Results 101 to 110 of about 78,509 (319)

Commonalities of platelet dysfunction in heart failure with preserved ejection fraction and underlying comorbidities

ESC Heart Failure, Volume 12, Issue 2, Page 1013-1028, April 2025.
Abstract Heart failure with preserved ejection fraction (HFpEF) is characterized by a lack of a specific targeted treatment and a complex, partially unexplored pathophysiology. Common comorbidities associated with HFpEF are hypertension, atrial fibrillation, obesity and diabetes.
Giorgia D'Italia, Blanche Schroen, Judith M.E.M. Cosemans   +2 more
wiley   +1 more source

Lipid Mediators in Inflammation [PDF]

, 2016
Lipids are potent signaling molecules that regulate a multitude of cellular responses, including cell growth and death and inflammation/infection, via receptor-mediated pathways. Derived from polyunsaturated fatty acids (PUFAs), such as arachidonic acid (
Bennett, M, Gilroy, DW
core   +1 more source

Mitochondrial targets in ischaemic heart disease and heart failure, and their potential for a more efficient clinical translation. A scientific statement of the ESC Working Group on Cellular Biology of the Heart and the ESC Working Group on Myocardial Function

European Journal of Heart Failure, EarlyView.
Improving clinical translation of mitoprotective therapies. 31P MRI, phosphorus‐31 magnetic resonance imaging; hiPSC‐CM, human‐induced pluripotent stem cell‐derived cardiomyocyte; IHD, ischaemic heart disease. Abstract Acute myocardial infarction (MI) remains a major cause of death and disability worldwide.
Melanie Paillard, Mahmoud Abdellatif, Ioanna Andreadou, Christian Bär, Luc Bertrand, Bianca J.J.M. Brundel, Gemma Chiva‐Blanch, Sean M. Davidson, Dana Dawson, Fabio Di Lisa, Paul Evans, Zoltan Giricz, Derek J. Hausenloy, Petra Kleinbongard, Frank Lezoualc'h, Elisa Liehn, Christoph Maack, Ange Maguy, Elizabeth Murphy, Cinzia Perrino, Maurizio Pesce, Peter P. Rainer, Katrin Streckfuss‐Bömeke, Matthias Thielmann, Rong Tian, Carlo G. Tocchetti, Jolanda Van Der Velden, Sophie Van Linthout, Serena Zacchigna, Thomas Krieg   +29 more
wiley   +1 more source

N-3 fatty acids as resolvents of inflammation in the A549 cells [PDF]

, 2015
Background Fatty acids and their derivatives are one of the most crucial inflammation mediators. The aim of our study was to evaluate the impact of polyunsaturated fatty acids as eicosanoids precursors on the A549 cell line.
Czepiel, Jacek, Gdula-Argasińska, Joanna, Grzywacz, Agata, Jurczyszyn, Artur, Librowski, Tadeusz, Perucki, William, Wojtoń, Katarzyna, Woźniakiewicz, Aneta, Woźniakiewicz, Michał   +8 more
core   +1 more source

Application of Bryophytes to Foods, Food Additives and Phytomedicines

Food Chemistry International, EarlyView.
Little attention has been paid to the bryophytes for use in the human diet, despite the presence of 23,000 species worldwide. (Marchantia polymorpha). ABSTRACT Little attention has been paid to the bryophytes for application on the human diet, despite the presence of 23,000 species worldwide.
Yoshinori Asakawa, Jianbo Xiao
wiley   +1 more source

Differential expression and regulation of microsomal prostaglandin E(2) synthase in human fetal membranes and placenta with infection and in cultured trophoblast cells.

Journal of Clinical Endocrinology and Metabolism, 2003
We have evaluated the effect of chorioamnionitis on the protein expression of microsomal and cytosolic prostaglandin E(2) synthases (mPGES and cPGES) in preterm human placentae (PL) and fetal membranes (FM), by Western blot and immunohistochemistry, as ...
M. Premyslova, Wei Li, N. Alfaidy, A. Bocking, Karen Campbell, W. Gibb, J. Challis   +6 more
semanticscholar   +1 more source

Potential roles of microsomal prostaglandin E synthase-1 in rheumatoid arthritis

Inflammation and Regeneration, 2011
Rheumatoid arthritis (RA) is a chronic autoimmune disease which primarily affects the synovial joints leading to inflammation, pain and joint deformities. Nonsteroidal anti-inflammatory drugs (NSAIDs) and glucocorticoids, both of which inhibit cyclooxygenase (COX), have been extensively used for treating RA patients.
Rahul Matnani, Shinichi Kawai, Fumiaki Kojima, Leslie J. Crofford, Fumitaka Ushikubi   +4 more
openaire   +4 more sources

Curcuma comosa‐Derived Diarylheptanoid Ameliorates Ulcerative Colitis by Inhibiting JNK/NF‐κB and Activating AMPK/Nrf2 Pathways

Food Frontiers, EarlyView.
In this study, we isolated and investigated the protective effect of 1,7‐diphenyl‐(6E)‐6‐hepten‐3‐ol (DPHP) against ulcerative colitis. Our results demonstrate that DPHP administration effectively alleviates colitis symptoms, inhibits inflammation, and strengthens antioxidant defense mechanisms. A combination of network pharmacology analysis, molecular
Van‐Long Truong, Razanamanana H. G. Rarison, Woo‐Sik Jeong   +2 more
wiley   +1 more source

Prostaglandin E2 involvement in the reproduction of small abalone, Haliotis diversicolor

Aquaculture and Fisheries
Prostaglandin E2 (PGE2) has been reported to be involved in reproduction as one of the most abundant and widely distributed prostaglandins in invertebrates.
Yawei Shen, Lingling Li, Xuan Luo, Miaoqin Huang, Caihuan Ke, Weiwei You, Weidong Li   +6 more
doaj  

Prolonged Hypercapnia-Evoked Cerebral Hyperemia via K ⁺ Channel– and Prostaglandin E ₂ –Dependent Endothelial Nitric Oxide Synthase Induction [PDF]

, 2000
Taline Najarian, Anne Marilise Marrache, Isabelle Dumont, Pierre Hardy, Martin Beauchamp, Xin Hou, Krishna G. Peri, Fernand Gobeil, Daya R. Varma, Sylvain Chemtob   +9 more
openalex   +1 more source