Results 21 to 30 of about 346,955 (321)
The role of PAF in immunopathology: From immediate hypersensitivity reactions to fungal defense
BioFactors, Volume 48, Issue 6, Page 1217-1225, November/December 2022., 2022 Abstract Platelet‐activating factor (PAF, 1‐alkyl‐2‐acetyl‐sn‐glycero‐3‐phosphorylcholine) was discovered when the mechanisms involved in the deposition of immune complex in tissues were being scrutinized in the experimental model of rabbit serum sickness.
Mariano Sánchez Crespo +2 more
wiley +1 more source
An extension of a theorem of Zermelo [PDF]
Bull. symb. log 25 (2019) 208-212, 2018 We show that if (M,E,E') satisfies the first order Zermelo-Fraenkel axioms of set theory when the membership relation is E and also when the membership relation is E', and in both cases the formulas are allowed to contain both E and E', then (M,E) and (M,E') are isomorphic, and the isomorphism is definable in (M,E,E').
arxiv +1 more source
Frontiers in Aging Neuroscience, 2019 Alzheimer’s disease (AD) is reportedly associated with the accumulation of calcium ions (Ca2+), and this accumulation is responsible for the phosphorylation of tau.
Long-Long Cao +4 more
doaj +1 more source
Journal of Pharmacy & Pharmaceutical Sciences, 2021 Purpose: Prostaglandins play a pivotal role in modulating hair growth cycle. Prostaglandin F2α and prostaglandin E have stimulating and prostaglandin D has inhibitory effects on hair follicle.
Delaram Hossein Mostafa +5 more
doaj +1 more source
Exosomes and their roles in the chemoresistance of pancreatic cancer
Cancer Medicine, Volume 11, Issue 24, Page 4979-4988, December 2022., 2022 Despite the development of multiple promising chemotherapeutic agents as recommended first‐line treatment for PC, the therapeutic efficacy is largely limited by unwanted drug resistance.Exploring the relation between exosomes and chemoresistance may be conducive to understanding molecular mechanisms and taking effective measures to reduce the ...
Yubin Pan +4 more
wiley +1 more source
Microsomal prostaglandin E synthase-1 in rheumatic diseases
Frontiers in Pharmacology, 2011 Microsomal prostaglandin E synthase-1 (mPGES-1) is a well recognized target for the development of novel anti-inflammatory drugs that can reduce symptoms of inflammation in rheumatic diseases and other inflammatory conditions. In this review, we focus on
Marina eKorotkova +2 more
doaj +1 more source
Tumor-Induced T Cell Polarization by Schwann Cells
Cells, 2022 Nerve-cancer crosstalk resulting in either tumor neurogenesis or intratumoral neurodegeneration is critically controlled by Schwann cells, the principal glial cells of the peripheral nervous system.
Galina V. Shurin +4 more
doaj +1 more source
Metabolism of prostaglandins E, A, and C in serum
Journal of Biological Chemistry, 1975 Three prostaglandin-metabolizing enzymes were detected in human serum. One enzyme was a dehydrase that converted prostaglandin E to prostaglandin A, the second was a prostaglandin A isomerase that converted prostaglandin A to prostaglandin C and the third was a prostaglandin C isomerase that converted prostaglandin C to prostaglandin B.
L Levine, H Polet
openaire +3 more sources
Molecules, 2014 Microsomal prostaglandin E2 synthase-1 (mPGES-1), an inducible enzyme that converts prostaglandin H2 (PGH2) to prostaglandin E2 (PGE2), plays an important role in a variety of diseases.
Bo Wei +12 more
doaj +1 more source
FEBS Letters, EarlyView.Metabolic dysfunction‐associated steatotic liver disease (MASLD) affects nearly one‐third of the global population and poses a significant risk of progression to cirrhosis or liver cancer. Here, we discuss the roles of hepatic dendritic cell subtypes in MASLD, highlighting their distinct contributions to disease initiation and progression, and their ...
Camilla Klaimi +3 more
wiley +1 more source