Results 41 to 50 of about 373,954 (298)

Involvement of the endogenous nitric oxide signalling system in bradykinin receptor activation in rat submandibular salivary gland [PDF]

open access: yes, 2000
Biochemical signalling events coupled to the bradykinin B2-receptor subtype, related to nitric oxide and prostaglandin E2 generation were studied in rat submandibular gland.
Borda, Enri Santiago   +2 more
core   +1 more source

Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium

open access: yesEMBO Journal, 2017
Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
H. Miyoshi   +7 more
semanticscholar   +1 more source

Pharmacological Characterization of the Microsomal Prostaglandin E2 Synthase-1 Inhibitor AF3485 In Vitro and In Vivo

open access: yesFrontiers in Pharmacology, 2020
RationaleThe development of inhibitors of microsomal prostaglandin (PG)E2 synthase-1 (mPGES-1) was driven by the promise of attaining antiinflammatory agents with a safe cardiovascular profile because of the possible diversion of the accumulated ...
Luigia Di Francesco   +12 more
doaj   +1 more source

Plant Hormone Salicylic Acid Produced by a Malaria Parasite Controls Host Immunity and Cerebral Malaria Outcome. [PDF]

open access: yesPLoS ONE, 2015
The apicomplexan parasite Toxoplasma gondii produces the plant hormone abscisic acid, but it is unclear if phytohormones are produced by the malaria parasite Plasmodium spp., the most important parasite of this phylum.
Ryuma Matsubara   +6 more
doaj   +1 more source

Prostaglandin E2 constrains systemic inflammation through an innate lymphoid cell–IL-22 axis

open access: yesScience, 2016
A prostaglandin barrier to inflammation Blood-borne bacterial infections and severe trauma can send the immune system into overdrive, causing it to pump out inflammatory mediators, sometimes at lethal doses. Duffin et al.
R. Duffin   +23 more
semanticscholar   +1 more source

Phospholipase A2-activating protein is associated with a novel form of leukoencephalopathy [PDF]

open access: yes, 2016
Leukoencephalopathies are a group of white matter disorders related to abnormal formation, maintenance, and turnover of myelin in the central nervous system.
Anikster, Y   +26 more
core   +1 more source

Prostaglandin E2 As a Modulator of Viral Infections

open access: yesFrontiers in Physiology, 2017
Viral infections are a major cause of infectious diseases worldwide. Inflammation and the immune system are the major host defenses against these viral infection.
Willem J Sander, H. O’Neill, C. Pohl
semanticscholar   +1 more source

Acute Hemoperitoneum after Administration of Prostaglandin E2 for Induction of Labour

open access: yesCase Reports in Obstetrics and Gynecology, 2015
Prostaglandin E2 is widely used in obstetrics and is thought to be relatively safe for cervical ripening and induction of labour. Here we present a case in which acute hemoperitoneum was observed after administration of prostaglandin E2 in a pregnant ...
Zhenyu Zhang, Jiangyan Lou
doaj   +1 more source

Reciprocal interactions between prostaglandin E2- and estradiol-dependent signaling pathways in the injured zebra finch brain

open access: yesJournal of Neuroinflammation, 2017
Background Astrocytic aromatization and consequent increases in estradiol are neuroprotective in the injured brain. In zebra finches, cyclooxygenase-activity is necessary for injury-induced aromatase expression, and increased central estradiol lowers ...
Alyssa L. Pedersen, Colin J. Saldanha
doaj   +1 more source

Gastroprotective effect of Berberis vulgaris on ethanol-induced gastric mucosal injury: Histopathological evaluations [PDF]

open access: yesAvicenna Journal of Phytomedicine, 2022
Objective: Modern treatment of peptic ulcers includes antibacterial and gastroprotective medications. However, current anti-ulcer drugs possess severe side effects.
Marina Kapitonova   +8 more
doaj   +1 more source

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