Results 31 to 40 of about 20,653 (230)

Congenital Bands with Intestinal Malrotation after Propylthiouracil Exposure in Early Pregnancy

open access: yesCase Reports in Endocrinology, 2015
Exposure to propylthiouracil in early pregnancy may be associated with an increased risk of birth defects. But the spectrum of associated congenital anomalies is not yet well defined.
Alexander A. Leung   +4 more
doaj   +1 more source

Hypothyroidism and Fertility: An Animal Model follows up in The Second-Generation [PDF]

open access: yesCell Journal, 2022
Objective: Hypothyroidism is known as the most common endocrine disorder. The prevalence of hypothyroidism in the female and male population is 2% and 0.2%, respectively.
Faezeh Panahandeh   +6 more
doaj   +1 more source

Propylthiouracil-induced cutaneous vasculitis [PDF]

open access: yes, 2008
The use of propylthiouracil (PTU) is associated with the development of different auto-antibodies, amongst them are antineutrophil cytoplasmic antibodies (ANCA) that are involved in the pathogenesis of ANCA associated systemic vasculitis.
Costa, Leonardo Atem Gonçalves A.   +4 more
core   +2 more sources

Rational Coformer Selection in the Development of 6-Propyl-2-thiouracil Pharmaceutical Cocrystals

open access: yesPharmaceuticals, 2023
Pharmaceutical multicomponent solids have proved to efficiently modulate the physicochemical properties of active pharmaceutical ingredients. In this context, polyphenols are interesting coformers for designing pharmaceutical cocrystals due to their wide
Francisco Javier Acebedo-Martínez   +7 more
doaj   +1 more source

Study the Effects of Ginger (Zingiber officinale) Extract on Serum Lipid in Hypothyroidism Male Rats Induce by Propylthiouracil

open access: yesKufa Journal for Veterinary Medical Sciences, 2014
This study was undertaken to investigate the protective role of Ginger   against the hypothyroidism induce by Propylthiouracil in male rats on serum lipids.
Nabeel M. N. Al-Sharafi   +1 more
doaj   +1 more source

Simultaneous Quantification of Propylthiouracil and Its N-β-d Glucuronide by HPLC-MS/MS: Application to a Metabolic Study

open access: yesPharmaceuticals, 2021
Propylthiouracil (PTU) is commonly prescribed for the management of hyperthyroidism and thyrotoxicosis. Although the exact mechanism of action is not fully understood, PTU is associated with hepatoxicity in pediatric population.
Min Li   +7 more
doaj   +1 more source

Participants with Normal Weight or with Obesity Show Different Relationships of 6-n-Propylthiouracil (PROP) Taster Status with BMI and Plasma Endocannabinoids

open access: yesScientific Reports, 2017
Reduced taste sensitivity to 6-n-propylthiouracil (PROP), a genetic trait regarded as a general index for oral chemosensory perception, has been associated with a calorie-rich food preference and lower circulating endocannabinoid levels in participants ...
G. Carta   +9 more
semanticscholar   +1 more source

Propylthiouracil-induced antineutrophil cytoplasmic antibody-associated vasculitis and agranulocytosis in a patient with Graves’ disease

open access: yesEndocrinology, Diabetes & Metabolism Case Reports, 2019
Summary This case is the first to describe a patient who experienced concomitant agranulocytosis and anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitis as an adverse effect of propylthiouracil treatment for Graves’ disease.
M. Tomkins   +3 more
semanticscholar   +1 more source

A Devastating Storm [PDF]

open access: yes, 2013
Case Report A 26-year-old female with no significant medical history presented with palpitations and shortness of breath. Two weeks prior, she experienced rhinorrhea and congestion.Vital signs on admission were temperature 96.6°F, heart rate 252 beats ...
Merrill, MD, Eve
core   +2 more sources

First objective evaluation of taste sensitivity to 6-n-propylthiouracil (PROP), a paradigm gustatory stimulus in humans

open access: yesScientific Reports, 2017
Practical and reliable methods for the objective measure of taste function are critically important for studying eating behavior and taste function impairment. Here, we present direct measures of human gustatory response to a prototypical bitter compound,
G. Sollai   +7 more
semanticscholar   +1 more source

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