Results 271 to 280 of about 74,984 (316)

Prostaglandin E2-induced inflammation: Relevance of prostaglandin E receptors

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 2015
Prostaglandin E2 (PGE2) is one of the most typical lipid mediators produced from arachidonic acid (AA) by cyclooxygenase (COX) as the rate-limiting enzyme, and acts on four kinds of receptor subtypes (EP1-EP4) to elicit its diverse actions including pyrexia, pain sensation, and inflammation.
Kohichi, Kawahara, Hirofumi, Hohjoh, Tomoaki, Inazumi, Soken, Tsuchiya, Yukihiko, Sugimoto   +4 more
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19-HydroxyIated E prostaglandins as the major prostaglandins of human semen

Nature, 1974
ALMOST 30 years after the initial discovery of the prostaglandins, Bergstrom et al., succeeded in isolating and identifying prostaglandins (PGs) E1, E2, F1α and F2α from sources including human semen1. It was subsequently claimed2 that the 19-hydroxy derivatives of prostaglandins A and B were also present. These compounds were later found at an average
P L, Taylor, R W, Kelly
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Role of seminal prostaglandins in male fertility. I. Relationship of prostaglandin E and 19-OH prostaglandin E with seminal parameters

Journal of Endocrinological Investigation, 1980
Prostaglandin (PG) E and 19-OH PGE, now considered to be the most important of the human seminal prostaglandins, were assayed in infertile and normal men. In the 15 volunteers PGE and 19-OH PGE levels were 23-89 microgram/ml, respectively. In the 4 groups of infertile patients in whom either PGE or 19-OH PGE levels were increased or decreased with ...
A, Isidori, D, Conte, G, Laguzzi, P, Giovenco, F, Dondero   +4 more
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Pharmacocavernometry with Prostaglandin E(1)

European Urology, 1993
The aim of this study was to define the normal response of cavernometry parameters with high-dose pharmacostimulation, to investigate repeatability of the method and to find out the incidence of cavernovenous leakage in impotence. 82 consecutive impotent patients and 10 potent control subjects underwent pharmacocavernometry with 40 micrograms of ...
H O, Nisén, M L, Ruutu
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Stability of prostaglandin E compounds in solution

Lipids, 1973
AbstractIn the present paper the stability of prostaglandins E1, E2, and E3 has been studied in two types of solvents: (a) solvents in which they can be used in clinical trials and (b) solvents which are commonly used for their isolation from biological systems.
K C, Srivastava, J, Clausen
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Difference in Haemodynamic Response to Prostaglandins A and E

Nature, 1971
PROSTAGLANDINS A and E are vasodepressor substances, the effect of which has been attributed to direct vasodilator action on peripheral arteriolar smooth muscle1–7. The mechanism of the hypotensive effect of the two prostaglandins may not, however, be identical.
H, Kannegiesser, J B, Lee
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Prostaglandin E in peptic ulcer disease

Prostaglandins, 1974
Abstract Prostaglandin E 1 and E 2 inhibit gastric secretion in vivo and in vitro under a variety of conditions. It is not known whether these compounds may play a role in normal gastric secretory physiology or in the pathophysiology of peptic ulcer disease.
J G, Hinsdale, J J, Engel, D E, Wilson
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Prostaglandin E synthase in the pathophysiology of arthritis

Fundamental & Clinical Pharmacology, 2005
AbstractProstaglandin E synthase (PGES) is a recently identified terminal enzyme that acts downstream of cyclooxygenase and catalyzes the conversion of prostaglandin (PG) H2 to PGE2. At least three isozymes have been cloned so far, which are called membrane‐associated PGES (mPGES)‐1, mPGES‐2, and cytosolic PGES.
Fumiaki, Kojima, Soichiro, Kato, Shinichi, Kawai   +2 more
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Stability of E-Type Prostaglandins in Triacetin

Journal of Pharmaceutical Sciences, 1979
A drug delivery system for E-type prostaglandins is described. In this system, consisting of drug dissolved in triacetin and filled into soft gelatin capsules, normally unstable prostaglandins show excellent stability at room temperature.
S H, Yalkowsky, T J, Roseman
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Measurement of prostaglandin E in crevicular fluid

Journal of Clinical Periodontology, 1981
Abstract A method for the detection of prostaglandin E (PGE) in crevicular fluid has been developed which provides a sensitive, noninvasive technique for measurement of local concentrations of this mediator of inflammation. Assay sensitivity sufficient for the detection of 4 picograms of PGE2; was achieved by utilizing a high‐affinity anti‐PGE2 ...
S, Offenbacher, D H, Farr, J M, Goodson
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