Results 21 to 30 of about 113,074 (192)
A heterogeneous mixture of F-series prostaglandins promotes sperm guidance in the Caenorhabditis elegans reproductive tract. [PDF]
PLoS Genetics, 2013 The mechanisms that guide motile sperm through the female reproductive tract to oocytes are not well understood. We have shown that Caenorhabditis elegans oocytes synthesize sperm guiding F-series prostaglandins from polyunsaturated fatty acid (PUFA ...
Hieu D Hoang +3 more
doaj +1 more source
eLife, 2021 Receptor-interacting serine/threonine-protein kinase 3 (RIPK3) normally signals to necroptosis by phosphorylating MLKL. We report here that when the cellular RIPK3 chaperone Hsp90/CDC37 level is low, RIPK3 also signals to apoptosis.
Dianrong Li +10 more
doaj +1 more source
Biomedicine Hub, 2022 Introduction: Parenteral prostanoids are the most potent therapies for pulmonary arterial hypertension (PAH) but are associated with complications and lifestyle limitations.
Colin Hinkamp +4 more
doaj +1 more source
Effect of prostaglandins and beta blockers on progression of hypertensive and normotensive glaucomas
, 2021 Aim. The aim of the study was to evaluate the progression of changes in the visual fields in patients with hypertensive glaucoma (HTG) and normotensive glaucoma (NTG) following administration of prostaglandins and beta blockers, as well as also in NTG ...
Klara Maresova +3 more
core +1 more source
Prostaglandin synthesis in rat adrenocortical cells.
Journal of Lipid Research, 1979 The biosynthesis of prostaglandins by isolated rat adrenocortical cells has been studied by determinations of products formed during incubations with labeled arachidonic acid and by radioimmunoassays.
R Chanderbhan +3 more
doaj +1 more source
The Lancet, 1968 Observations from 1930 to 1934 have indicated autopharmacological effects of human seminal fluid. The active principle was shown to be an unsaturated lipid‐soluble acid. After isolation in 1960 of two closely related compounds, the chemical constitution was established.
openaire +6 more sources
Outpatient vs inpatient induction of labor with oral misoprostol: A retrospective study
Acta Obstetricia et Gynecologica Scandinavica, 2023 Introduction Induction of labor is one of the most common obstetrical procedures today, with a successively rising rate. With a limited number of hospital beds, the option of starting induction at home has gained increasing attention.
Natalie Hallén +3 more
doaj +1 more source
Antioxidants, 2022 Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) injury (IRI), decreasing necrosis, reducing reactive oxygen species (ROS ...
Marina Fuertes-Agudo +7 more
doaj +1 more source
Molecules, 2021 In the kidney, prostaglandins formed by cyclooxygenase 1 and 2 (COX-1 and COX-2) play an important role in regulating renal blood flow. In the present study, we report our observations regarding a unique modulatory effect of renal microsomal preparation ...
Hyoung-Woo Bai +4 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2023 High-fat diet induces bone marrow inflammation and osteoarthritis phenotype in knee joint, but the underlying mechanisms is unknown. Here, we report that high-fat diet induces aberrant bone formation and cartilage degeneration in knee joint ...
Xiaonan Liu +7 more
doaj +1 more source