Results 231 to 240 of about 78,509 (319)

Deletion of microsomal prostaglandin E synthase-1 augments prostacyclin and retards atherogenesis

Proceedings of the National Academy of Sciences of the United States of America, 2006
Miao Wang, Alicia M. Zukas, Yiqun Hui, E. Ricciotti, E. Puré, G. FitzGerald   +5 more
semanticscholar   +1 more source

Effects of AF3442 [N-(9-ethyl-9H-carbazol-3-yl)-2-(trifluoromethyl)benzamide], a novel inhibitor of human microsomal prostaglandin E synthase-1, on prostanoid biosynthesis in human monocytes in vitro

, 2009
Annalisa Bruno, Luigia Di Francesco, Isabella Coletta, Giorgina Mangano, Maria Alessandra Alisi, Lorenzo Polenzani, Claudio Milanese, Paola Anzellotti, Emanuela Ricciotti, Melania Dovizio, Andrea Di Francesco, Stefania Tacconelli, Marta L. Capone, Paola Patrignani   +13 more
openalex   +2 more sources

Molecular Alterations in Ferroptosis and the Effects of Resveratrol: A Systematic Review

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.
Ferroptosis is a cell death mechanism characterized by iron overload, accumulation of reactive oxygen species, deficits in glutathione metabolism, lipid peroxidation, and mitochondrial impairments. Resveratrol can prevent or reverse these alterations by chelating iron and upregulating antioxidant defenses. ABSTRACT Ferroptosis is an iron‐dependent cell
Ana Beatriz Dos Santos, Júlio Santos‐Terra, Jaqueline Vieira Carletti, Iohanna Deckmann, Carmem Gottfried   +4 more
wiley   +1 more source

Analysis of the Expression and Activity of Cyclooxygenases COX-1 and COX-2 in THP-1 Monocytes and Macrophages Cultured with Xenogenic Collagen Matrices Biofunctionalized with the Injectable Platelet-Rich Fibrin. [PDF]

Int J Mol Sci
Droździk A, Barczak K, Bosiacki M, Kupnicka P, Cenariu D, Uriciuc WA, Chlubek D, Lipski M, Droździk M, Baranowska-Bosiacka I.   +9 more
europepmc   +1 more source

Carvacrol Coadministration Ameliorates Lambda‐Cyhalothrin‐Induced Peripheral Neuropathy in Rats: Behavioral and Molecular Evidence

Journal of Biochemical and Molecular Toxicology, Volume 39, Issue 7, July 2025.
This study investigates the peripheral neuropathy induced by the pesticide Lambda‐cyhalothrin (CYH) and how carvacrol (CRV) treatment reduces these effects. CYH causes neurological disorders, oxidative stress, and inflammation, while CRV reverses these harmful effects with its antioxidant, anti‐inflammatory, and antiapoptotic properties.
Özge Kandemir, Mustafa İleritürk, Cihan Gür, Nurhan Akaras, Hasan Şimşek, Selçuk Yılmaz, Fatih Mehmet Kandemir   +6 more
wiley   +1 more source

Microsomal Prostaglandin E Synthase-1 Controls Colonic Prostaglandin E₂ Production and Exerts a Protective Effect on Colitis Induced by Trinitrobenzene Sulfonic Acid in Mice. [PDF]

Int J Mol Sci
Kojima F, Hioki Y, Sekiya H, Kashiwagi H, Iizuka Y, Eto K, Maehana S, Kawakami F, Kubo M, Ishibashi H, Ichikawa T.   +10 more
europepmc   +1 more source

On the role of the inducible enzymes iNOS and COX-2 in colitis [PDF]

, 2002
Kankuri, Esko
core  

Microsomal prostaglandin E synthase-1 is involved in the brain ischemic injury

, 2010
Yuri Ikeda‐Matsuo
openalex   +2 more sources

Sustainable Microextraction Using Switchable Solubility Solvent for the Liquid Chromatographic Determination of Three Profenoid Drugs in Urine Samples

Journal of Separation Science, Volume 48, Issue 7, July 2025.
ABSTRACT Herein, a switchable solubility solvent (sodium salicylate) was employed for the microextraction of “profenoid” drugs (i.e., ketoprofen, fenoprofen, and flurbiprofen) from human urine samples. This approach utilizes the phase transition of salicylic acid (0.75 mol/L) by altering the sample's pH (addition of 10 µL of H3PO4 10 M), facilitating ...
Christina Patakidou, Marianna Ntorkou, Constantinos K. Zacharis   +2 more
wiley   +1 more source

Reactive oxygen and nitrogen species: multifaceted regulators of ovarian activity†. [PDF]

Biol Reprod
Bezdíček J, Sekaninová J, Janků M, Makarevič A, Luhová L, Dujíčková L, Petřivalský M.   +6 more
europepmc   +1 more source