Results 101 to 110 of about 177,517 (296)
Frontiers in Endocrinology, 2019 The current study aimed to isolate, culture and characterize small (SLC) and large (LLC) steroidogenic cells from the corpora lutea (CL) of non-pregnant domestic cats.
Michał M. Hryciuk +3 more
doaj +1 more source
Advanced Science, EarlyView.Producing MSCs on rigid culture substrates induces a scar‐making phenotype, jeapordizing therapeutic success. ‘Tissue‐soft’ surfaces prevent MSC fibrogenesis and preserve regenerative traits. An epigenetic network, driven by HOXA11 and SALL1, maintains ‘soft memory’ by keeping chromatin open in relaxed MSCs, promoting anti‐fibrotic programs.
Fereshteh Sadat Younesi +7 more
wiley +1 more source
Angewandte Chemie, EarlyView.Parallel mass spectrometry imaging acquires high mass resolution and tandem mass spectrometry images from 108 isolation windows in a single run. Spatial similarity networking clusters product ions by spatial distribution, enabling annotation of isomers and isobars as demonstrated for phospholipids and oxidized cholesterol in mouse and human brain ...
Varun V. Sharma +5 more
wiley +2 more sources
Advanced Science, EarlyView.Mesenchymal stromal cells (MSCs) show promise for treating immune‐related disorders through immunomodulation and tissue regeneration. This review gives a brief overview of current clinical approval of MSC therapies. It also discussed how bioengineering, including genetic modification, biomaterial delivery, extracellular vesicles, and iPSC‐derived MSCs,
Sichen Yang +6 more
wiley +1 more source
Prostaglandin E2 promotes intestinal repair through an adaptive cellular response of the epithelium [PDF]
, 2017 Adaptive cellular responses are often required during wound repair. Following disruption of the intestinal epithelium, wound‐associated epithelial (WAE) cells form the initial barrier over the wound.
Lai, Chin-Wen +7 more
core +2 more sources
The Emerging Parkinson's Disease Oxylipin‐Ome
Advanced Science, EarlyView.ABSTRACT Parkinson Disease (PD) is increasingly considered a proteinopathy and lipidopathy. This proteinopathy+lipidopathy paradigm has been further refined to a fatty acid (FA)‐opathy, centering dysregulated FA metabolism as fundamental in PD lipid dysfunction.
Julia C. Kelliher, Saranna Fanning
wiley +1 more source
Quantitative metabolic profiling of urinary eicosanoids for clinical phenotyping
Journal of Lipid Research, 2019 The eicosanoids are a family of lipid mediators of pain and inflammation involved in multiple pathologies, including asthma, hypertension, cancer, atherosclerosis, and neurodegenerative diseases.
Cristina Gómez +7 more
doaj +1 more source
ESCRT‐Mimetic Nanodegrader Targets STING for Anti‐Inflammatory Therapy
Advanced Science, EarlyView.A nanoplatform‐enabled targeted protein degradation strategy is presented to regulate aberrant STING signaling. STING‐ATTEC induces selective autophagic degradation of STING via formation of a STING–ATTEC–LC3 ternary complex, while the cationic FA‐LNP+ system enhances LC3 generation and targeted delivery. Together, this synergistic approach efficiently
Fuyuan Zhou +9 more
wiley +1 more source
NSAIDs and Acute Pancreatitis: A Systematic Review
Pharmaceuticals, 2010 The resulting pain is the main symptom of acute pancreatitis and it should be alleviated as soon as possible. NSAIDs are the first line therapy for pain and they are generally administered to acute pancreatitis patients upon admission to the hospital. In
Roberto Corinaldesi +2 more
doaj +1 more source
Postoperative Pain After The Use Of A Dexamethasone Rinse As An Irrigant Prior To Obturation [PDF]
, 2013 Purpose: The purpose of this randomized, double-blind pilot study was to determine the effect of dexamethasone on post-operative pain when used as an intracanal rinse prior to obturation.
Tarabishy, Kenan
core +1 more source