Results 101 to 110 of about 19,015,309 (380)

Mechanical Biomimetic Nanocomposites for Multidimensional Treatment of Arterial Thrombosis

Advanced Science, EarlyView.
In this study, a mechanical biomimetic nanocomposite is developed, guided by photoacoustic imaging, to achieve highly efficient and safe thrombolysis through the synergistic effects of photothermal therapy and pharmacological intervention. Most notably, the nanoparticle improves the microenvironment of arterial thrombi, marked by high shear stress and ...
Ying Li, Qi Xiang, Yan Zhang, Fuxue Luo, Yunfang Wu, Haitao Ran, Yang Cao   +6 more
wiley   +1 more source

Chemical composition of kabuli and desi chickpea (Cicer arietinum L.) cultivars grown in Xinjiang, China

Food Science &Nutrition, Volume 11, Issue 1, Page 236-248, January 2023., 2023
Chemical compositions such as protein, fat, ash, moisture, starch, vitamin B1 and mineral, as well as amino acids and fatty acids were determined in kabuli and desi chickpea species. Forty‐six types of flavonoids in Muying‐1 chickpea were analyzed with UPLC‐QqQ‐MS method.
Shiqi Xiao, Zhenglei Li, Keqiang Zhou, Yinghua Fu   +3 more
wiley   +1 more source

Effects of misoprostrol on pentylenetetrazol-induced seizures in mice Efeitos de misoprostrol sobre convulsões induzidas por pentilenotetrazol em camundongos

Arquivos de Neuro-Psiquiatria, 1997
The effects of prostaglandin E - analogue misoprostol on the susceptibility to pentilenetetrazol(PTZ) - induced seizures were examined in mice. Misoprostol (200-800 mg/kg), given subcutaneously 45 min before the subconvulsive dose of PTZ (30 mg/kg, i.p ...
Francisco das Chagas Medeiros, Maria Angelina Medeiros, Vietla Satyanarayna Rao, Eberval Gadelha Figueiredo   +3 more
doaj   +1 more source

Identification of structural features in chemicals associated with cancer drug response: A systematic data-driven analysis [PDF]

arXiv, 2013
Motivation: Analysis of relationships of drug structure to biological response is key to understanding off-target and unexpected drug effects, and for developing hypotheses on how to tailor drug thera-pies. New methods are required for integrated analyses of a large number of chemical features of drugs against the corresponding genome-wide responses of
arxiv  

Patchouli Ethanol Extract Pogostemon cablin Benth. Against Aging Profiles in Doxorubicin‐Induced 3T3‐L1 Fibroblast Cell Lines

AGING MEDICINE, EarlyView.
Pogostemon cablin Benth. (PCEE) is a promising antiaging agent that inhibits ROS, decreases the senescence‐associated β‐galactosidase (SA‐β‐gal) gene, and maintains telomere length in doxorubicin‐induced 3T3‐L1 fibroblast cells. The researchers extend their gratitude to www.freepik.com for providing Figure telomer.
Teguh Santoso, Astrid Feinisa Khairani, Muhammad Hasan Bashari, Julia Ramadhanti, Enny Rohmawati, Monika Pury Oktora, Hesti Lina Wiraswati   +6 more
wiley   +1 more source

Pyrus ussuriensis Maxim 70% ethanol eluted fraction ameliorates inflammation and oxidative stress in LPS‐induced inflammation in vitro and in vivo

Food Science &Nutrition, Volume 11, Issue 1, Page 458-469, January 2023., 2023
In this work, we demonstrated that PUM70 specifically suppressed LPS‐mediated inflammatory responses. Notably, PUM70 treatment inhibited LPS‐induced lung damage, pro‐inflammatory cytokine production, and reduced macrophage infiltration in the lungs. Mechanistically, PUM70 suppressed LPS‐induced inflammation and oxidative stress via the Nrf2/HO‐1 and ...
Fei Peng, Xin Ren, Bin Du, Yuedong Yang
wiley   +1 more source

A neurotoxicidade da Cannabis sativa e suas repercussões sobre a morfologia do tecido cerebral

ABCS Health Sciences, 2014
Para a compreensão das repercussões psicológicas e comportamentais verificadas em usuários de Cannabis sativa, experimentos têm sido desenvolvidos analisando a relação entre a intensidade do uso da droga e biomarcadores de lesão e inflamação. Dessa forma,
Bárbara da Silva Santos, Marcelo Coertjens   +1 more
doaj   +1 more source

Integrating Aggregate Materials and Machine Learning Algorithms: Advancing Detection of Pathogen‐Derived Extracellular Vesicles

Aggregate, EarlyView.
Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai, Yun Su, Cong Hu, Zehong Peng, Wei Xue, Liang Dong, Tony Y. Hu   +6 more
wiley   +1 more source

Beneficial effects of arthrocen on neuroinflammation and behavior like depression in stroke in a murine model

Food Science &Nutrition, Volume 11, Issue 1, Page 527-534, January 2023., 2023
Following oral administration of arthrocen supplement in post‐stroke depression model, the study recommended a novel protective effect by arthrocen on neuroinflammation due to stroke. It may play an antidepressant role through anti‐inflammatory as well as improved activity and mobility in mice‐induced stroke.
Ramin Goudarzi, Golnaz Zamanian, Zahra Seyyedian, Partow Mirzaee Saffari, Ahmad Reza Dehpour, Alireza Partoazar   +5 more
wiley   +1 more source

Anti-Inflammatory Cembrane-Type Diterpenoids and Prostaglandins from Soft Coral Lobophytum sarcophytoides

Marine Drugs, 2019
Two new cembrane-type diterpenoids, lobophytins A (1) and B (3), and four new prostaglandins, (5E)-PGB2 (10), (5E)-13,14-dihydro-PGB2 (11), 13,14-dihydro-PGB2 (12) and 13,14-dihydro-PGB2-Me (13), together with ten known compounds were isolated from the ...
Hongjie Shen, Xiaowan Liu, Minghua Jiang, Guangyuan Luo, Zhenger Wu, Bin Chen, Jing Li, Lan Liu, Senhua Chen   +8 more
doaj   +1 more source