Results 1 to 10 of about 99,981 (303)

Design and Evaluation of Dissolving Microneedles for Enhanced Dermal Delivery of Propranolol Hydrochloride

Pharmaceutics, 2021
Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions.
Jingjing He, Zichen Zhang, Xianzi Zheng, Lu Li, Jianping Qi, Wei Wu, Yi Lu   +6 more
doaj   +2 more sources

Propranolol in hypertension. [PDF]

Postgraduate Medical Journal, 1968
Summary Twenty-four hypertensive patients, eleven of whom had angina pectoris as well, have been treated with propranolol in doses up to 400 mg daily. The thirteen patients without angina received methyldopa 2 g daily in addition to propranolol. A significant reduction of systolic and diastolic blood pressure was found in both groups.
S N Tewari
  +11 more sources

Propranolol: A 50-year historical perspective

Annals of Indian Academy of Neurology, 2019
Propranolol is a beta-adrenergic receptor antagonist that was developed by the British scientist Sir James Black primarily for the treatment of angina pectoris, more than 50 years ago.
A V Srinivasan
doaj   +2 more sources

Propranolol 0.2% Eye Micro-Drops for Retinopathy of Prematurity: A Prospective Phase IIB Study

Frontiers in Pediatrics, 2019
Background: Oral propranolol reduces retinopathy of prematurity (ROP) progression, although not safely. Propranolol 0.1% eye micro-drops administered to newborns with stage 2 ROP are well-tolerated, but not sufficiently effective.Methods: A multi-center ...
Luca Filippi, Giacomo Cavallaro, Giacomo Cavallaro, Elettra Berti, Letizia Padrini, Gabriella Araimo, Giulia Regiroli, Giulia Regiroli, Genny Raffaeli, Genny Raffaeli, Valentina Bozzetti, Paolo Tagliabue, Barbara Tomasini, Annalisa Mori, Giuseppe Buonocore, Massimo Agosti, Angela Bossi, Gaetano Chirico, Salvatore Aversa, Pina Fortunato, Silvia Osnaghi, Barbara Cavallotti, Martina Suzani, Maurizio Vanni, Giulia Borsari, Simone Donati, Giuseppe Nascimbeni, Daniel Nardo, Stefano Piermarocchi, Giancarlo la Marca, Giulia Forni, Silvano Milani, Ivan Cortinovis, Maura Calvani, Paola Bagnoli, Massimo Dal Monte, Anna Maria Calvani, Alessandra Pugi, Eduardo Villamor, Gianpaolo Donzelli, Fabio Mosca, Fabio Mosca   +41 more
doaj   +2 more sources

Efficacy and safety of oral propranolol and topical timolol in the treatment of infantile hemangioma: a meta-analysis and systematic review [PDF]

Frontiers in Pharmacology
BackgroundPropranolol, a nonselective β-blocker, is the first-line treatment for infantile hemangioma (IH). Topical timolol has recently been proposed as a novel IH treatment with fewer adverse effects.
Xiaoye Huang, Xiaoye Huang, Wenyue Si, Zhili Zou, Binyao Li, Yide Mu, Wei Zhong, Kaiying Yang   +7 more
doaj   +2 more sources

Propranolol sensitizes prostate cancer cells to glucose metabolism inhibition and prevents cancer progression

Scientific Reports, 2018
Propranolol, a widely used non-selective beta-adrenergic receptor blocker, was recently shown to display anticancer properties. Its potential to synergize with certain drugs has been also outlined.
Laura Brohée, Olivier Peulen, Betty Nusgens, Vincent Castronovo, Marc Thiry, Alain C. Colige, Christophe F. Deroanne   +6 more
doaj   +2 more sources

Effects of propranolol, a β-noradrenergic antagonist, on memory consolidation and reconsolidation in mice

Frontiers in Behavioral Neuroscience, 2016
Memory reconsolidation impairment using the β-noradrenergic receptor blocker propranolol is a promising novel treatment avenue for patients suffering from pathogenic memories, such as post-traumatic stress disorder (PTSD).
Hélène eVillain, Aïcha eBenkahoul, Anne eDrougard, Marie eLafragette, Elodie eMuzotte, Stéphane ePech, Eric eBui, Alain eBrunet, Philippe eBirmes, Pascal eRoullet   +9 more
doaj   +2 more sources

PROPRANOLOL [PDF]

The Lancet, 1967

openalex   +4 more sources

Efficacy and Safety of Propranolol vs Atenolol in Infants With Problematic Infantile Hemangiomas: A Randomized Clinical Trial.

JAMA Otolaryngology - Head and Neck Surgery, 2021
Importance Propranolol has become the first-line therapy for problematic infantile hemangiomas (IHs) that require systemic therapy. However, different adverse events have been reported during propranolol treatment.
Yi Ji, Siyuan Chen, Kaiying Yang, Xuepeng Zhang, Jiangyuan Zhou, Lizhi Li, B. Xiang, T. Qiu, S. Dai, Xian Jiang, Guo-yan Lu, Liqin Qiu, Feiteng Kong, Yongbo Zhang   +13 more
semanticscholar   +1 more source

Plasma Drug Concentration of Propranolol and Genetic Study in Chinese Han Patients With Infantile Haemangioma

Frontiers in Pediatrics, 2022
Background and PurposeThis study was conducted to explore the plasma drug concentration of propranolol in Chinese Han patients with infantile haemangioma (IH) and the influencing factors, as well as the relationship among plasma drug concentrations of ...
Li Li, Lu Yu, Huan He, Li Wei, Zigang Xu, Libo Zhao, Yujuan Sun, Bin Zhang, Yuanxiang Liu, Rui He, Xiaoling Wang, Lin Ma   +11 more
doaj   +1 more source