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Renin, Prorenin, and the (Pro)Renin Receptor
2009The discovery of a receptor for renin and for its inactive precursor prorenin, and the introduction of renin inhibitors in therapeutic, has renewed the interest for the physiology of the renin angiotensin system (RAS) and has brought prorenin back in the spotlight.
Genevieve Nguyen, Aurelie Contrepas
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Prorenin in plasma and kidney.
Federation proceedings, 1983Circulating prorenin is an enzymatically inactive form of renin, also present in kidney, which can be activated in vitro. Its biochemical properties and physiological behavior suggest that it may be a biosynthetic precursor of active renin. However, in contrast to typical prohormones, the normal plasma concentrations of prorenin are much higher than ...
J E, Sealey, S A, Atlas, J H, Laragh
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The placental prorenin/prorenin receptor system
Placenta, 2017Samantha Rodrigues +5 more
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Processing and sorting of human prorenin
Cell Biophysics, 1991W A, Hsueh, Y S, Do, P H, Wang
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Chronic Increases in Circulating Prorenin Are not Associated With Renal or Cardiac Pathologies
Hypertension, 2009Timothy L Reudelhuber +1 more
exaly
Prorenin has high affinity multiple binding sites for (pro)renin receptor
Biochimica Et Biophysica Acta - Proteins and Proteomics, 2009Atsuhiro Ichihara +2 more
exaly