Results 81 to 90 of about 96,658 (272)

Movement Disorders Associated with 22q11.2 Microdeletion: A Scoping Review

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Movement disorders have recently emerged as important neurologic manifestations of the 22q11.2 microdeletion that affects nearly one in every 2000 live births. Objective We aimed to map the existing evidence regarding the spectrum, diagnosis and treatment, and etiopathogenesis of movement disorders associated with 22q11.2 ...
Nikolai Gil D. Reyes, Daniel G. Di Luca, Connie Marras, Erik Boot, Ryan K.C. Yuen, Anthony E. Lang, Anne S. Bassett   +6 more
wiley   +1 more source

The Spectrum of Abnormal Tongue Movements: Review of Phenomenology, Etiology, and Differential Diagnosis

Movement Disorders Clinical Practice, EarlyView.
ABSTRACT Background Classifying abnormal tongue movements is challenging due to their varied presentations and limited visibility compared to other body parts. Accurate identification of the phenomenology guides physical examination and can point to specific diagnoses.
Nathaniel Bendahan, Seyed‐Mohammad Fereshtehnejad, Christos Ganos, Emily Swinkin, Anthony E. Lang   +4 more
wiley   +1 more source

Subthalamic Nucleus Deep Brain Stimulation Improves Kinetic Tremor in Parkinson's Disease

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Although resting tremor is a characteristic feature of Parkinson's disease (PD), many patients also suffer from action tremor. Deep brain stimulation (DBS) of the subthalamic nucleus (STN) is effective in reducing motor symptoms. However, it is unclear to what extent STN‐DBS improves action tremor in PD, particularly kinetic tremor.
Iwan Grooters, Bart E.K.S. Swinnen, Yarit Wiggerts, Maarten Bot, Pepijn van den Munckhof, P. Rick Schuurman, Martijn Beudel, Rob M.A. de Bie, Arthur W.G. Buijink   +8 more
wiley   +1 more source

Efficacy and safety of oral propranolol and topical timolol in the treatment of infantile hemangioma: a meta-analysis and systematic review

Frontiers in Pharmacology
BackgroundPropranolol, a nonselective β-blocker, is the first-line treatment for infantile hemangioma (IH). Topical timolol has recently been proposed as a novel IH treatment with fewer adverse effects.
Xiaoye Huang, Xiaoye Huang, Wenyue Si, Zhili Zou, Binyao Li, Yide Mu, Wei Zhong, Kaiying Yang   +7 more
doaj   +1 more source

R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma

eLife, 2019
Propranolol is an approved non-selective β-adrenergic blocker that is first line therapy for infantile hemangioma. Despite the clinical benefit of propranolol therapy in hemangioma, the mechanistic understanding of what drives this outcome is limited ...
Jeroen Overman, Frank Fontaine, Jill Wylie-Sears, Mehdi Moustaqil, Lan Huang, Marie Meurer, Ivy Kim Chiang, Emmanuelle Lesieur, Jatin Patel, Johannes Zuegg, Eddy Pasquier, Emma Sierecki, Yann Gambin, Mohamed Hamdan, Kiarash Khosrotehrani, Gregor Andelfinger, Joyce Bischoff, Mathias Francois   +17 more
doaj   +1 more source

Treatment Continuation and Long‐Term Outcomes of Perampanel in Primary Orthostatic Tremor; A Cohort Study

Movement Disorders Clinical Practice, EarlyView.
Background Primary orthostatic tremor (POT) is a rare hyperkinetic movement disorder with limited and largely ineffective treatment options. Perampanel has been suggested as a therapy, but has so far only been investigated in small studies with short duration.
Wietske A. Babeliowsky, Bart Swinnen, Jeroen Hoogland, Rob M.A. de Bie, Anne‐Fleur van Rootselaar   +4 more
wiley   +1 more source

LC-MS/MS Estimation of Propranolol level in Exhaled Breath Condensate

Pharmaceutical Sciences, 2017
Background: Exhaled breath condensate (EBC) could be used as a non-invasive and alternative specimen to urine and blood for monitoring propranolol levels.
Samin Hamidi 1, Maryam Amini 2, Maryam Khoubnasabjafari 3, Vahid Jouyban-Gharamaleki 4,5, Hossein Sate 6, Abolghasem Jouyban 5,7 *
doaj   +1 more source

Propranolol attenuates hemorrhage and accelerates wound healing in severely burned adults

Critical Care, 2015
IntroductionPropranolol, a nonselective β-blocker, exerts an indirect effect on the vasculature by leaving α-adrenergic receptors unopposed, resulting in peripheral vasoconstriction.
Arham Ali, D. Herndon, Ashish Mamachen, Samir Hasan, C. Andersen, Ro-Jon Grogans, Jordan L. Brewer, Jong O. Lee, Jamie M. Heffernan, O. Suman, C. Finnerty   +10 more
semanticscholar   +1 more source

Update on Medical Treatments for Essential Tremor: An International Parkinson and Movement Disorder Society Evidence‐Based Medicine Review

Movement Disorders, EarlyView.
Abstract Background The first International Parkinson and Movement Disorder Society Evidence‐Based Medicine (MDS‐EBM) review for essential tremor (ET) was published in 2019; since then, the modified Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) methodology was adopted by MDS, and new evidence exists.
Deepa Dash, Verónica Bruno, Petra Schwingenschuh, Kelly E. Lyons, Eng‐King Tan, Claudia M. Testa, Santiago Perez Lloret, Bettina Balint, João Costa, Rob M.A. de Bie, Monty A. Silverdale, Ai Huey Tan, Tiago A. Mestre   +12 more
wiley   +1 more source

Kaposiform hemangioendothelioma: Diagnosis and treatment

Pediatric Investigation, EarlyView.
Vascular endothelial growth factor‐C (VEGF‐C)/vascular endothelial growth factor receptor‐3 (VEGFR‐3) and angiopoietin‐2 (Ang‐2)/tyrosine kinase with immunoglobulin‐like and EGF‐like domain 2 (TIE2) signaling pathways play an important role in lymphangiogenesis.
Yi Tian, Yuanyuan Tian, Li Wei, Zigang Xu, Li Li, Lin Ma   +5 more
wiley   +1 more source