Results 281 to 290 of about 74,984 (316)
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Depression, immunocompetence, and prostaglandins of the E series
Psychiatry Research, 1986Plasma prostaglandin E1 and E2, and quantitative and qualitative measures of immune function, were determined in depressed patients and healthy controls. Prostaglandin E2 was significantly elevated in the depressed group, and prostaglandin E1 showed a trend in the same direction.
J R, Calabrese +7 more
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The immunomodulatory actions of E-type prostaglandins
Expert Opinion on Investigational Drugs, 1997Prostaglandins (PGs) have been recognised as modulators of immune responses. This has been proved by both in vitro studies and from observations in animals and humans. Administration of prostaglandins for therapeutic purposes, however, has been hampered by their limited bioavailability and their pleiotropic effects, with resultant toxicological profile.
G, De Vries, A, McLaughlin, J, Rhodes
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The content of prostaglandin E and prostaglandin F2α in the exudate of carrageenin granuloma of rats
Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 19761. Granuloma was made by the subcutaneous injection of 2% carrageenin solution on the dorsum of male rats. Eight, 16, 24 and 72 h after the injection. the exudate from each rat granuloma was withdrawn and extracted for rpstaglandins. 2. Extracted prostaglandins were separated prostaglandin E and prostaglandin F group by silicic acid mini-column ...
K, Ohuchi, H, Sato, S, Tsurufuji
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Biochemical and Biophysical Research Communications, 1997
Prostaglandin (PG) E synthase was found to be widely distributed in the microsomal fractions of rat organs. Among them, an extremely high activity was seen in the deferent duct (112 nmol/min x mg) and other genital accessory organs (10-20 nmol/min x mg). In non-genital organs, the kidney had the highest activity (8 nmol/min x mg).
K, Watanabe +3 more
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Prostaglandin (PG) E synthase was found to be widely distributed in the microsomal fractions of rat organs. Among them, an extremely high activity was seen in the deferent duct (112 nmol/min x mg) and other genital accessory organs (10-20 nmol/min x mg). In non-genital organs, the kidney had the highest activity (8 nmol/min x mg).
K, Watanabe +3 more
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American Review of Respiratory Disease, 1991
Abstract Prostaglandin E (PGE), a cyclooxygenase metabolite normally present in high concentrations in respiratory epithelial lining fluid (ELF), is capable of suppressing mesenchymal cell proliferation mediated by polypeptide-derived growth factors.
Z, Borok +7 more
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Abstract Prostaglandin E (PGE), a cyclooxygenase metabolite normally present in high concentrations in respiratory epithelial lining fluid (ELF), is capable of suppressing mesenchymal cell proliferation mediated by polypeptide-derived growth factors.
Z, Borok +7 more
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Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism, 1979
Abstract The reduction of the glutathione conjugate of prostaglandin A1 by avian prostaglandin E 9-ketoreductase occurs at a faster rate than reduction of its presumed natural substrates, prostaglandin E1 or E2.
Lauren M. Cagen, John J. Pisano
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Abstract The reduction of the glutathione conjugate of prostaglandin A1 by avian prostaglandin E 9-ketoreductase occurs at a faster rate than reduction of its presumed natural substrates, prostaglandin E1 or E2.
Lauren M. Cagen, John J. Pisano
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Prostaglandin E antagonist activity of 11,15-bisdeoxy prostaglandin E1 and congeners
Prostaglandins, 1977d,l-11, 15-bisdeoxy PGE1 and certain of its congeners were shown to inhibit gerbil colon contractions induced by l-PGE1. While some of these compounds were selectively antagonistic of PGE1-induced contractions, others additionally inhibited the gerbil colon agonist activities of l-PGE2alpha and acetylcholine. The PGE1 inhibitory activity was apparently
E L, Tolman, R, Partridge, E T, Barris
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Prostaglandin E and cancer Growth
Cancer Immunology, Immunotherapy, 1980This paper reviews the evidence linking prostaglandin E (PGE) with the growth of neoplastic tissue. PGE 2 is present in high concentrations in many natural and experimentally produced cancers. The immunosuppressive effect of some tumors in mice is due at least in part to a prostaglandin mechanism.
J. S. Goodwin, G. Husby, R. C. Williams
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Prostaglandins and Inflammation
Arteriosclerosis, Thrombosis, and Vascular Biology, 2011Emanuela Ricciotti, Garret A Fitzgerald
exaly