Results 11 to 20 of about 114,931 (296)

Prostaglandins in Induction of Labour

open access: yesNational Journal of Medical Research, 2022
Prostaglandins are naturally occurring hormones that play a significant role in the commencement of labour. Prostaglandins have been utilised in clinical practise to ripen the cervix and elicit uterine contractions synthetically since the 1960s.
Harsh Shah
doaj   +1 more source

Misidentification of prostamides as prostaglandins

open access: yesJournal of Lipid Research, 2005
Prostaglandins and endogenous cannabinoid metabolites share the same lipid backbone with differing polar head groups at exactly the position through which a large molecule is attached to provide antigenicity and thus raise antisera.
Michelle Glass   +3 more
doaj   +2 more sources

Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases [PDF]

open access: yesMediators of Inflammation, 2012
Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role.
Isabel Vieira de Assis Lima   +4 more
doaj   +2 more sources

Lactones in the Synthesis of Prostaglandins and Prostaglandin Analogs [PDF]

open access: yesInternational Journal of Molecular Sciences, 2021
In the total stereo-controlled synthesis of natural prostaglandins (PGs) and their structural analogs, a vast class of compounds and drugs, known as the lactones, are encountered in a few key steps to build the final molecule, as: δ-lactones, γ-lactones, and 1,9-, 1,11-, and 1,15-macrolactones.
Constantin Tănase   +2 more
openaire   +3 more sources

PROSTAGLANDINS

open access: yesThe Lancet, 1968
Observations from 1930 to 1934 have indicated autopharmacological effects of human seminal fluid. The active principle was shown to be an unsaturated lipid‐soluble acid. After isolation in 1960 of two closely related compounds, the chemical constitution was established.
openaire   +6 more sources

Effect of prostaglandins and beta blockers on progression of hypertensive and normotensive glaucomas

open access: yes, 2021
Aim. The aim of the study was to evaluate the progression of changes in the visual fields in patients with hypertensive glaucoma (HTG) and normotensive glaucoma (NTG) following administration of prostaglandins and beta blockers, as well as also in NTG ...
Klara Maresova   +3 more
core   +1 more source

Outpatient vs inpatient induction of labor with oral misoprostol: A retrospective study

open access: yesActa Obstetricia et Gynecologica Scandinavica, 2023
Introduction Induction of labor is one of the most common obstetrical procedures today, with a successively rising rate. With a limited number of hospital beds, the option of starting induction at home has gained increasing attention.
Natalie Hallén   +3 more
doaj   +1 more source

COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury

open access: yesAntioxidants, 2022
Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) injury (IRI), decreasing necrosis, reducing reactive oxygen species (ROS ...
Marina Fuertes-Agudo   +7 more
doaj   +1 more source

Modulation of Enzyme-Catalyzed Synthesis of Prostaglandins by Components Contained in Kidney Microsomal Preparations

open access: yesMolecules, 2021
In the kidney, prostaglandins formed by cyclooxygenase 1 and 2 (COX-1 and COX-2) play an important role in regulating renal blood flow. In the present study, we report our observations regarding a unique modulatory effect of renal microsomal preparation ...
Hyoung-Woo Bai   +4 more
doaj   +1 more source

Metformin attenuates high-fat diet induced metabolic syndrome related osteoarthritis through inhibition of prostaglandins

open access: yesFrontiers in Cell and Developmental Biology, 2023
High-fat diet induces bone marrow inflammation and osteoarthritis phenotype in knee joint, but the underlying mechanisms is unknown. Here, we report that high-fat diet induces aberrant bone formation and cartilage degeneration in knee joint ...
Xiaonan Liu   +7 more
doaj   +1 more source

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