Results 11 to 20 of about 266,537 (289)

Structures of human prostaglandin F2α receptor reveal the mechanism of ligand and G protein selectivity

Nature Communications, 2023
Prostaglandins and their receptors regulate various physiological processes. Carboprost, an analog of prostaglandin F2α and an agonist for the prostaglandin F2-alpha receptor (FP receptor), is clinically used to treat postpartum hemorrhage (PPH). However,
Xiuqing Lv, Kaixuan Gao, Jia Nie, Xin Zhang, Shuhao Zhang, Yinhang Ren, Xiaoou Sun, Qi Li, Jingrui Huang, Lijuan Liu, Xiaowen Zhang, Weishe Zhang, Xiangyu Liu   +12 more
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Ascorbic acid enhances the inhibitory effect of aspirin on neuronal cyclooxygenase-2-mediated prostaglandin E2 production. [PDF]

, 2006
Inhibition of neuronal cyclooxygenase-2 (COX-2) and hence prostaglandin E2 (PGE2) synthesis by non-steroidal anti-inflammatory drugs has been suggested to protect neuronal cells in a variety of pathophysiological situations including Alzheimer's disease ...
Akundi, Ravi S., Appel, Kurt, Bhatia, Harsharan S., Candelario-Jalil, Eduardo, Fiebich, Bernd L., Hull, Michael, Lieb, Klaus, Munoz, Eduardo   +7 more
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Prostaglandin E Positively Modulates Endothelial Progenitor Cell Homeostasis: An Advanced Treatment Modality for Autologous Cell Therapy [PDF]

, 2009
Aims: The mobilization of endothelial progenitor cells (EPC) and their functioning in postnatal neovascularization are tightly regulated. To identify new modulators of EPC homeostasis, we screened biologically active prostaglandin E compounds for their ...
Heeschen, Christopher, Hermann, Patrick C., Herrler, Tanja, Huber, Stephan, Kopp, Reinhard, Leicht, Simon F., Schwarz, Theresa M.   +6 more
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Up-regulation of cytosolic prostaglandin E synthase in fetal-membrane and amniotic prostaglandin E2 accumulation in labor.

PLoS ONE, 2021
Prostaglandin E2 (PGE2) is known to have important roles in labor, but the detailed mechanism underlying the spontaneous human labor remains unknown.
Nanase Takahashi, Toshiaki Okuno, Hiroki Fujii, Shintaro Makino, Masaya Takahashi, Mai Ohba, Kazuko Saeki, Atsuo Itakura, Satoru Takeda, Takehiko Yokomizo   +9 more
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Polyunsaturated fatty acid-derived lipid mediators and T cell function [PDF]

, 2014
Copyright © 2014 Nicolaou, Mauro, Urquhart and Marelli-Berg . This is an open- access article distributed under the terms of the Creative Commons Attribution License (CC BY) .
Marelli-Berg, F, Mauro, C, Nicolaou, A, Urquhart, P   +3 more
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Prostaglandins and related factors: XIX. Thin-layer chromatography of prostaglandins

Journal of Lipid Research, 1964
Methods are described for separation of all known prostaglandins and some derivatives as free acids and methyl esters by thin-layer chromatography both on analytical and preparative scales. The use of silica gel containing silver nitrate was required for
Krister Gréen, Bengt Samuelsson
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Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain

Journal of Neuroinflammation, 2017
Background Astrocytic aromatization and consequent increases in estradiol are neuroprotective in the injured brain. In zebra finches, cyclooxygenase-activity is necessary for injury-induced aromatase expression, and increased central estradiol lowers ...
Alyssa L. Pedersen, Colin J. Saldanha
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Clinical Significance of Prostaglandins in the Formation of Courses of Bacterial Intestinal Infections in Children

Zdorovʹe Rebenka, 2015
The levels of prostaglandin E and prostaglandin F2α in the blood serum of infants with bacterial intestinal infections have been investigated. The connection between increased indexes during acute phase of the disease and the type of its course has been ...
T.S. Zharkova
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Attenuation of ischemic liver injury by prostaglandin E1 analogue, misoprostol, and prostaglandin I2 analogue, OP-41483 [PDF]

, 1998
Background: Prostaglandin has been reported to have protective effects against liver injury. Use of this agent in clinical settings, however, is limited because of drugrelated side effects.
Ishizaki, N, Jin, MB, Kawashima, Y, Shimamura, T, Starzl, TE, Todo, S, Totsuka, E, Urakami, A, Zhu, Y   +8 more
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Microvascular COX-2/mPGES-1/EP-4 axis in human abdominal aortic aneurysm

Journal of Lipid Research, 2013
We investigated the prostaglandin (PG)E2 pathway in human abdominal aortic aneurysm (AAA) and its relationship with hypervascularization. We analyzed samples from patients undergoing AAA repair in comparison with those from healthy multiorgan donors ...
Mercedes Camacho, Jaume Dilmé, David Solà-Villà, Cristina Rodríguez, Sergi Bellmunt, Laura Siguero, Sonia Alcolea, José-María Romero, José-Román Escudero, José Martínez-González, Luis Vila   +10 more
doaj   +1 more source