Results 131 to 140 of about 152,571 (346)

Ethnic differences in human lymphocytic cyclic AMP production after isoprenaline stimulation and propranolol blockade. [PDF]

, 1985
C. P. Venter, S. Daya, P. H. Joubert, W. J. Strydom   +3 more
openalex   +1 more source

Perspective on This Article from Effect of Long-term Propranolol Treatment on Hepatocellular Carcinoma Incidence in Patients with HCV-Associated Cirrhosis

, 2023
G. Nkontchou, Mounir Aout, Amel Mahmoudi, Dominique Roulot, Valérie Bourcier, Véronique Grando–Lemaire, Nathalie Ganne‐Carrié, Jean–Claude Trinchet, Éric Vicaut, Michel Beaugrand   +9 more
openalex   +1 more source

Propranolol Reduces Cancer Risk

Medicine, 2015
&bgr;-Blockers have been reported to exhibit potential anticancer effects in cancer cell lines and animal models. However, clinical studies have yielded inconsistent results regarding cancer outcomes and cancer risk when &bgr;-blockers were used.
P. Chang, Wen-Yen Huang, Cheng-Li Lin, Tzu-Chuan Huang, Yi-Ying Wu, Jia-Hong Chen, C. Kao   +6 more
semanticscholar   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

The role of propranolol in the treatment of infantile hemangioma

Revista Portuguesa de Cardiologia, 2014
Introduction: Infantile hemangioma (IH) is one of the most common childhood tumors. There are various medical or surgical therapeutic options, all with suboptimal results. Recently, the successful use of propranolol for involution of IH was described. We
Sérgio Laranjo, Glória Costa, Filipa Paramés, Isabel Freitas, José Diogo Martins, Conceição Trigo, Fátima F. Pinto   +6 more
doaj   +1 more source

Propranolol Targets Hemangioma Stem Cells via cAMP and Mitogen-Activated Protein Kinase Regulation

Stem Cells Translational Medicine, 2015
Infantile hemangiomas (IHs) are the most common vascular tumor and arise from a hemangioma stem cell (HemSC). Propranolol has proved efficacious for problematic IHs. Propranolol is a nonselective β‐adrenergic receptor (βAR) antagonist that can lower cAMP
N. Munabi, R. England, A. Edwards, Alison A. Kitajewski, Q. Tan, Andrew Weinstein, Justin E. Kung, Maya Wilcox, J. Kitajewski, C. Shawber, June K Wu   +10 more
semanticscholar   +1 more source

Beyond the Michaelis–Menten: Evaluation of a tQSSA‐Based IVIVE Approach for Predicting In Vivo Intrinsic Clearance From Hepatocyte Assays

CPT: Pharmacometrics &Systems Pharmacology, EarlyView.
ABSTRACT The classical Michaelis–Menten model, under the standard quasi‐steady‐state approximation (sQSSA), is widely used in in vitro‐in vivo extrapolation (IVIVE) studies using hepatocyte or human liver microsomal (HLM) assays to predict intrinsic hepatic clearance (Clint,vitro$$ {\mathrm{Cl}}_{\operatorname{int},\mathrm{vitro}} $$).
Ngoc‐Anh Thi Vu, Yun Min Song, Sang Kyum Kim, Hwi‐yeol Yun, Soyoung Lee, Jae Kyoung Kim, Jung‐woo Chae   +6 more
wiley   +1 more source

Extrasystoles on 24‐h Holter Monitoring During the First Year of Life

Acta Paediatrica, EarlyView.
ABSTRACT Aim To assess the natural course of extrasystoles and their association with tachyarrhythmias on 24‐h Holter monitoring during the first year of life. Methods A retrospective chart review was performed among newborns referred for 24‐h Holter monitoring at Tampere University Hospital from 2011 to 2017.
Asta Uusitalo, Päivi H. Korhonen, Antti Tikkakoski, Pieta Lehtinen, Kaisa Ylänen, Tuija Poutanen   +5 more
wiley   +1 more source

Spontaneous Bacterial Peritonitis Is Associated With High Mortality, Which Interacts With Antibiotic Prophylaxis in a National Cirrhosis Cohort

Alimentary Pharmacology &Therapeutics, EarlyView.
In a national cohort of newly decompensated Veterans with cirrhosis, SBP and recurrences are linked with higher death and need for liver transplant. SBP prophylaxis, whether primary or secondary, worsens resistance and interacts with mortality but not liver transplant.
Scott Silvey, Nilang Patel, Jacqueline G. O'Leary, Timothy Morgan, John D. Markley, Sofia S. Jakab, Heather Patton, Shari Rogal, Jasmohan S. Bajaj   +8 more
wiley   +1 more source

In vitro functional properties of the rat bladder regenerated by the bladder acellular matrix graft. [PDF]

, 1998
PurposeTo assess the response of rat urinary bladder regenerated by the homologous bladder acellular matrix graft (BAMG) to in vitro electrical and pharmacologic stimuli.Materials and methodsIn Sprague-Dawley rats, partial cystectomy (>50%) was ...
Dahiya, R, Dahms, SE, Lue, TF, Nunes, LS, Piechota, HJ, Tanagho, EA   +5 more
core   +1 more source