Results 21 to 30 of about 243,841 (348)

COX-2 Expression in Hepatocytes Improves Mitochondrial Function after Hepatic Ischemia-Reperfusion Injury

open access: yesAntioxidants, 2022
Cyclooxygenase 2 (COX-2) is a key enzyme in prostanoid biosynthesis. The constitutive hepatocyte expression of COX-2 has a protective role in hepatic ischemia-reperfusion (I/R) injury (IRI), decreasing necrosis, reducing reactive oxygen species (ROS ...
Marina Fuertes-Agudo   +7 more
doaj   +1 more source

Diurnal rhythm of plasma EPA and DHA in healthy adults [PDF]

open access: yes, 2020
Knowledge of the diurnal variation in circulating omega-3 polyunsaturated fatty acids (n-3 PUFAs) may be an important consideration for the development of dosing protocols designed to optimise tissue delivery of these fatty acids.
Avery, Hannah   +7 more
core   +2 more sources

Modulation of Enzyme-Catalyzed Synthesis of Prostaglandins by Components Contained in Kidney Microsomal Preparations

open access: yesMolecules, 2021
In the kidney, prostaglandins formed by cyclooxygenase 1 and 2 (COX-1 and COX-2) play an important role in regulating renal blood flow. In the present study, we report our observations regarding a unique modulatory effect of renal microsomal preparation ...
Hyoung-Woo Bai   +4 more
doaj   +1 more source

Metformin attenuates high-fat diet induced metabolic syndrome related osteoarthritis through inhibition of prostaglandins

open access: yesFrontiers in Cell and Developmental Biology, 2023
High-fat diet induces bone marrow inflammation and osteoarthritis phenotype in knee joint, but the underlying mechanisms is unknown. Here, we report that high-fat diet induces aberrant bone formation and cartilage degeneration in knee joint ...
Xiaonan Liu   +7 more
doaj   +1 more source

Seminal plasma and prostaglandin E2 up-regulate fibroblast growth factor 2 expression in endometrial adenocarcinoma cells via E-series prostanoid-2 receptor-mediated transactivation of the epidermal growth factor receptor and extracellular signal-regulated kinase pathway [PDF]

open access: yes, 2006
We report a multiwavelength (X-ray, ultraviolet/optical/infrared, radio) analysis of the relativistic tidal disruption event candidate Sw J2058+05 from 3 months to 3 yr post-discovery in order to study its properties and compare its behavior with that of
Bower, Geoffrey C.   +15 more
core   +2 more sources

Interleukin and prostaglandin status of patients with shingles depending on the severity of the disease

open access: yesPatologìâ, 2020
Aim. The aim of the work is to study the interleukin and prostaglandin status of patients with shingles depending on the severity of the disease. Materials and methods. We examined the blood of 27 patients with shingles, aged from 52 to 69 years, with
O. M. Novytskyi, I. S. Haidash
doaj   +1 more source

Amyloid proteotoxicity initiates an inflammatory response blocked by cannabinoids. [PDF]

open access: yes, 2016
The beta amyloid (Aβ) and other aggregating proteins in the brain increase with age and are frequently found within neurons. The mechanistic relationship between intracellular amyloid, aging and neurodegeneration is not, however, well understood.
Currais, Antonio   +5 more
core   +2 more sources

NSAID : Dari Analgetik-antiinflamasi ke Antineoplasi

open access: yesJournal of Dentistry Indonesia, 2015
Inflammatory mediators, such as prostaglandins and histamines can cause pain. Non steroid anti-inflammatory drugs (NSAIDs) have been indicated to reduce pain on inflammatory conditions.
Gunawan Wibisono
doaj   +1 more source

Cyclopentenone Prostaglandins: Biologically Active Lipid Mediators Targeting Inflammation

open access: yesFrontiers in Physiology, 2021
Cyclopentenone prostaglandins (cyPGs) are biologically active lipid mediators, including PGA2, PGA1, PGJ2, and its metabolites. cyPGs are essential regulators of inflammation, cell proliferation, apoptosis, angiogenesis, cell migration, and stem cell ...
Bohae Rachel Lee   +2 more
doaj   +1 more source

Role of Prostaglandins in Neuroinflammatory and Neurodegenerative Diseases

open access: yesMediators of Inflammation, 2012
Increasing data demonstrates that inflammation participates in the pathophysiology of neurodegenerative diseases. Among the different inflammatory mediators involved, prostaglandins play an important role.
Isabel Vieira de Assis Lima   +4 more
doaj   +1 more source

Home - About - Disclaimer - Privacy