Results 211 to 220 of about 266,537 (289)

Characterization of [³H]‐prostaglandin E₂ binding to prostaglandin EP₄ receptors expressed with Semliki Forest virus [PDF]

, 1997
Fiona H. Marshall, Kalpana Patel, Kenneth Lundström, Janet Camacho, Steven M. Foord, Melanie G. Lee   +5 more
openalex   +1 more source

Inflammatory bowel disease and metabolic reprogramming: From pathological mechanisms to targeted interventions

Interdisciplinary Medicine, EarlyView.
This review explores the role of metabolic reprogramming in inflammatory bowel disease (IBD) by focusing on immune and epithelial cell metabolism, microbial metabolites, and their impact on inflammation. It discusses emerging metabolic therapies and emphasizes the importance of personalized microbiota‐targeted approaches to improve clinical outcomes in
Zemin Tian, Yinde Huang, Ying Wang, Chenyu Zhao, Zhaokai Zhou, Hua Yang, Yuan Qiu   +6 more
wiley   +1 more source

Prostaglandin E₂ (PGE₂) in tissue regeneration: Its role and therapeutic strategies. [PDF]

EXCLI J
Wang W, Pan K, Yang J, Li Z.
europepmc   +1 more source

Novel, Brain-Permeable, Cross-Species Benzothiazole Inhibitors of Microsomal Prostaglandin E Synthase-1 (mPGES-1) Dampen Neuroinflammation In Vitro and In Vivo. [PDF]

ACS Pharmacol Transl Sci, 2023
Sluter MN, Bhuniya R, Yuan X, Ramaraju A, Chen Y, Yu Y, Parmar KR, Temrikar ZH, Srivastava A, Meibohm B, Jiang J, Yang CY.   +11 more
europepmc   +1 more source

Non‐invasive and efficient diabetic retinal mitochondrial repair nanoplatform based on engineered endothelial mitochondrial‐derived vesicles with dynamic integrated stress response modulation

Interdisciplinary Medicine, EarlyView.
Under hyperglycemic conditions, mitochondrial dysfunction in retinal endothelial cells triggers excessive reactive oxygen species/reactive nitrogen species production, barrier protein degradation, and endothelial barrier breakdown in diabetic retinopathy.
Siyu Gui, Jie Gao, Tianchang Tao, Peng Wang, Zhihao Huang, Yuyang She, Jiajie Li, Jingwan Su, Zhe Lu, Jianchao Qiao, Song Wang, Xiaodong Sun, Mohan Li   +12 more
wiley   +1 more source

Prostaglandin E₂ stimulates opposing effects on inner and outer blood-retina barrier function. [PDF]

Front Pharmacol
Stark AK, Gilmartin AR, Ontko CD, Smith TE, Beall AL, McCollum GW, Penn JS.   +6 more
europepmc   +1 more source

Prostaglandin E-major urinary metabolite diagnoses mucosal healing in patients with ulcerative colitis in remission phase. [PDF]

J Gastroenterol Hepatol, 2022
Sakurai T, Akita Y, Miyashita H, Miyazaki R, Maruyama Y, Saito T, Shimada M, Yamasaki T, Arhihiro S, Kato T, Matsuura T, Ikegami M, Okayasu I, Saruta M.   +13 more
europepmc   +1 more source

Aminothiazole-Featured Pirinixic Acid Derivatives As Dual 5-Lipoxygenase and Microsomal Prostaglandin E₂Synthase-1 Inhibitors with Improved Potency and Efficiency in Vivo

, 2013
Thomas Hanke, Friederike Dehm, Stefanie Liening, Sven-Desiderius Popella, Jonas Maczewsky, Max Pillong, Jens Kunze, Christina Weinigel, Dagmar Barz, Astrid Kaiser, Mario Wurglics, Michael Lämmerhofer, Gisbert Schneider, Lidia Sautebin, Manfred Schubert‐Zsilavecz, Oliver Werz   +15 more
openalex   +1 more source

The Application Value of Transvaginal Three‐Dimensional Ultrasonography in the Diagnosis of Adenomyosis of the Uterus

Journal of Clinical Ultrasound, EarlyView.
In this study, 3D‐TVS measurements of the uterine junction zone (JZ) in 120 patients showed that a JZmax threshold of ≥ 0.45 cm yielded 77% sensitivity and 89% specificity for adenomyosis diagnosis. Notably, JZ thickness varies minimally with age, demonstrating its stability and excellent diagnostic performance.
Mengyu Li, Zhen Zong, Xiaoman Wang, Hebin Zhang   +3 more
wiley   +1 more source

Targeting prostaglandin E₂ receptor 2 in Schwann cells inhibits inflammatory pain but not inflammation. [PDF]

Nat Commun
Nassini R, Landini L, Marini M, Chieca M, Souza Monteiro de Araújo D, Montini M, Pensieri P, Abruzzese VD, De Siena G, Zhang J, Bellantoni E, De Giorgi V, Romitelli A, Brancolini G, Tonello R, Peach CJ, Mastricci A, Scuffi I, Tesi M, Jensen DD, Schmidt BL, Bunnett NW, De Logu F, Geppetti P.   +23 more
europepmc   +1 more source