Results 21 to 30 of about 234,749 (337)

Clinical Significance of Prostaglandins in the Formation of Courses of Bacterial Intestinal Infections in Children

open access: yesZdorovʹe Rebenka, 2015
The levels of prostaglandin E and prostaglandin F2α in the blood serum of infants with bacterial intestinal infections have been investigated. The connection between increased indexes during acute phase of the disease and the type of its course has been ...
T.S. Zharkova
doaj   +1 more source

Microsomal prostaglandin E synthase-1: the inducible synthase for prostaglandin E2.

open access: yesArthritis research & therapy, 2005
Microsomal prostaglandin E synthase-1 (mPGES-1) is an inducible enzyme that catalyzes the conversion of prostaglandin (PG)H2 to PGE2. Proinflammatory stimuli markedly increase levels of mPGES-1 expression both in vivo and in vitro. mPGES-1 knockout studies and animal models of inflammatory arthritis also provide a strong basis for the contribution of ...
Seetha U. Monrad   +2 more
openaire   +3 more sources

Prostaglandin cyclooxygenase products but not thromboxane A2 are involved in the pathogenesis of ewthromelalgia in thrombocythaemia

open access: yesMediators of Inflammation, 1993
Fluid of artificial blisters from erythromelalgic skin areas in primary thrombocythaemia contained a high amount of prostaglandin-E-like activity. Dazoxiben did not alleviate the erythromelalgia in patients with primary thrombocythaemia despite complete ...
J. J. Michiels, F. J. Zijlstra
doaj   +1 more source

Calcium Ions Stimulate the Hyperphosphorylation of Tau by Activating Microsomal Prostaglandin E Synthase 1

open access: yesFrontiers in Aging Neuroscience, 2019
Alzheimer’s disease (AD) is reportedly associated with the accumulation of calcium ions (Ca2+), and this accumulation is responsible for the phosphorylation of tau.
Long-Long Cao   +4 more
doaj   +1 more source

The effect of agility exercise on eicosanoid excretion, oxidant status, and plasma lactate in dogs

open access: yesBMC Veterinary Research, 2012
Background The objective was to determine the effects of agility exercise on dogs of different skill levels with respect to urinary eicosanoids, urinary 15F2t-isoprostane (lipid peroxidation marker) and hematological/biochemical changes in plasma ...
Baltzer Wendy I   +5 more
doaj   +1 more source

Efficacy of Cetirizine 1% Versus Minoxidil 5% Topical Solution in the Treatment of Male Alopecia: A Randomized, Single-blind Controlled Study

open access: yesJournal of Pharmacy & Pharmaceutical Sciences, 2021
Purpose: Prostaglandins play a pivotal role in modulating hair growth cycle. Prostaglandin F2α and prostaglandin E have stimulating and prostaglandin D has inhibitory effects on hair follicle.
Delaram Hossein Mostafa   +5 more
doaj   +1 more source

Multi‐omics analyses reveal the interaction between colonic microbiota and host in Min and Yorkshire pigs

open access: yesAnimal Research and One Health, EarlyView., 2023
In the present study, we created the weight gain models with Min and Yorkshire pigs and conducted the metagenomics and metabolomics of colon contents and transcriptomics of colon tissue. Further, we revealed the characteristics and functions of the colonic microbiota in Min and Yorkshire pigs and analyzed their interactions with the host. Overall, this
Xiaoyu Huang   +6 more
wiley   +1 more source

Microsomal prostaglandin E synthase-1 in rheumatic diseases

open access: yesFrontiers in Pharmacology, 2011
Microsomal prostaglandin E synthase-1 (mPGES-1) is a well recognized target for the development of novel anti-inflammatory drugs that can reduce symptoms of inflammation in rheumatic diseases and other inflammatory conditions. In this review, we focus on
Marina eKorotkova   +2 more
doaj   +1 more source

Tumor-Induced T Cell Polarization by Schwann Cells

open access: yesCells, 2022
Nerve-cancer crosstalk resulting in either tumor neurogenesis or intratumoral neurodegeneration is critically controlled by Schwann cells, the principal glial cells of the peripheral nervous system.
Galina V. Shurin   +4 more
doaj   +1 more source

Antinociceptive activity of the S1P-receptor agonist FTY720 [PDF]

open access: yes, 2008
FTY720 is a novel immunosuppressive drug that inhibits the egress of lymphocytes from secondary lymphoid tissues and thymus. In its phosphorylated form FTY720 is a potent S1P receptor agonist.
Angioni, Carlo Federico   +8 more
core   +1 more source

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