Results 51 to 60 of about 104,112 (336)
The β-blocker Nebivolol Is a GRK/β-arrestin Biased Agonist [PDF]
, 2013 Nebivolol, a third generation β-adrenoceptor (β-AR) antagonist (β-blocker), causes vasodilation by inducing nitric oxide (NO) production. The mechanism via which nebivolol induces NO production remains unknown, resulting in the genesis of much of the ...
Andresen, Bradley T. +9 more
core +3 more sources
BMEMat, EarlyView.This paper summarized the application of 3D bioprinting in the regeneration of various tissues in the oral and craniomaxillofacial fields, including the required biomaterials and printing techniques. Abstract Oral and craniomaxillofacial tissues are essential for maintaining oral functions, including respiration, mastication, swallowing, and speech ...
Huilu Zhan +7 more
wiley +1 more source
Propranolol 0.2% Eye Micro-Drops for Retinopathy of Prematurity: A Prospective Phase IIB Study
Frontiers in Pediatrics, 2019 Background: Oral propranolol reduces retinopathy of prematurity (ROP) progression, although not safely. Propranolol 0.1% eye micro-drops administered to newborns with stage 2 ROP are well-tolerated, but not sufficiently effective.Methods: A multi-center ...
Luca Filippi +41 more
doaj +1 more source
On the Blameworthiness of Forgetting [PDF]
, 2018 It is a mistake to think that we cannot be morally responsible for forgetting because, as a matter of principle, forgetting is outside of our control. Sometimes we do have control over our forgetting.
Bernecker, Sven
core +1 more source
Chemistry &Biodiversity, EarlyView.Involvement of Ca2+ channels in boldine‐induced vascular relaxation. ABSTRACT The regulation of vascular tone plays a fundamental role in blood pressure homeostasis and still represents a significant challenge in clinical practice. Boldine, a naturally occurring alkaloid from Peumus boldus, has emerged as a compound of interest due to its therapeutic ...
Martina Odebrecht Cavichiolo +3 more
wiley +1 more source
Application of Metal‐Organic Framework Composites
ChemistryEurope, EarlyView.This review summarizes the applications of MOF composites in adsorption, energy storage, catalysis, biomedicine, and sensing. It also discusses the functionality of MOF composites from a dimensional perspective. Environmental issues have intensified, and demand for energy continues to grow, making it challenging for conventional materials to meet the ...
Yihao Chen +5 more
wiley +1 more source
Zolmitriptan: a novel portal hypotensive agent which synergizes with propranolol in lowering portal pressure. [PDF]
PLoS ONE, 2013 OBJECTIVE: Only a limited proportion of patients needing pharmacological control of portal hypertension are hemodynamic responders to propranolol.
Mercedes Reboredo +13 more
doaj +1 more source
Evaluation of person-level heterogeneity of treatment effects in published multiperson N-of-1 studies: systematic review and reanalysis. [PDF]
, 2018 OBJECTIVE:Individual patients with the same condition may respond differently to similar treatments. Our aim is to summarise the reporting of person-level heterogeneity of treatment effects (HTE) in multiperson N-of-1 studies and to examine the evidence ...
Balk, Ethan M +8 more
core +1 more source
Clinical Pharmacology &Therapeutics, EarlyView.Data science approaches have been increasingly implemented in healthcare big data to evaluate the safety and effectiveness of drugs. Association discovery is a data mining approach that finds potentially associated elements in high‐dimensional data. We present a novel implementation of the association discovery approach in longitudinal healthcare data ...
George S. Q. Tan +6 more
wiley +1 more source
International Journal of Pediatrics, 2021 Objective. Low-dose nonselective β blockade is an effective treatment for problematic infantile hemangioma (PIH). Screening electrocardiograms (ECG) are performed prior to the initiation of propranolol to minimize the risk of exacerbating undiagnosed ...
James D. Phillips +9 more
doaj +1 more source