Propranolol in hypertension. [PDF]
Summary Twenty-four hypertensive patients, eleven of whom had angina pectoris as well, have been treated with propranolol in doses up to 400 mg daily. The thirteen patients without angina received methyldopa 2 g daily in addition to propranolol. A significant reduction of systolic and diastolic blood pressure was found in both groups.
Shakul Tewari
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Effect of propranolol on regional myocardial function in anesthetized open-chest dogs with myocardial ischemia [PDF]
Effects of propranolol on ischemic segmental function were studied in anesthetized open-chest dogs. Two segment-length gauges were used for measuring the regional myocardial function: one was sutured on to the left ventricular surface perfused by the ...
Haraoka, Shoichi+7 more
core +1 more source
Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis [PDF]
Background The objective of this systematic review was to determine the effectiveness and safety of propranolol compared to placebo or usual care for improving clinical relevant outcomes in severely burned patients (TBSA \u3e20%).
Ferrada, Paula+5 more
core +3 more sources
Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength [PDF]
Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against bone
Apel+39 more
core +2 more sources
Involvement of Noradrenergic Neurotransmission in the Stress- but not Cocaine-Induced Reinstatement of Extinguished Cocaine-Induced Conditioned Place Preference in Mice: Role for β-2 Adrenergic Receptors [PDF]
The responsiveness of central noradrenergic systems to stressors and cocaine poses norepinephrine as a potential common mechanism through which drug re-exposure and stressful stimuli promote relapse.
A Dzung Lê+86 more
core +3 more sources
Development and optimization of a novel sustained-release dextran tablet formulation for propranolol hydrochloride [PDF]
A novel oral controlled delivery system for propranolol hydrochloride (PPL) was developed and optimized. The in vitro dissolution profiles of sustained-release matrix tablets of racemic PPL were determined and compared with the United States Pharmacopeia
Bataille, Bernard+5 more
core +1 more source
Propranolol as first-line treatment for life-threatening diffuse infantile hepatic hemangioma: a case report [PDF]
[No abstract ...
Clerico, Anna+6 more
core +1 more source
The differentiation of cholesterol and pigment gallstones [PDF]
Gallbladder biles and stones were obtained at 116 cholecystectomies for symptomatic gallstone disease. All 33 patients younger than 50 years had cholesterol stones, whereas 40% of the older patients had pigment stones.
Carey+5 more
core +1 more source
Using a new high-throughput video-tracking platform to assess behavioural changes in Daphnia magna exposed to neuro-active drugs [PDF]
© 2019. ElsevierOne of the major challenges that faces today regulatory risk assessment is to speed up the way of assessing threshold sublethal detrimental effects of existing and new chemical products.
Barata Martí, Carlos+8 more
core +1 more source