Results 81 to 90 of about 23,350,298 (259)
BMC Medical Research Methodology, 2016 Background In population-based cancer research, piecewise exponential regression models are used to derive adjusted estimates of excess mortality due to cancer using the Poisson generalized linear modelling framework.
Miguel Angel Luque-Fernandez +5 more
doaj +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
Algorithm for Proportional Matrices in Reals and Integers [PDF]
Let R be the set of nonnegative matrices whose row and column sums fall between specific limits and whose entries sum to some fixed h > 0. Closely related axiomatic approaches have been developed to ascribe meanings to the statements: the real matrix fe ...
Michel Balinski, Gabrielle Demange
core
Survival analysis in clinical trials: Basics and must know areas
Perspectives in Clinical Research, 2011 Many clinical trials involve following patients for a long time. The primary event of interest in those studies is death, relapse, adverse drug reaction or development of a new disease.
Ritesh Singh, Keshab Mukhopadhyay
doaj +1 more source
Design and analysis strategies for robust microbiome ageing research
FEBS Letters, EarlyView.The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik +5 more
wiley +1 more source
Cox Proportional Hazard Model for Analysis of Farmers Insurance Premium Payment Period
Berkala SainstekThe sub-sector of agriculture plays a significant role in the national economic order. The crop failure rate is one of the unexpected risks caused by natural disasters, including drought, pest attacks, and floods.
Ayu Rosida +3 more
doaj +1 more source
FEBS Letters, EarlyView.CT10 regulator of kinase (CRK) and CRK‐Like (CRKL) are signaling adaptors driving cell adhesion, motility, differentiation, and proliferation. SH2‐domain containing (SH) proteins are enriched in YXXP motifs which when phosphorylated create preferred binding sites for CRK family SH2 domains.
Phoebe M. Cousens +8 more
wiley +1 more source
Gradual Negotiations and Proportional Solutions [PDF]
I characterize the proportional N-person bargaining solutions by individual rationality, translation invariance, feasible set continuity, and a new axiom - interim improvement.
Rachmilevitch, Shiran
core
Prognostic Factors in Patients With Colorectal Cancer at Hospital Universiti Sains Malaysia
Asian Journal of Surgery, 2010 To determine the 5-year survival rate and prognostic factors for survival in patients with colorectal cancer treated at the Surgical Unit, Hospital Universiti Sains Malaysia (HUSM), Kelantan, Malaysia.
Anis Kausar Ghazali +3 more
doaj +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source