Results 21 to 30 of about 266,537 (289)

Prostaglandin cyclooxygenase products but not thromboxane A2 are involved in the pathogenesis of ewthromelalgia in thrombocythaemia

Mediators of Inflammation, 1993
Fluid of artificial blisters from erythromelalgic skin areas in primary thrombocythaemia contained a high amount of prostaglandin-E-like activity. Dazoxiben did not alleviate the erythromelalgia in patients with primary thrombocythaemia despite complete ...
J. J. Michiels, F. J. Zijlstra
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

, 2006
We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C., Brown, Gregory C., Cenko, S. Bradley, Dolan, Stephen, Filippenko, Alexei V., Fruchter, Andrew S., Greiner, Jochen, Horesh, Assaf, Hounsell, Rebekah A., Levan, Andrew J., O'Brien, Paul T., Page, Kim L., Pasham, Dheeraj R., Rau, Arne, Tanvir, Nial R., Wiersema, Klaas   +15 more
core   +2 more sources

Microsomal prostaglandin E synthase-1 is a critical factor in dopaminergic neurodegeneration in Parkinson's disease

Neurobiology of Disease, 2019
Parkinson's disease (PD) is a neurodegenerative disorder of uncertain pathogenesis characterized by the loss of nigrostriatal dopaminergic neurons. Although increased production of prostaglandin E2 (PGE2) has been implicated in tissue damage in several ...
Yuri Ikeda-Matsuo, Hajime Miyata, Tomoko Mizoguchi, Eisaku Ohama, Yasuhito Naito, Satoshi Uematsu, Shizuo Akira, Yasuharu Sasaki, Mitsuo Tanabe   +8 more
doaj   +1 more source

Ciprofloxacin reduces the stimulation of prostaglandin E2 output by interleukin-1 in human tendon-derived cells [PDF]

, 2003
Fluoroquinolone antibiotics such as ciprofloxacin can induce tendon pathology and have various effects on tendon-derived cells in culture. We are investigating whether ciprofloxacin modifies signalling responses in tendon cells.
Corps, AN, Curry, VA, Dutt, D, Harrall, RL, Hazleman, BL, Riley, GP   +5 more
core   +1 more source

The effect of agility exercise on eicosanoid excretion, oxidant status, and plasma lactate in dogs

BMC Veterinary Research, 2012
Background The objective was to determine the effects of agility exercise on dogs of different skill levels with respect to urinary eicosanoids, urinary 15F2t-isoprostane (lipid peroxidation marker) and hematological/biochemical changes in plasma ...
Baltzer Wendy I, Firshman Anna M, Stang Bernadette, Warnock Jennifer J, Gorman Elena, McKenzie Erica C   +5 more
doaj   +1 more source

Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-blind Controlled Study

Journal of Pharmacy & Pharmaceutical Sciences, 2021
Purpose: Prostaglandins play a pivotal role in modulating hair growth cycle. Prostaglandin F2α and prostaglandin E have stimulating and prostaglandin D has inhibitory effects on hair follicle.
Delaram Hossein Mostafa, Aniseh Samadi, Somayeh Niknam, Saman Ahmad Nasrollahi, Alexandre Guishard, Alireza Firooz   +5 more
doaj   +1 more source

Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]

, 2008
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico, Brenneis, Christian, Coste, Ovidiu, Geisslinger, Gerd, Marian, Claudiu, Pierre, Sandra, Popp, Laura, Schmidt, Helmut, Scholich, Klaus   +8 more
core   +1 more source

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

Frontiers in Aging Neuroscience, 2019
Alzheimer’s disease (AD) is reportedly associated with the accumulation of calcium ions (Ca2+), and this accumulation is responsible for the phosphorylation of tau.
Long-Long Cao, Pei-Pei Guan, Yun-Yue Liang, Xue-Shi Huang, Pu Wang   +4 more
doaj   +1 more source

Cardiosphere-derived cells suppress allogeneic lymphocytes by production of PGE2 acting via the EP4 receptor [PDF]

, 2018
derived cells (CDCs) are a cardiac progenitor cell population, which have been shown to possess cardiac regenerative properties and can improve heart function in a variety of cardiac diseases. Studies in large animal models have predominantly focussed on
A Augello, AJ Nauta, AJ Poncelet, AJ White, AS Boyd, B Hegyi, B Nadal-Ginard, C Basso, C Boriesson, C Liang, CH Chen, CY Xiao, D Carrade, D Pinheiro, DR Davis, DY Nah, E Ingulli, EM Oxford, G Couto de, G Wess, G Wess, GO Ramirez-Yañez, H Kanazawa, H Takeyama, I Chimenti, JA Dixon, JG Bartolucci, JM Angles, JW Kang, K Blanc Le, K Malliaras, K Malliaras, K Sato, KM Meurs, L Cambier, L Grigorian-Shamagian, L Lauden, L Öberg, LC Dutton, LJ Kennedy, M Haidar, MA Aminzadeh, MD Nicola, ME Bernardo, ME Campian, MM Duffy, MT Hensley, MT Hensley, N Kvirkvelia, O Campuzano, P Ross, PV Johnston, Q Guan, R Gallet, R Meisel, R Ramasamy, RR Makkar, S Aggarwal, S Simpson, SJ Jansen of Lorkeers, SR Houser, ST Lee, T Maślanka, TL Lynch, TS Li, WS Lee, Y Ding, Y Sun, YC Hsueh, Z Yan   +69 more
core   +2 more sources

Microsomal prostaglandin E synthase-1 in rheumatic diseases

Frontiers in Pharmacology, 2011
Microsomal prostaglandin E synthase-1 (mPGES-1) is a well recognized target for the development of novel anti-inflammatory drugs that can reduce symptoms of inflammation in rheumatic diseases and other inflammatory conditions. In this review, we focus on
Marina eKorotkova, Marina eKorotkova, Per Johan Jakobsson   +2 more
doaj   +1 more source