Results 61 to 70 of about 64,031 (206)
Advanced Science, EarlyView.This work summarizes the efficacy and mechanisms of probiotics in CRC treatment, providing a comprehensive overview of various encapsulation methods such as microcapsules, hydrogels, single‐cell nanocoatings, and nanofibers for targeted probiotic delivery to inflammatory sites, with particular emphasis on the potential advantages of emerging single ...
Hao Zhong +5 more
wiley +1 more source
Advanced Science, EarlyView.Hypothalamus sympathetic norepinephrine inhibits regeneration of articular cartilage. Mechanical loading on bone during animal activity elevates PGE2 skeletal interoception to promote an anabolic renewal of the superficial membrane by downregulation of norepinephrine for articular cartilage proper thickness and integrity.
Ziyi Wang +8 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 236-248, January 2023., 2023 Chemical compositions such as protein, fat, ash, moisture, starch, vitamin B1 and mineral, as well as amino acids and fatty acids were determined in kabuli and desi chickpea species. Forty‐six types of flavonoids in Muying‐1 chickpea were analyzed with UPLC‐QqQ‐MS method.
Shiqi Xiao +3 more
wiley +1 more source
Herbal medicine in the treatment of primary dysmenorrhea
Journal of Medicinal Plants, 2015 Dysmenorrhea is called "primary" when there is no specific abnormality and "secondary" when the pain is caused by an underlying gynecological problem.
Ladan Kashani +3 more
doaj
Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat [PDF]
Journal of Pharmacology and Experimental Therapeutics 323(2):
488-498 (2007), 2007 Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-a (TNF-a) is involved in BBB injury and edema formation through a mechanism involving matrix metalloproteinase (MMP) upregulation. There is emerging evidence
arxiv
Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis
Advanced Science, EarlyView.In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li +6 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 458-469, January 2023., 2023 In this work, we demonstrated that PUM70 specifically suppressed LPS‐mediated inflammatory responses. Notably, PUM70 treatment inhibited LPS‐induced lung damage, pro‐inflammatory cytokine production, and reduced macrophage infiltration in the lungs. Mechanistically, PUM70 suppressed LPS‐induced inflammation and oxidative stress via the Nrf2/HO‐1 and ...
Fei Peng, Xin Ren, Bin Du, Yuedong Yang
wiley +1 more source
Identification of structural features in chemicals associated with cancer drug response: A systematic data-driven analysis [PDF]
arXiv, 2013 Motivation: Analysis of relationships of drug structure to biological response is key to understanding off-target and unexpected drug effects, and for developing hypotheses on how to tailor drug thera-pies. New methods are required for integrated analyses of a large number of chemical features of drugs against the corresponding genome-wide responses of
arxiv
AGING MEDICINE, EarlyView.Pogostemon cablin Benth. (PCEE) is a promising antiaging agent that inhibits ROS, decreases the senescence‐associated β‐galactosidase (SA‐β‐gal) gene, and maintains telomere length in doxorubicin‐induced 3T3‐L1 fibroblast cells. The researchers extend their gratitude to www.freepik.com for providing Figure telomer.
Teguh Santoso +6 more
wiley +1 more source
Food Science &Nutrition, Volume 11, Issue 1, Page 527-534, January 2023., 2023 Following oral administration of arthrocen supplement in post‐stroke depression model, the study recommended a novel protective effect by arthrocen on neuroinflammation due to stroke. It may play an antidepressant role through anti‐inflammatory as well as improved activity and mobility in mice‐induced stroke.
Ramin Goudarzi +5 more
wiley +1 more source