Results 11 to 20 of about 285,382 (122)

The Role of Spin(9) in Octonionic Geometry [PDF]

Axioms 2018, 7(4), 72, 2018
Starting from the 2001 Thomas Friedrich's work on Spin(9), we review some interactions between Spin(9) and geometries related to octonions. Several topics are discussed in this respect: explicit descriptions of the Spin(9) canonical 8-form and its analogies with quaternionic geometry as well as the role of Spin(9) both in the classical problems of ...
arxiv   +1 more source

P8 PROPROTEIN CONVERTASE SUBTILISIN/KEXIN TYPE 9 LEVELS AND ARTERIAL FUNCTION

Artery Research, 2017
Purpose/Background/Objectives: Proprotein convertase subtilisin/kexin type 9 (PCSK9) levels are modestly but significantly associated with increased risk of total cardiovascular events.
Losif Koutagiar, Charalambos Vlachopoulos, Dimitrios Terentes-Printzios, John Skoumas, Nikitas Skliros, Magkas Nikolaos, Antigoni Miliou, Dimitrios Tousoulis   +7 more
doaj   +1 more source

A molecular modeling approach for structure-based virtual screening and identification of novel anti-hypercholesterolemic agents from Grape

Informatics in Medicine Unlocked, 2022
Hypercholesterolemia is a potential cardiovascular hazard that requires immediate therapeutic intervention. Research has shown that 3-Hydroxy-3-methylglutaryl- CoA reductase (HMG CoA reductase) and Proprotein convertase subtilisin/kexin type 9 (PCSK9 ...
Precious A. Akinnusi, Samuel O. Olubode, Adebowale A. Alade, Samad A. Ahmed, Susan F. Ayekolu, Taiwo M. Ogunlade, Damilola J. Gbore, Olayemi D. Rotimi, Abigail O. Ayodele   +8 more
doaj  

The 9 Aurigae System [PDF]

Mon.Not.Roy.Astron.Soc. 263 (1993) 781, 1993
The F0 V star 9 Aur A exhibits an irregular variability of amplitude $\approx $0.1 magnitude at optical wavelengths. The variations are too slow for it to be a $\delta$ Scuti-type star. There is no evidence for a close, interacting companion or ring of dust, either from infrared, ultraviolet, or speckle data.
arxiv   +1 more source

Plasma Proprotein Convertase Subtilisin/kexin Type 9 (PCSK9) in the Acute Respiratory Distress Syndrome

Frontiers in Medicine, 2022
BackgroundProprotein convertase subtilisin/kexin type 9 (PCSK9) is a serine protease that is a mediator of the immune response to sepsis. PCSK9 is also highly expressed in pneumocytes and pulmonary endothelial cells.
Thomas S. Metkus, Bo Soo Kim, Steven R. Jones, Seth S. Martin, Steven P. Schulman, Thorsten M. Leucker   +5 more
doaj   +1 more source

Perkembangan Implikasi Biologi dan Klinis Proprotein Convertase Subtilisin-Kexin 9

Majalah Kardiologi Indonesia, 2017
Pada tahun 2003 Proprotein Convertase Subtilisin-Kexin 9 (PCSK9) berhasil diidentifikasi.1 PCSK9 berfungsi meningkatkan kadar LDL Cholesterol (LDL-C) melalui degradasi LDL Receptor (LDLR).2 Penemuan PCSK9 telah merevolusi serta merupakan perkembangan ...
doaj   +1 more source

Sex difference in circulating PCSK9 and its clinical implications

Frontiers in Pharmacology, 2022
Proprotein convertase subtilisin kexin type 9 (PCSK9) is a proprotein convertase that increases plasma low-density lipoprotein cholesterol (LDL-C) levels by triggering the degradation of LDL receptors (LDLRs).
Fang Jia, Si-Fan Fei, De-Bing Tong, Cong Xue, Jian-Jun Li   +4 more
doaj   +1 more source

Proprotein Convertase Subtilisin/Kexin Type 9 Deficiency Reduces Melanoma Metastasis in Liver

Neoplasia: An International Journal for Oncology Research, 2012
High circulating cholesterol is associated with hypercholesterolemia, atherosclerosis, and stroke. However, the relation between cholesterol and tumorigenesis/metastasis is controversial.
Xiaowei Sun, Rachid Essalmani, Robert Day, Abdel M. Khatib, Nabil G. Seidah, Annik Prat   +5 more
doaj   +1 more source

Levels of proprotein convertase subtilisin/kexin type 9 in patients with acute myocardial infarction

Российский кардиологический журнал, 2020
Aim. To study the levels of proprotein convertase subtilisin/kexin type 9 (PCSK9) in patients with acute myocardial infarction (MI).Material and methods. The study included 74 patients with acute MI.
A. D. Gimadeeva, A. S. Galyavich, Z. M. Galeeva, L. V. Baleeva   +3 more
doaj   +1 more source

Proprotein convertase subtilisin kexin 9 inhibitors: Current status and future directions

Journal of Clinical and Preventive Cardiology, 2017
The discovery of proprotein convertase subtilisin kexin 9 (PCSK9) has considerably changed the therapeutic options in the field of lipid management. PCSK9 reduces low-density lipoprotein receptor (LDLR) recycling, leading to a decrease of LDL cholesterol
JPS Sawhney, Saurabh Bagga
doaj   +1 more source