.
Mich Tvede, Jens Leth Hougaard
core  

Representation Formulas and Stability Analysis for Hilfer–Hadamard Proportional Fractional Differential Equations

open access: yesFractal and Fractional
This paper introduces a novel version of the Gronwall inequality specifically related to the Hilfer–Hadamard proportional fractional derivative. By utilizing Picard’s method of successive approximations along with the definition of Mittag–Leffler ...
Safoura Rezaei Aderyani   +2 more
doaj   +1 more source

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Chaos-based communication scheme using proportional and proportional-integral observers [PDF]

open access: yes, 2008
In this paper, we propose a new chaos-based communication scheme using the observers. The novelty lies in the masking procedure that is employed to hide the confidential information using the chaotic oscillator.
Ghassemlooy, Zabih   +5 more
core  

Publication trends on proportional reasoning research: A bibliometric analysis using Scopus database

open access: yesInternational Journal of Didactic Mathematics in Distance Education
Proportional reasoning ability is an important ability for students to understand mathematical concepts. Much research has been conducted on this capability, but it is necessary to map existing research to provide a clearer picture of future research ...
Rani Sugiarni, Khairul Hafezad Abdullah
doaj   +1 more source

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