Results 21 to 30 of about 146,465 (290)

Effect of propranolol on regional myocardial function in anesthetized open-chest dogs with myocardial ischemia [PDF]

, 1978
Effects of propranolol on ischemic segmental function were studied in anesthetized open-chest dogs. Two segment-length gauges were used for measuring the regional myocardial function: one was sutured on to the left ventricular surface perfused by the ...
Haraoka, Shoichi, Ikenaga, Toyotake, Ogino, Yasuhiro, Saito, Daiji, Tawara, Ritsuya, Ueda, Minoru, Yoshida, Hidenori, Yoshioka, Nobuhiko   +7 more
core   +1 more source

Propranolol for severe hemangiomas of infancy.

New England Journal of Medicine, 2008
Despite their self-limited course, infantile capillary hemangiomas can impair vital or sensory functions or cause disfigurement. These authors have observed in 11 children that propranolol can inhibit the growth of these hemangiomas.
C. Léauté-Labrèze, E. Dumas de la Roque, T. Hubiche, F. Boralevi, J. Thambo, A. Taïeb   +5 more
semanticscholar   +1 more source

Safety and effectiveness of propranolol in severely burned patients: systematic review and meta-analysis [PDF]

, 2017
Background The objective of this systematic review was to determine the effectiveness and safety of propranolol compared to placebo or usual care for improving clinical relevant outcomes in severely burned patients (TBSA \u3e20%).
Ferrada, Paula, Foianini, Jorge Esteban, García-Perdomo, Herney Andrés, Gomez, Diego Andrés, Manzano-Nunez, Ramiro, Ordoñez Delgado, Carlos Alberto   +5 more
core   +3 more sources

Splanchnic Venous Compression Enhances the Effects of ß‐Blockade in the Treatment of Postural Tachycardia Syndrome

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Splanchnic venous pooling induced by upright posture triggers a compensatory increase in heart rate (HR), a response that is exaggerated in patients with postural tachycardia syndrome.
Emily C. Smith, André Diedrich, Satish R. Raj, Alfredo Gamboa, Cyndya A. Shibao, Bonnie K. Black, Amanda Peltier, Sachin Y. Paranjape, Italo Biaggioni, Luis E. Okamoto   +9 more
doaj   +1 more source

Low Dose of Propranolol Does Not Affect Rat Osteotomy Healing and Callus Strength [PDF]

, 2014
Experimental studies suggest that the β‐blocker propranolol stimulates bone formation but little work has investigated its effect on fracture healing. In this study, we examined if a low dose of propranolol, previously shown to be preventive against bone
Apel, Arai, Aro, Aspenberg, Baek, Bliziotes, Bonnet, Bonnet, Bostrom, Chenu, Cherruau, Chhabra, Ding, Elefteriou, Elefteriou, Graham, Hara-Irie, Harrison, He, Hohmann, Jeyabalan, Kajimura, Kondo, Long, Mach, Madsen, Marenzana, Marsell, Minkowitz, Moran, Morgan, Pierroz, Pullar, Reid, Rodrigues, Serre, Strömberg, Takeda, Takeda, Togari   +39 more
core   +2 more sources

Facile Synthesis of Propranolol and Novel Derivatives

Journal of Chemistry, 2020
Propranolol is one of the first medications of the beta-blocker used for antihypertensive drugs. This study reports the facile route for the synthesis of propranolol and its novel derivatives.
Vy Anh Tran, Nguyen Hai Tai Tran, Long Giang Bach, Trinh Duy Nguyen, Thi Thuong Nguyen, Tan Tai Nguyen, Thi Anh Nga Nguyen, The Ky Vo, Thu-Thao Thi Vo, Van Thuan Le   +9 more
doaj   +1 more source

Propranolol Sensitizes Vascular Sarcoma Cells to Doxorubicin by Altering Lysosomal Drug Sequestration and Drug Efflux

Frontiers in Oncology, 2021
Angiosarcoma is a rare cancer of blood vessel–forming cells with a high patient mortality and few treatment options. Although chemotherapy often produces initial clinical responses, outcomes remain poor, largely due to the development of drug resistance.
Jhuma Saha, Jong Hyuk Kim, Jong Hyuk Kim, Jong Hyuk Kim, Clarissa N. Amaya, Clarissa N. Amaya, Caleb Witcher, Ali Khammanivong, Derek M. Korpela, David R. Brown, Josephine Taylor, Brad A. Bryan, Brad A. Bryan, Erin B. Dickerson, Erin B. Dickerson, Erin B. Dickerson   +15 more
doaj   +1 more source

Mass spectrometry in ocular drug research

Mass Spectrometry Reviews, EarlyView., 2023
Abstract Mass spectrometry (MS) has been proven as an excellent tool in ocular drug research allowing analyzes from small samples and low concentrations. This review begins with a short introduction to eye physiology and ocular pharmacokinetics and the relevance of advancing ophthalmic treatments.
Eva M. del Amo, Kati‐Sisko Vellonen, Arto Urtti, Tetsuya Terasaki, Anam Hammid, Paavo Honkakoski, Seppo Auriola   +6 more
wiley   +1 more source

Combinative effects of β-elemene and propranolol on the proliferation, migration, and angiogenesis of hemangioma [PDF]

PeerJ, 2023
Hemangioma (HA) is one of the most common benign vascular tumors among children. Propranolol is used as the first-line treatment for hemangioma and is a non-selective blocker of the β-adrenergic receptor.
Zhenyu Wang, Yinxian Chen, Lin Yang, Dunbiao Yao, Yang Shen   +4 more
doaj   +2 more sources

Electrospun nanofibers of polyCD/PMAA polymers and their potential application as drug delivery system [PDF]

Materials Science & Engineering C, v. 54, p. 252-261, 2015, 2015
Herein, we used an electrospinning process to develop highly efficacious and hydrophobic coaxial nanofibers based on poly-cyclodextrin (polyCD) associated with poly(methacrylic acid) (PMAA) that combines polymeric and supramolecular features for modulating the release of the hydrophilic drug, propranolol hydrochloride (PROP).
arxiv   +1 more source