Results 1 to 10 of about 257,390 (240)

Inflamm-aging and arachadonic acid metabolite differences with stage of tendon disease. [PDF]

PLoS ONE, 2012
The contribution of inflammation to the pathogenesis of tendinopathy and high prevalence of re-injury is not well established, although recent evidence suggests involvement of prostaglandins.
Stephanie Georgina Dakin, Jayesh Dudhia, Natalie Jayne Werling, Dirk Werling, Dilkush Robert Ephrem Abayasekara, Roger Kenneth Whealands Smith   +5 more
doaj   +1 more source

Aspirin treatment of mice infected with Trypanosoma cruzi and implications for the pathogenesis of Chagas disease. [PDF]

PLoS ONE, 2011
Chagas disease, caused by infection with Trypanosoma cruzi, is an important cause of cardiovascular disease. It is increasingly clear that parasite-derived prostaglandins potently modulate host response and disease progression.
Shankar Mukherjee, Fabiana S Machado, Huang Huang, Helieh S Oz, Linda A Jelicks, Cibele M Prado, Wade Koba, Eugene J Fine, Dazhi Zhao, Stephen M Factor, J Elias Collado, Louis M Weiss, Herbert B Tanowitz, Anthony W Ashton   +13 more
doaj   +1 more source

Prostaglandins F₂α and E₂ in rat placenta and fetal membrane: a comprehensive immunohistochemistry of their synthetic enzymes and <i>in vivo</i> tissue levels during normal pregnancy

Journal of Veterinary Medical Science, 2021
We determined a comprehensive immunohistochemistry of putative isoforms of enzymes for prostaglandin (PG) F2α and PGE2 biosynthesis and these PGs levels in placenta and fetal membrane of normal pregnant rats in vivo. Placenta and fetal membrane showed positive immunoreactions for phospholipase A2 group 4A, but not group 2A, and cyclooxygenase (COX)-1 ...
Shiro Kurusu, Ryota Terashima, Mitsumori Kawaminami, Hironori Satoh   +3 more
openaire   +4 more sources

EFFECT OF VERAPAMIL ON THE PULMONARY VASOCONSTRICTOR ACTION OF PROSTAGLANDIN F_2α AND A SYNTHETIC PGH₂ ANALOGUE [PDF]

British Journal of Pharmacology, 1981
The vasopressor response to prostaglandin F2α (PGF2α) and to ((15S)‐hydroxy‐11α, 9α‐(epoxymethano)‐prosta‐5Z, 13E‐dienoic acid) (U‐46619) in the canine isolated lung lobe was significantly attenuated following the administration of verapamil. The pressor response to arachidonic acid (AA) was not affected by the presence of verapamil.
Peter W. Ramwell, Peter A. Kot, T M Fitzpatrick, Allan D. Angerio, John C. Rose   +4 more
openaire   +3 more sources

Avaliação econômica das associações fixas de prostaglandina/prostamida e timolol no tratamento do glaucoma e da hipertensão ocular Economic evaluation of Prostaglandin/Prostamide and timolol fixed combinations in the treatment of glaucoma and ocular hypertension

Revista Brasileira de Oftalmologia, 2010
OBJETIVO: Avaliar o custo ao final de 5 anos, a efetividade e a relação custo-efetividade das associações fixas de prostaglandina ou prostamida com timolol 0,5% para o tratamento do glaucoma e da hipertensão ocular no Estado de Minas Gerais, Brasil ...
Ricardo Augusto Paletta Guedes, Vanessa Maria Paletta Guedes, Julia Linhares Borges, Alfredo Chaoubah   +3 more
doaj   +1 more source

Functional characterization of synthetic leukotriene B and its stereochemical isomers. [PDF]

, 1981
Leukotriene B (LTB), a potent lipid chemotactic factor for neutrophils, is 5S,12R-dihydroxy-6,14-cis,8,10-trans-eicosatetraenoic acid (Fig 1), based upon direct comparison of natural LTB with synthetic 5S,12R-dihydroxy-6,8,10,14-eicosatetraenoic acid (5 ...
Austen, K, Corey, E, Drazen, J, Goetzl, Edward, Lewis, R, Soter, N   +5 more
core   +1 more source

Modeling of biological doses and mechanical effects on bone transduction [PDF]

Journal of Theoretical Biology 274, 1 (2011) 36-42, 2011
Shear stress, hormones like parathyroid and mineral elements like calcium mediate the amplitude of stimulus signal which affects the rate of bone remodeling. The current study investigates the theoretical effects of different metabolic doses in stimulus signal level on bone.
arxiv   +1 more source

Implementation of synthetic fast-ion loss detector and imaging heavy ion beam probe diagnostics in the 3D hybrid kinetic-MHD code MEGA [PDF]

Review of Scientific Instruments 92, 043558 (2021), 2022
A synthetic Fast-Ion Loss Detector (FILD) and an imaging Heavy Ion Beam Probe (i-HIBP) have been implemented in the 3D hybrid kinetic-magnetohydrodynamic code MEGA. First synthetic measurements from these two diagnostics have been obtained for neutral beam injection (NBI) driven Alfv\'en Eigenmode (AE) simulated with MEGA. The synthetic fast-ion losses
arxiv   +1 more source

Effect of oleic acid supplementation on prostaglandin production in maternal endometrial and fetal allantochorion cells isolated from late gestation ewes [PDF]

, 2015
Elevated circulating non-esterified fatty acids including oleic acid (OA) are associated with many pregnancy related complications. Prostaglandins (PGs) play crucial roles during parturition.
Aardema, Alves, Arsic, Asselin, Carluccio, Catov, Challis, Chen, Cheng, Cheng, Cheng, Cheng, Cherny, Chu, Crane, D.C. Wathes, D.R.E. Abayasekara, Flynn, Goncalves, Guillou, Herath, Jabbour, Karsch, Kim, Klein, Lamont, Lee, Leung, Lewis, Lunn, M. Elmes, Nielsen, Noble, Poyser, Reddy, Rimoldi, Robinson, S. Kirkup, Sharp, Smith, Smith, Thorburn, Villa, Wang, Wathes, Wendell, Whittle, Witkin, Z. Cheng, Zhang   +49 more
core   +1 more source

Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice [PDF]

, 2007
Cyclooxygenase-2 (COX-2)-dependent prostaglandin (PG) E2 synthesis in the spinal cord plays a major role in the development of inflammatory hyperalgesia and allodynia. Microsomal PGE2 synthase-1 (mPGES-1) isomerizes COX-2-derived PGH2 to PGE2.
Angioni, Carlo Federico, Becker, Wiebke, Brenneis, Christian, Coste, Ovidiu, Geisslinger, Gerd, Nusing, Rolf M., Popp, Laura, Schmidt, Ronald, Scholich, Klaus   +8 more
core   +1 more source