Results 101 to 110 of about 277,845 (352)
Proceedings of the National Academy of Sciences of the United States of America, 1999 Mechanisms leading to down-regulation of activated microglia and astrocytes are poorly understood, in spite of the potentially detrimental role of activated glia in neurodegeneration.
T. Petrova, K. Akama, L. Eldik
semanticscholar +1 more source
Challenges and Limitations of Clinical Trials on Labor Induction: A Review of the Literature
American Journal of Perinatology Reports, 2018 Induction of labor is a common obstetric procedure performed in nearly a quarter of all deliveries in the United States. Pharmacological (prostaglandins, oxytocin) and/or mechanical methods (balloon catheters) are commonly used for labor induction ...
Oscar A. Viteri, Baha M. Sibai
doaj +1 more source
Mathematical models for the EP2 and EP4 signaling pathways and their crosstalk [PDF]
arXivThe G-protein coupled receptors EP2 and EP4 both transduce the signal of the lipid messenger Prostaglandin E2 (PGE2). Changes in the cell response to PGE2 can have important effects on immunity and development of diseases, however, a thorough understanding of the EP2-EP4 receptors' signaling pathways is lacking.
arxiv
Chemistry &Biodiversity, EarlyView.ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves +3 more
wiley +1 more source
Journal of Lipid Research, 2014 Arachidonic acid (AA) is a major PUFA that has been implicated in the regulation of adipogenesis. We examined the effect of a short exposure to AA at different stages of 3T3-L1 adipocyte differentiation.
Evanthia Nikolopoulou +6 more
doaj
Bioactives From Brown Algae: Antioxidant, Anti‐Inflammatory, Anticancer, and Antimicrobial Potential
ChemBioEng Reviews, EarlyView.This review explores key bioactives in brown algae and their antioxidant, anti‐inflammatory, anticancer, and antimicrobial properties. Covering studies from 2014 to 2024, it highlights their relevance in pharmaceuticals, nutraceuticals, cosmetics, and foods, while addressing challenges and future directions to unlock their full potential.
Irvin Fonseca‐Barahona +2 more
wiley +1 more source
Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping
Journal of Lipid Research, 2019 The eicosanoids are a family of lipid mediators of pain and inflammation involved in multiple pathologies, including asthma, hypertension, cancer, atherosclerosis, and neurodegenerative diseases.
Cristina Gómez +7 more
doaj
The Structure of Prostaglandin E, F1 and F2. [PDF]
, 1962 Sune Bergström +5 more
openalex +1 more source
Lipid Metabolism and Immune Function: Chemical Tools for Insights into T‐Cell Biology
ChemBioChem, EarlyView.This review explores how lipids regulate immune responses, particularly in T‐cell function. Advances in metabolomics and proteomics provide insights into lipid‐mediated immunity. Fluorescent lipids enable single‐cell analysis of lipid uptake and metabolism.
Luuk Reinalda +2 more
wiley +1 more source
Regulation of Dendritic Cell Function by Ermiaosan via the EP4-cAMP-CREB Signaling Pathway [PDF]
arXivErmiao San (EMS), a traditional Chinese medicine composed of Atractylodes macrocephala and Cortex Phellodendron, has demonstrated therapeutic efficacy in rheumatoid arthritis (RA). Studies suggest that EMS modulates dendritic cell (DC) maturation in adjuvant arthritis (AA) rats, though the precise mechanisms remain unclear.
arxiv