Results 261 to 270 of about 141,844 (309)

Two Types of Microsomal Prostaglandin E Synthase: Glutathione-Dependent and -Independent Prostaglandin E Synthases

Biochemical and Biophysical Research Communications, 1997
Prostaglandin (PG) E synthase was found to be widely distributed in the microsomal fractions of rat organs. Among them, an extremely high activity was seen in the deferent duct (112 nmol/min x mg) and other genital accessory organs (10-20 nmol/min x mg). In non-genital organs, the kidney had the highest activity (8 nmol/min x mg).
K, Watanabe, K, Kurihara, Y, Tokunaga, O, Hayaishi   +3 more
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Pharmacocavernometry with Prostaglandin E(1)

European Urology, 1993
The aim of this study was to define the normal response of cavernometry parameters with high-dose pharmacostimulation, to investigate repeatability of the method and to find out the incidence of cavernovenous leakage in impotence. 82 consecutive impotent patients and 10 potent control subjects underwent pharmacocavernometry with 40 micrograms of ...
H O, Nisén, M L, Ruutu
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19-HydroxyIated E prostaglandins as the major prostaglandins of human semen

Nature, 1974
ALMOST 30 years after the initial discovery of the prostaglandins, Bergstrom et al., succeeded in isolating and identifying prostaglandins (PGs) E1, E2, F1α and F2α from sources including human semen1. It was subsequently claimed2 that the 19-hydroxy derivatives of prostaglandins A and B were also present. These compounds were later found at an average
P L, Taylor, R W, Kelly
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Role of seminal prostaglandins in male fertility. I. Relationship of prostaglandin E and 19-OH prostaglandin E with seminal parameters

Journal of Endocrinological Investigation, 1980
Prostaglandin (PG) E and 19-OH PGE, now considered to be the most important of the human seminal prostaglandins, were assayed in infertile and normal men. In the 15 volunteers PGE and 19-OH PGE levels were 23-89 microgram/ml, respectively. In the 4 groups of infertile patients in whom either PGE or 19-OH PGE levels were increased or decreased with ...
A, Isidori, D, Conte, G, Laguzzi, P, Giovenco, F, Dondero   +4 more
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Prostaglandin E antagonist activity of 11,15-bisdeoxy prostaglandin E1 and congeners

Prostaglandins, 1977
d,l-11, 15-bisdeoxy PGE1 and certain of its congeners were shown to inhibit gerbil colon contractions induced by l-PGE1. While some of these compounds were selectively antagonistic of PGE1-induced contractions, others additionally inhibited the gerbil colon agonist activities of l-PGE2alpha and acetylcholine. The PGE1 inhibitory activity was apparently
E L, Tolman, R, Partridge, E T, Barris
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Prostaglandin E and cancer Growth

Cancer Immunology, Immunotherapy, 1980
This paper reviews the evidence linking prostaglandin E (PGE) with the growth of neoplastic tissue. PGE 2 is present in high concentrations in many natural and experimentally produced cancers. The immunosuppressive effect of some tumors in mice is due at least in part to a prostaglandin mechanism.
J. S. Goodwin, G. Husby, R. C. Williams
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ChemInform Abstract: TOTAL SYNTHESIS OF PROSTAGLANDINS PART 7, ASYMMETRIC TOTAL SYNTHESIS OF (‐)‐PROSTAGLANDIN E(1) AND (‐)‐PROSTAGLANDIN E(2)

Chemischer Informationsdienst, 1975
AbstractMikrobiologische asymm. Reduktion der Triketone (I) mit Dipodascus uninucleatus liefert die (4R)‐Alkohole (II).
CHARLES J. SIH, J. B. HEATHER, RATTAN SOOD, PHILIP PRICE, GEORGE PERUZZOTTI, L. F. HSU LEE, S. S. LEE   +6 more
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Prostaglandin E₂inhibits fibroblast chemotaxis

American Journal of Physiology-Lung Cellular and Molecular Physiology, 2001
Fibroblasts are the major source of extracellular connective tissue matrix, and the recruitment, accumulation, and stimulation of these cells are thought to play important roles in both normal healing and the development of fibrosis. Prostaglandin E2(PGE2) can inhibit this process by blocking fibroblast proliferation and collagen production. The aim of
T, Kohyama, R F, Ertl, V, Valenti, J, Spurzem, M, Kawamoto, Y, Nakamura, T, Veys, L, Allegra, D, Romberger, S I, Rennard   +9 more
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ChemInform Abstract: STEREOSELECTIVE REDUCTION OF PROSTAGLANDINS E TO PROSTAGLANDINS F

Chemischer Informationsdienst, 1980
AbstractDie Prostaglandine E (I) gehen bei der Reduktion mit Li in Tetrahydrofuran und flüssigem Ammoniak in die Prostaglandine Fß(II) über.
V. I. MEL'NIKOVA, K. K. PIVNITSKII
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Prostaglandin E receptors

Journal of Lipid Mediators and Cell Signalling, 1995
M, Negishi, Y, Sugimoto, A, Ichikawa
openaire   +2 more sources