Results 21 to 30 of about 114,931 (296)

Interleukin and prostaglandin status of patients with shingles depending on the severity of the disease

open access: yesPatologìâ, 2020
Aim. The aim of the work is to study the interleukin and prostaglandin status of patients with shingles depending on the severity of the disease. Materials and methods. We examined the blood of 27 patients with shingles, aged from 52 to 69 years, with
O. M. Novytskyi, I. S. Haidash
doaj   +1 more source

Cyclopentenone Prostaglandins: Biologically Active Lipid Mediators Targeting Inflammation

open access: yesFrontiers in Physiology, 2021
Cyclopentenone prostaglandins (cyPGs) are biologically active lipid mediators, including PGA2, PGA1, PGJ2, and its metabolites. cyPGs are essential regulators of inflammation, cell proliferation, apoptosis, angiogenesis, cell migration, and stem cell ...
Bohae Rachel Lee   +2 more
doaj   +1 more source

NSAID : Dari Analgetik-antiinflamasi ke Antineoplasi

open access: yesJournal of Dentistry Indonesia, 2015
Inflammatory mediators, such as prostaglandins and histamines can cause pain. Non steroid anti-inflammatory drugs (NSAIDs) have been indicated to reduce pain on inflammatory conditions.
Gunawan Wibisono
doaj   +1 more source

Chemistry of Prostaglandins and Thromboxanes

open access: yes, 1977
The structures of several prostaglandins were determined during the early 1960’s. First, two biologically active compounds were isolated from sheep vesicular glands; these compounds were called PGE1 and PGF1α (for a review, see Ref. 1). Reduction of PGE1
Granström, E, Elisabeth Granström
core   +1 more source

Metabolism of Prostaglandins

open access: yes, 1977
The major initial steps in the degradation of the prostaglandins are the oxidation of the secondary alcohol group at C-15 and the reduction of the Δ13 double bond (for a recent review, see 1).
Granström, E, Elisabeth Granström
core   +1 more source

Prostaglandins: Key players in immunomodulation of the nervous system

open access: yesNeural Regeneration Research
As a class of bioactive substances that play important roles in a variety of physiological and pathological processes, prostaglandins have attracted increasing research attention.
Ziqin Wang   +8 more
doaj   +1 more source

Effect of prostaglandin analogues on central corneal thickness in patients with glaucoma: A systematic review and meta-analysis with trial sequential analysis

open access: yesIndian Journal of Ophthalmology, 2022
The objective of this meta-analysis was to evaluate the effect of prostaglandin analogues (PGA) on central corneal thickness (CCT) in patients with glaucoma. Key electronic databases were searched for randomized controlled trials (RCTs) involving the CCT
Rajani Kadri   +5 more
doaj   +1 more source

Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection

open access: yesMediators of Inflammation, 2013
Prostaglandins act as mediators of inflammation and, similar to cytokines, function as immune modulators during innate and adaptive immune responses. Therefore, using a pharmacological inhibitor, celecoxib, we investigated the role of prostaglandins in ...
Priscilla Aparecida Tartari Pereira   +8 more
doaj   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska   +13 more
wiley   +1 more source

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