Results 21 to 30 of about 277,845 (352)

The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn2+ on CatSper Ca2+ Channels in Human Sperm

Frontiers in Cell and Developmental Biology, 2021
The sperm-specific Ca2+ channel CatSper registers chemical cues that assist human sperm to fertilize the egg. Prime examples are progesterone and prostaglandin E1 that activate CatSper without involving classical nuclear and G protein-coupled receptors ...
Janice K. Jeschke, Cristina Biagioni, Tobias Schierling, Isabel Viola Wagner, Isabel Viola Wagner, Frederik Börgel, Dirk Schepmann, Andreas Schüring, Alexandra E. Kulle, Paul Martin Holterhus, Michael von Wolff, Bernhard Wünsch, Verena Nordhoff, Timo Strünker, Timo Strünker, Christoph Brenker   +15 more
doaj   +1 more source

Metformin attenuates high-fat diet induced metabolic syndrome related osteoarthritis through inhibition of prostaglandins

Frontiers in Cell and Developmental Biology, 2023
High-fat diet induces bone marrow inflammation and osteoarthritis phenotype in knee joint, but the underlying mechanisms is unknown. Here, we report that high-fat diet induces aberrant bone formation and cartilage degeneration in knee joint ...
Xiaonan Liu, Qiaoyue Guo, Qiaoyue Guo, Lei Wang, Yiru Gu, Senxiong Meng, Yuan Gu, Bin Yu   +7 more
doaj   +1 more source

The calcium-sensing receptor modulates the prostaglandin E2 pathway in intestinal inflammation

Frontiers in Pharmacology, 2023
Introduction: The prostaglandin E2 (PGE2) pathway is one of the main mediators of intestinal inflammation. As activation of the calcium-sensing receptor (CaSR) induces expression of inflammatory markers in the colon, we assessed the impact of the CaSR on
Valeriya Gushchina, Nadja Kupper, Michael Schwarzkopf, Gitta Frisch, Karina Piatek, Cornelia Aigner, Alexandra Michel, Hemma Schueffl, Luca Iamartino, Luca Iamartino, Taha Elajnaf, Taha Elajnaf, Teresa Manhardt, Andrea Vlasaty, Petra Heffeter, Marcella Bassetto, Marcella Bassetto, Enikö Kállay, Martin Schepelmann   +18 more
doaj   +1 more source

NSAID : Dari Analgetik-antiinflamasi ke Antineoplasi

Journal of Dentistry Indonesia, 2015
Inflammatory mediators, such as prostaglandins and histamines can cause pain. Non steroid anti-inflammatory drugs (NSAIDs) have been indicated to reduce pain on inflammatory conditions.
Gunawan Wibisono
doaj   +1 more source

Effect of prostaglandin analogues on central corneal thickness in patients with glaucoma: A systematic review and meta-analysis with trial sequential analysis

Indian Journal of Ophthalmology, 2022
The objective of this meta-analysis was to evaluate the effect of prostaglandin analogues (PGA) on central corneal thickness (CCT) in patients with glaucoma. Key electronic databases were searched for randomized controlled trials (RCTs) involving the CCT
Rajani Kadri, Akansha Shetty, Devika Parameshwar, Ajay A Kudva, Asha Achar, Jayaram Shetty   +5 more
doaj   +1 more source

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes.

Journal of Clinical Investigation, 2001
Virtually every organism has evolved mechanisms by which, upon stimulation, lipids are released from plasma membranes and metabolized into mediators capable of changing cellular physiology.
S. Tilley, T. Coffman, B. Koller
semanticscholar   +1 more source

Exosomes account for vesicle-mediated transcellular transport of activatable phospholipases and prostaglandins[S]

Journal of Lipid Research, 2010
Exosomes are bioactive vesicles released from multivesicular bodies (MVB) by intact cells and participate in intercellular signaling. We investigated the presence of lipid-related proteins and bioactive lipids in RBL-2H3 exosomes.
C. Subra, David Grand, Karine Laulagnier, Alexandre Stella, G. Lambeau, Michael R Paillasse, P. de Medina, B. Monsarrat, B. Perret, S. Silvente-Poirot, M. Poirot, M. Record   +11 more
semanticscholar   +1 more source

Prostaglandins for preventing postpartum haemorrhage.

Cochrane Database of Systematic Reviews, 2012
BACKGROUND Prostaglandins have mainly been used for postpartum haemorrhage (PPH) when other measures fail. Misoprostol, a new and inexpensive prostaglandin E1 analogue, has been suggested as an alternative for routine management of the third stage of ...
Özge Tunçalp, G. Hofmeyr, A. M. Gülmezoglu   +2 more
semanticscholar   +1 more source

Prostaglandins and anti-prostaglandins in pathogenesis and treatment of primary dysmenorrhea [PDF]

Гинекология, 2017
The article deals with modern theories of the pathogenesis of dysmenorrhea. A special place is given to prostaglandin, an anti-prostaglandin theory. As a therapy for dysmenorrhea, the group of prostaglandin-synthetase inhibitors is considered in detail ...
E A Mezhevitinova, V N Prilepskaya
doaj  

Celecoxib Improves Host Defense through Prostaglandin Inhibition during Histoplasma capsulatum Infection

Mediators of Inflammation, 2013
Prostaglandins act as mediators of inflammation and, similar to cytokines, function as immune modulators during innate and adaptive immune responses. Therefore, using a pharmacological inhibitor, celecoxib, we investigated the role of prostaglandins in ...
Priscilla Aparecida Tartari Pereira, Bruno Caetano Trindade, Adriana Secatto, Roberto Nicolete, Camila Peres-Buzalaf, Simone Gusmão Ramos, Ruxana Sadikot, Claudia da Silva Bitencourt, Lúcia Helena Faccioli   +8 more
doaj   +1 more source