Differential Stem and Progenitor Cell Trafficking by Prostaglandin E2
Nature, 2013 To maintain lifelong production of blood cells, haematopoietic stem cells (HSCs) are tightly regulated by inherent programs and extrinsic regulatory signals received from their microenvironmental niche.
Jonathan Hoggatt +20 more
semanticscholar +1 more source
Regional distribution of the prostaglandin E2 receptor EP1 in the rat brain: accumulation in Purkinje cells of the cerebellum [PDF]
Journal of Molecular Neuroscience 27(3): 303-310 (2005), 2007 Prostaglandin E2 (PGE2), is a major prostanoid produced by the activity of cyclooxygenases (COX) in response to various physiological and pathological stimuli. PGE2 exerts its effects by activating four specific E-type prostanoid receptors (EP1, EP2, EP3, and EP4).
arxiv
B(E2) Predictions for Even-Even Nuclei in the Differential Equation Model [PDF]
, 2014 We use the recently developed Differential Equation Model for the reduced electric quadrupole transition probability B(E2) for predicting its values for a wide range of even-even nuclides almost throughout the nuclear landscape from Neon to Californium.
arxiv +1 more source
Cyclooxygenase inhibition lowers prostaglandin E2 release from articular cartilage and reduces apoptosis but not proteoglycan degradation following an impact load in vitro [PDF]
, 2007 This study investigated the release of prostaglandin E2 (PGE2) from cartilage following an impact load in vitro and the possible chondroprotective effect of cyclooxygenase-2 (COX-2) inhibition using non-steroidal anti-inflammatory drugs (NSAIDs)
Aspden, Richard M, Jeffrey, Janet E
core +2 more sources
Prostaglandin E2 induces ovulation in prepubertal mice
Brazilian Journal of Veterinary Research and Animal Science, 2021 The objective of this study was to determine the ability of prostaglandin E2 (PGE2) to induce ovulation and expression of PGE2 receptor (EP2 and EP4) and COX genes (COX-1 and COX-2) in the ovary and pituitary of prepubertal mice.
Jéssica de Souza Andrade +6 more
doaj
Post-ischaemic treatment with the cyclooxygenase-2 inhibitor nimesulide reduces blood-brain barrier disruption and leukocyte infiltration following transient focal cerebral ischaemia in rats [PDF]
Journal of Neurochemistry 100(4): 1108-1120 (2007), 2007 Several studies suggest that cyclooxygenase (COX)-2 plays a pivotal role in the progression of ischaemic brain damage. In the present study, we investigated the effects of selective inhibition of COX-2 with nimesulide (12 mg/kg) and selective inhibition of COX-1 with valeryl salicylate (VAS, 12-120 mg/kg) on prostaglandin E2 (PGE2) levels ...
arxiv
Leveraging Large Text Corpora for End-to-End Speech Summarization [PDF]
arXiv, 2023 End-to-end speech summarization (E2E SSum) is a technique to directly generate summary sentences from speech. Compared with the cascade approach, which combines automatic speech recognition (ASR) and text summarization models, the E2E approach is more promising because it mitigates ASR errors, incorporates nonverbal information, and simplifies the ...
arxiv
THE ROLE OF PROSTAGLANDIN (PGE2) IN ALVEOLAR BONE DESTRUCTION [PDF]
, 2015 Inflammation chronic diseases in gingiva and periodontium tissue cause destruction of alveolar bone. Periodontopathy bacteria cause periodontal tissue destruction by host cell activating system, such as prostaglandin.
Mohammed, Asam Khalifa
core +1 more source
Prostaglandin E2 functions as a luteotrophic factor in the dog.
Reproduction, 2013 The luteal phase in dogs is governed by many poorly understood regulatory mechanisms. Functioning of the corpus luteum (CL) is unaffected by hysterectomy.
M. Kowalewski +4 more
semanticscholar +1 more source
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat [PDF]
Journal of Pharmacology and Experimental Therapeutics 323(2):
488-498 (2007), 2007 Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-a (TNF-a) is involved in BBB injury and edema formation through a mechanism involving matrix metalloproteinase (MMP) upregulation. There is emerging evidence
arxiv