Results 21 to 30 of about 177,517 (296)

COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury

open access: yesAntioxidants, 2022
Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) injury (IRI), decreasing necrosis, reducing reactive oxygen species (ROS ...
Marina Fuertes-Agudo   +7 more
doaj   +1 more source

Modulation of Enzyme-Catalyzed Synthesis of Prostaglandins by Components Contained in Kidney Microsomal Preparations

open access: yesMolecules, 2021
In the kidney, prostaglandins formed by cyclooxygenase 1 and 2 (COX-1 and COX-2) play an important role in regulating renal blood flow. In the present study, we report our observations regarding a unique modulatory effect of renal microsomal preparation ...
Hyoung-Woo Bai   +4 more
doaj   +1 more source

Metformin attenuates high-fat diet induced metabolic syndrome related osteoarthritis through inhibition of prostaglandins

open access: yesFrontiers in Cell and Developmental Biology, 2023
High-fat diet induces bone marrow inflammation and osteoarthritis phenotype in knee joint, but the underlying mechanisms is unknown. Here, we report that high-fat diet induces aberrant bone formation and cartilage degeneration in knee joint ...
Xiaonan Liu   +7 more
doaj   +1 more source

Changes in PGE2 signaling after submandibulectomy alter post–tooth extraction socket healing [PDF]

open access: yes, 2018
Saliva is very important to oral health, and a salivary deficit has been shown to bring serious problems to oral health. There is scant information about the mechanisms through which salivary glands participate in post–tooth extraction socket healing ...
Bozzini, Clarisa   +5 more
core   +1 more source

Interleukin and prostaglandin status of patients with shingles depending on the severity of the disease

open access: yesPatologìâ, 2020
Aim. The aim of the work is to study the interleukin and prostaglandin status of patients with shingles depending on the severity of the disease. Materials and methods. We examined the blood of 27 patients with shingles, aged from 52 to 69 years, with
O. M. Novytskyi, I. S. Haidash
doaj   +1 more source

Cyclosporin A inhibits PGE2 release from vascular smooth muscle cells [PDF]

open access: yes, 1987
The influence of the fungoid undecapeptide cyclosporin A (CyA) on PGE2 release from cultured rat aortic smooth muscle cells was investigated in this study.
Koch, K. M.   +3 more
core   +1 more source

Statin-induced myopathic changes in primary human muscle cells and reversal by a prostaglandin F2 alpha analogue [PDF]

open access: yes, 2020
Statin-related muscle side effects are a constant healthcare problem since patient compliance is dependent on side effects. Statins reduce plasma cholesterol levels and can prevent secondary cardiovascular diseases.
Dittmar, Gunnar   +10 more
core   +1 more source

NSAID : Dari Analgetik-antiinflamasi ke Antineoplasi

open access: yesJournal of Dentistry Indonesia, 2015
Inflammatory mediators, such as prostaglandins and histamines can cause pain. Non steroid anti-inflammatory drugs (NSAIDs) have been indicated to reduce pain on inflammatory conditions.
Gunawan Wibisono
doaj   +1 more source

Cyclopentenone Prostaglandins: Biologically Active Lipid Mediators Targeting Inflammation

open access: yesFrontiers in Physiology, 2021
Cyclopentenone prostaglandins (cyPGs) are biologically active lipid mediators, including PGA2, PGA1, PGJ2, and its metabolites. cyPGs are essential regulators of inflammation, cell proliferation, apoptosis, angiogenesis, cell migration, and stem cell ...
Bohae Rachel Lee   +2 more
doaj   +1 more source

Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases

open access: yesMediators of Inflammation, 2012
Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role.
Isabel Vieira de Assis Lima   +4 more
doaj   +1 more source

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