Results 41 to 50 of about 459,261 (336)

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Time to Default in Credit Scoring Using Survival Analysis [PDF]

open access: yesManagement and Economics Review, 2017
Credit risk assesment has been dominated by logistic and probit regression techniques. As the use of credit scoring has expanded over the past 20 years, concerns have been raised about whether its use may unfairly affect minorities. The aim of this paper
Ana Maria SANDICA, Monica DUDIAN
doaj  

Comparison of regression imputation methods of baseline covariates that predict survival outcomes

open access: yesJournal of Clinical and Translational Science, 2021
Introduction: Missing data are inevitable in medical research and appropriate handling of missing data is critical for statistical estimation and making inferences.
Nicole Solomon   +2 more
doaj   +1 more source

joineR: Joint modelling of repeated measurements and time-to-event data [PDF]

open access: yes, 2012
The joineR package implements methods for analysing data from longitudinal studies in which the response from each subject consists of a time-sequence of repeated measurements and a possibly censored time-toevent outcome.
Diggle, Peter   +5 more
core  

Local partial likelihood estimation in proportional hazards regression

open access: yes, 2007
Fan, Gijbels and King [Ann. Statist. 25 (1997) 1661--1690] considered the estimation of the risk function $\psi (x)$ in the proportional hazards model. Their proposed estimator is based on integrating the estimated derivative function obtained through a ...
Chen, Songnian, Zhou, Lingzhi
core   +3 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor   +12 more
wiley   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd   +3 more
wiley   +1 more source

Comparison of methods for estimating the attributable risk in the context of survival analysis

open access: yesBMC Medical Research Methodology, 2017
Background The attributable risk (AR) measures the proportion of disease cases that can be attributed to an exposure in the population. Several definitions and estimation methods have been proposed for survival data.
Malamine Gassama   +3 more
doaj   +1 more source

A mixed model approach for structured hazard regression [PDF]

open access: yes, 2004
The classical Cox proportional hazards model is a benchmark approach to analyze continuous survival times in the presence of covariate information. In a number of applications, there is a need to relax one or more of its inherent assumptions, such as ...
Fahrmeir, Ludwig, Kneib, Thomas
core   +2 more sources

Pathogenic Germline PALB2 and RAD50 Variants in Patients With Relapsed Ewing Sarcoma

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Approximately 10% of patients with Ewing sarcoma (EwS) have pathogenic germline variants. Here, we report two cases: first, a novel germline pathogenic variant in partner and localizer of BRCA2 (PALB2) in a patient with a late EwS relapse. Its impact on homologous recombination is demonstrated, and breast cancer risk is discussed.
Molly Mack   +12 more
wiley   +1 more source

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