Results 121 to 130 of about 148,383 (342)

Electrokinetic Manipulations Combined With Direct and Ambient Ionization Mass Spectrometry

open access: yesMass Spectrometry Reviews, EarlyView.
ABSTRACT Mass spectrometry (MS) is a powerful analytical technique that typically involves sample preparation and online analytical separation before MS detection. Traditional methods often face bottlenecks in sample preparation and analytical separation, despite the rapid detection capabilities of MS.
Nicholas E. Manicke   +2 more
wiley   +1 more source

Efficacy and safety of oral propranolol and topical timolol in the treatment of infantile hemangioma: a meta-analysis and systematic review

open access: yesFrontiers in Pharmacology
BackgroundPropranolol, a nonselective β-blocker, is the first-line treatment for infantile hemangioma (IH). Topical timolol has recently been proposed as a novel IH treatment with fewer adverse effects.
Xiaoye Huang   +7 more
doaj   +1 more source

Enhanced Retention In The Passive-Avoidance Task By 5-HT1A Receptor Blockade Is Not Associated With Increased Activity Of The Central Nucleus Of The Amygdala [PDF]

open access: yes, 2003
The effect of blockade of S-HT1A receptors was investigated on (1) retention in a mildly aversive passive-avoidance task, and (2) spontaneous single-unit activity of central nucleus of the amygdala (CeA) neurons, a brain site implicated in modulation of ...
Everbach, E. Carr   +5 more
core   +1 more source

Headaches [PDF]

open access: yes, 2006
A 30 year old lady was seen by her family doctor during a busy clinic complaining of three episodes of left-sided headache over the previous four months.
Camilleri, Myriam
core   +1 more source

Propranolol Reduces Cancer Risk

open access: yesMedicine, 2015
&bgr;-Blockers have been reported to exhibit potential anticancer effects in cancer cell lines and animal models. However, clinical studies have yielded inconsistent results regarding cancer outcomes and cancer risk when &bgr;-blockers were used.
P. Chang   +6 more
semanticscholar   +1 more source

Orthostatic Tremor Is Evoked by Muscle Load Without the Need for Orthostatic Position

open access: yesMovement Disorders Clinical Practice, EarlyView.
Abstract Background Primary orthostatic tremor (POT) is a rare movement disorder characterized by a high‐frequency tremor and a considerable feeling of unsteadiness. People with POT are significantly affected in their daily activities and have reduced quality of life.
Karolina af Edholm   +4 more
wiley   +1 more source

Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation

open access: yesStem Cells Translational Medicine, 2015
Infantile hemangiomas (IHs) are the most common vascular tumor and arise from a hemangioma stem cell (HemSC). Propranolol has proved efficacious for problematic IHs. Propranolol is a nonselective β‐adrenergic receptor (βAR) antagonist that can lower cAMP
N. Munabi   +10 more
semanticscholar   +1 more source

The Evolving Landscape of Immunotoxicity: Charting Mechanisms and Future Strategies for Immune Checkpoint Inhibitor Adverse Events

open access: yesMed Research, EarlyView.
ABSTRACT The use of immune checkpoint inhibitors (ICIs) has significantly improved the efficacy of cancer therapy, but their associated immune‐related adverse events (irAEs) can severely compromise treatment safety. This review systematically summarizes the core mechanisms underlying irAEs, which include multi‐organ damage resulting from T‐cell ...
Anqi Lin   +8 more
wiley   +1 more source

Retrospective Evaluation of an Oral Propranolol Delivery Strategy in 25 Cases of Infantile Hemangioma

open access: yesJournal of Plastic and Reconstructive Surgery
Objectives: The majority of infantile hemangiomas shrink on their own, but when there is a chance of functional impairment, ulceration, or aesthetic issues, an active therapeutic intervention is needed.
Shinichi Ashizawa   +8 more
doaj  

Propranolol reduces viability and induces apoptosis in hemangioblastoma cells from von Hippel-Lindau patients

open access: yesOrphanet Journal of Rare Diseases, 2015
BackgroundVon Hippel-Lindau (VHL) disease is a rare oncological disease with an incidence of 1:36,000, and is characterized by the growth of different types of tumors: hemangioblastomas in the central nervous system (CNS) and retina, renal carcinoma ...
Virginia Albiñana   +7 more
semanticscholar   +1 more source

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