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Testing and confidence intervals for high dimensional proportional hazards models [PDF]

open access: yesJournal of The Royal Statistical Society Series B-statistical Methodology, 2014
The paper considers the problem of hypothesis testing and confidence intervals in high dimensional proportional hazards models. Motivated by a geometric projection principle, we propose a unified likelihood ratio inferential framework, including score ...
Ethan X. Fang, Y. Ning, Han Liu
semanticscholar   +1 more source

DeepSurv: personalized treatment recommender system using a Cox proportional hazards deep neural network [PDF]

open access: yesBMC Medical Research Methodology, 2016
BackgroundMedical practitioners use survival models to explore and understand the relationships between patients’ covariates (e.g. clinical and genetic features) and the effectiveness of various treatment options. Standard survival models like the linear
Jared Katzman   +5 more
semanticscholar   +1 more source

The Southern European Atlantic Diet and all-cause mortality in older adults

open access: yesBMC Medicine, 2021
Background The Southern European Atlantic Diet (SEAD) is the traditional diet of Northern Portugal and North-Western Spain. Higher adherence to the SEAD has been associated with lower levels of some cardiovascular risk factors and reduced risk for ...
Adrián Carballo-Casla   +7 more
doaj   +1 more source

Generating Survival Times to Simulate Cox Proportional Hazards Models [PDF]

open access: yes, 2003
This paper discusses techniques to generate survival times for simulation studies regarding Cox proportional hazards models. In linear regression models, the response variable is directly connected with the considered covariates, the regression ...
Augustin, Thomas   +2 more
core   +2 more sources

Violations of proportional hazard assumption in Cox regression model of transcriptomic data in TCGA pan-cancer cohorts

open access: yesComputational and Structural Biotechnology Journal, 2022
Background: Cox proportional hazard regression (CPH) model relies on the proportional hazard (PH) assumption: the hazard of variables is independent of time. CPH has been widely used to identify prognostic markers of the transcriptome.
Zihang Zeng   +7 more
doaj   +1 more source

Survival analysis of irish amyotrophic lateral sclerosis patients diagnosed from 1995-2010. [PDF]

open access: yesPLoS ONE, 2013
IntroductionThe Irish ALS register is a valuable resource for examining survival factors in Irish ALS patients. Cox regression has become the default tool for survival analysis, but recently new classes of flexible parametric survival analysis tools ...
James Rooney   +7 more
doaj   +1 more source

Three-year Survival of Women with Breast Cancer in Basrah, Iraq

open access: yesOman Medical Journal, 2020
Objectives: We sought to determine the overall observed three-year survival rate of women with breast cancer in Basrah, Iraq, and investigate the associated factors. Methods: Data was collected retrospectively from the Oncology Center registry in Basrah,
Jasim N. Al-Asadi, Sundus M. Al-Mayah
doaj   +1 more source

Moving beyond the Cox proportional hazards model in survival data analysis: a cervical cancer study

open access: yesBMJ Open, 2020
Objectives This study explored the prognostic factors and developed a prediction model for Chinese-American (CA) cervical cancer (CC) patients. We compared two alternative models (the restricted mean survival time (RMST) model and the proportional ...
Lixian Li   +3 more
doaj   +1 more source

Survival analysis of postoperative recurrence of meningioma: 176 cases report

open access: yesChinese Journal of Contemporary Neurology and Neurosurgery, 2022
Objective To investigate the influencing factors of postoperative meningioma recurrence. Methods A total of 176 patients with meningioma treated in Beijing Tiantan Hospital, Capital Medical University from May 2010 to January 2011 were included.
HUANG Guan⁃you   +5 more
doaj   +1 more source

Impact of delayed treatment in women diagnosed with breast cancer: A population‐based study

open access: yesCancer Medicine, 2020
The impact of timely treatment on breast cancer‐specific survival may differ by tumor stage. We aim to study the impact of delayed first treatment on overall survival across different tumor stages.
Peh Joo Ho   +5 more
doaj   +1 more source

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