Results 101 to 110 of about 425,349 (313)

Cars2‐Mediated Cysteine Catabolism Drives Brown Fat Development and Thermogenesis Through Persulfidating EBF2

open access: yesAdvanced Science, EarlyView.
We demonstrate that Cars2, a cysteine catabolic enzyme in mouse iBAT, is critical for cold tolerance and brown adipocyte differentiation. Through its CPERS activity, Cars2 produces CysSSH/H2S to induce EBF2 persulfidation, promoting its interaction with PPARγ and BRG1 to enhance thermogenic gene expression.
Xin Peng   +8 more
wiley   +1 more source

Impacting prospective teachers’ beliefs about mathematics

open access: yesZDM, 2012
This study investigated: (1) the changes in the beliefs about mathematics held by 25 prospective elementary teachers as they went through a university mathematics course that aimed, among other things, to promote a problem-solving view about mathematics; and (2) the possible factors that accounted for the observed changes.
Shilling-Traina, L, Stylianides, G
openaire   +1 more source

Mass‐Produced and High‐Performance Nanowell Biosensor Fabricated via Semiconductor Manufacturing for Rapid and Accurate COVID‐19 Diagnosis in the Clinical Field

open access: yesAdvanced Science, EarlyView.
A semiconductor‐fabricated nanowell biosensor enables rapid, scalable, and highly reproducible detection of SARS‐CoV‐2 antigens from nasal swabs within ∼10 minutes. Clinical validation in 249 retrospective and 243 prospective patient samples demonstrates high sensitivity and specificity, minimal cross‐reactivity, and robust batch‐to‐batch ...
Yoo Min Park   +11 more
wiley   +1 more source

The Science Studio – A Workshop Approach to Introductory Physical Science [PDF]

open access: yes, 2002
This paper describes the Science Studio, an innovative workshop approach for instruction in a physical science course that combines aspects of traditional lecture and laboratory.
Chaudhury, S. R.
core   +1 more source

NQO1‐Mediated Anoikis Resistance and Immune Evasion Define a High‐Risk Multi‐Omic Subtype for Precision Management of T1 High‐Grade Bladder Cancer

open access: yesAdvanced Science, EarlyView.
Multi‐omic profiling of T1 high‐grade bladder cancer identifies a high‐risk subtype (T1HG1) driven by NQO1, which couples anoikis resistance with immune evasion. NQO1 orchestrates macrophage–T cell crosstalk suppression via CXCL9 modulation. Pharmacological NQO1 inhibition with skullcapflavone II enhances cisplatin efficacy, representing a promising ...
Bin Guo   +20 more
wiley   +1 more source

Transcriptomic and Neuroimaging Decoding of Brain‐Immune Crosstalk in Thyroid Eye Disease

open access: yesAdvanced Science, EarlyView.
This study employed an imaging transcriptomics framework integrating resting‐state fMRI with Allen Human Brain Atlas transcriptomic data, coupled with peripheral blood RNA sequencing, to decode brain‐immune crosstalk in thyroid eye disease. Frontal, parietal, subcortical, and brainstem regions were identified as key neuroimmune‐ vulnerable regions ...
Haiyang Zhang   +15 more
wiley   +1 more source

Educators of Prospective Teachers Hesitate to Embrace Evolution due to Deficient Understanding of Science/Evolution and High Religiosity [PDF]

open access: yes, 2012
Acceptance of evolution by educators of prospective teachers remains superficially studied despite their role in having mentored schoolteachers whose weak support of evolution is known.
Espinosa, Avelina   +1 more
core   +2 more sources

Self‐Heating and Thermal Gradient in Solid‐State Batteries: Friend or Foe?

open access: yesAdvanced Energy Materials, EarlyView.
This work investigates the role of self‐heating and thermal gradients derived from the kinetics/transport interactions within the cathode microstructure, electrode architecture, and operating regimes, thus encouraging a mechanism‐centric design of anode‐free solid‐state batteries for next‐generation high‐power applications.
Abhinand Ayyaswamy   +2 more
wiley   +1 more source

COMPUTER SELF-EFFICACY OF PROSPECTIVE PHYSICAL EDUCATION TEACHERS

open access: yesJournal on Efficiency and Responsibility in Education and Science, 2014
This study investigated the computer self-efficacy of Turkish prospective physical education teachers. The research group consisted of 173 prospective physical education teachers.
ÜNLÜ, Hüseyin, SÜEL, Emin
doaj   +1 more source

EUROPEAN EXPERIENCE IN TRAINING PROSPECTIVE TEACHERS

open access: yesLeader. Elite. Society, 2018
The authors have analysed the experience in training prospective teachers in a number of European countries: the United Kingdom, Germany, France, and Denmark. The standards of training, the requirements to the personality of a modern European teacher, the main principles, methods and forms of training prospective teachers as well as the peculiarities ...
Grineva, Valentina   +2 more
openaire   +3 more sources

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