Results 1 to 10 of about 98,956 (285)

Efficacy and safety assessment of propranolol tablets vs. oral solution for infantile hemangioma: a retrospective study in China [PDF]

Frontiers in Pediatrics
BackgroundPropranolol for infantile hemangiomas (IHs) is effective and relatively safe. However, propranolol has different formulations and there is no consensus on the optimal formulation for IHs.
Wenting Chen, Hua Qian, Qi Sun, Shan Zhang, Lei Zhu, Yafen Wu, Yingying Qian, Bingbing Wang, Wei Li   +8 more
doaj   +2 more sources

New onset bronchial asthma following oral propranolol for infantile hemangioma [PDF]

Respiratory Medicine Case Reports
Propranolol, a nonselective adrenergic beta-receptor blocker, is the first-line drug used for the treatment of infantile hemangiomas (IH). However, its use is contraindicated in patients with bronchial asthma.
Yuki Yamaguchi, Satoshi Horino, Hiroki Miyabayashi, Haruka Aki, Katsushi Miura   +4 more
doaj   +2 more sources

Efficacy and safety of oral propranolol and topical timolol in the treatment of infantile hemangioma: a meta-analysis and systematic review [PDF]

Frontiers in Pharmacology
BackgroundPropranolol, a nonselective β-blocker, is the first-line treatment for infantile hemangioma (IH). Topical timolol has recently been proposed as a novel IH treatment with fewer adverse effects.
Xiaoye Huang, Xiaoye Huang, Wenyue Si, Zhili Zou, Binyao Li, Yide Mu, Wei Zhong, Kaiying Yang   +7 more
doaj   +2 more sources

Plasma Drug Concentration of Propranolol and Genetic Study in Chinese Han Patients With Infantile Haemangioma

Frontiers in Pediatrics, 2022
Background and PurposeThis study was conducted to explore the plasma drug concentration of propranolol in Chinese Han patients with infantile haemangioma (IH) and the influencing factors, as well as the relationship among plasma drug concentrations of ...
Li Li, Lu Yu, Huan He, Li Wei, Zigang Xu, Libo Zhao, Yujuan Sun, Bin Zhang, Yuanxiang Liu, Rui He, Xiaoling Wang, Lin Ma   +11 more
doaj   +1 more source

Propranolol Ameliorates the Antifungal Activity of Azoles in Invasive Candidiasis

Pharmaceutics, 2023
The effectiveness of current antifungal therapies is hampered by the emergence of drug resistance strains, highlighting an urgent need for new alternatives such as adjuvant antifungal treatments.
Venkatesh Mayandi, Wen-Tyng Kang, Darren Shu Jeng Ting, Eunice Tze Leng Goh, Myoe Naing Lynn, Thet Tun Aung, Jamuna Vadivelu, Veluchamy Amutha Barathi, Anita Sook Yee Chan, Rajamani Lakshminarayanan   +9 more
doaj   +1 more source

Design and Evaluation of Dissolving Microneedles for Enhanced Dermal Delivery of Propranolol Hydrochloride

Pharmaceutics, 2021
Oral propranolol hydrochloride has been the first-line treatment for infantile hemangioma (IH), whereas systemic exposure to propranolol has the potential of causing serious adverse reactions.
Jingjing He, Zichen Zhang, Xianzi Zheng, Lu Li, Jianping Qi, Wei Wu, Yi Lu   +6 more
doaj   +1 more source

Propranolol Modulates Cerebellar Circuit Activity and Reduces Tremor

Cells, 2022
Tremor is the most common movement disorder. Several drugs reduce tremor severity, but no cures are available. Propranolol, a β-adrenergic receptor blocker, is the leading treatment for tremor. However, the in vivo circuit mechanisms by which propranolol
Joy Zhou, Meike E. Van der Heijden, Luis E. Salazar Leon, Tao Lin, Lauren N. Miterko, Dominic J. Kizek, Ross M. Perez, Matea Pavešković, Amanda M. Brown, Roy V. Sillitoe   +9 more
doaj   +1 more source

Propranolol blocks osteosarcoma cell cycle progression, inhibits angiogenesis and slows xenograft growth in combination with cisplatin-based chemotherapy

Scientific Reports, 2022
Osteosarcoma is still associated with limited response to standard-of-care therapy and alarmingly elevated mortality rates, especially in low- and middle-income countries.
Luisina M. Solernó, Natasha T. Sobol, María F. Gottardo, Carla S. Capobianco, Maximiliano R. Ferrero, Liliana Vásquez, Daniel F. Alonso, Juan Garona   +7 more
doaj   +1 more source

The Anti-Virulence Activities of the Antihypertensive Drug Propranolol in Light of Its Anti-Quorum Sensing Effects against Pseudomonas aeruginosa and Serratia marcescens

Biomedicines, 2023
The development of bacterial resistance is an increasing global concern that requires discovering new antibacterial agents and strategies. Bacterial quorum sensing (QS) systems play important roles in controlling bacterial virulence, and their targeting ...
Hadil Faris Alotaibi, Haifa Alotaibi, Khaled M. Darwish, El-Sayed Khafagy, Amr S. Abu Lila, Mohamed A. M. Ali, Wael A. H. Hegazy, Samar Zuhair Alshawwa   +7 more
doaj   +1 more source

Efficacy of Combined Topical Timolol and Oral Propranolol for Treating Infantile Hemangioma: A Meta-Analysis of Randomized Controlled Trials

Frontiers in Pharmacology, 2020
BackgroundOral propranolol has become the first-line treatment for infantile hemangioma (IH). However, combined therapy with topical timolol and oral propranolol has been proposed as a more effective IH treatment strategy.
Junbo Qiao, Junjie Lin, Dexin Zhang, Junhua Li, Changkuan Chen, Hongye Yu, Xiaodi Li, Bin Fang   +7 more
doaj   +1 more source