Results 11 to 20 of about 187,667 (75)

Wide therapeutic time window for nimesulide neuroprotection in a model of transient focal cerebral ischemia in the rat [PDF]

Brain Research 1007(1-2): 98-108 (2004), 2007
Results from several studies indicate that cyclooxygenase-2 (COX-2) is involved in ischemic brain injury. The purpose of this study was to evaluate the neuroprotective effects of the selective COX-2 inhibitor nimesulide on cerebral infarction and neurological deficits in a standardized model of transient focal cerebral ischemia in rats.
arxiv  

Cyclooxygenase Inhibition Limits Blood-Brain Barrier Disruption following Intracerebral Injection of Tumor Necrosis Factor-alpha in the Rat [PDF]

Journal of Pharmacology and Experimental Therapeutics 323(2): 488-498 (2007), 2007
Increased permeability of the blood-brain barrier (BBB) is important in neurological disorders. Neuroinflammation is associated with increased BBB breakdown and brain injury. Tumor necrosis factor-a (TNF-a) is involved in BBB injury and edema formation through a mechanism involving matrix metalloproteinase (MMP) upregulation. There is emerging evidence
arxiv  

Identification of structural features in chemicals associated with cancer drug response: A systematic data-driven analysis [PDF]

arXiv, 2013
Motivation: Analysis of relationships of drug structure to biological response is key to understanding off-target and unexpected drug effects, and for developing hypotheses on how to tailor drug thera-pies. New methods are required for integrated analyses of a large number of chemical features of drugs against the corresponding genome-wide responses of
arxiv  

Pseudo-Anosov extensions and degree one maps between hyperbolic surface bundles [PDF]

arXiv, 2005
Let $F',F$ be any two closed orientable surfaces of genus $g'>g\ge 1$, and $f:F\to F$ be any pseudo-Anosov map. Then we can "extend" $f$ to be a pseudo-Anosov map $f':F'\to F'$ so that there is a fiber preserving degree one map $M(F',f')\to M(F,f)$ between the hyperbolic surface bundles.
arxiv  

Quantum Certificate Complexity [PDF]

arXiv, 2002
Given a Boolean function f, we study two natural generalizations of the certificate complexity C(f): the randomized certificate complexity RC(f) and the quantum certificate complexity QC(f). Using Ambainis' adversary method, we exactly characterize QC(f) as the square root of RC(f). We then use this result to prove the new relation R0(f) = O(Q2(f)^2 Q0(
arxiv  

Invariants of plane curve singularities and Plücker formulas in positive characteristic [PDF]

arXiv, 2014
We study classical invariants for plane curve singularities $f\in K[[x,y]]$, $K$ an algebraically closed field of characteristic $p\geq 0$: Milnor number, delta invariant, kappa invariant and multiplicity. It is known, in characteristic zero, that $\mu(f)=2\delta(f)-r(f)+1$ and that $\kappa(f)=2\delta(f)-r(f)+\mathrm{mt}(f)$.
arxiv  

Formule de Plancherel sur $GL_n \times GL_n \backslash GL_{2n}$ [PDF]

arXiv, 2019
Let $F$ be a non archimedian local field and $H_n(F)$ the Shalika subgroup of $GL_{2n}(F)$. We prove an explicit Plancherel formula for $H_n(F) \backslash GL_{2n}(F)$ using the theory of Jacquet-Shalika of zeta functions and we deduce Plancherel decompositions for $H_n(F) \backslash GL_{2n}(F)$ and $GL_{n}(F) \times GL_{n}(F) \backslash GL_{2n}(F)$.
arxiv  

Towards Better Separation between Deterministic and Randomized Query Complexity [PDF]

arXiv, 2015
We show that there exists a Boolean function $F$ which observes the following separations among deterministic query complexity $(D(F))$, randomized zero error query complexity $(R_0(F))$ and randomized one-sided error query complexity $(R_1(F))$: $R_1(F) = \widetilde{O}(\sqrt{D(F)})$ and $R_0(F)=\widetilde{O}(D(F))^{3/4}$.
arxiv  

A COMPARISON OF THE ACTIONS OF PROSTAGLANDINS F_2a AND E₁ ON SMOOTH MUSCLE [PDF]

, 1965
E. W. HORTON, I H Main
openalex   +1 more source

New extensions for a theorem by Mocanu [PDF]

arXiv, 2013
For analytic functions f(z) in the open unit disk U with f(0)=f'(0)-1=f"(0)=0, P. T. Mocanu (Mathematica (Cluj), 42(2000)) has considered some sufficient arguments of f'(z)+zf"(z) for |\arg(zf'(z)/f(z))|<\pi\mu/2. The object of the present paper is to discuss those probrems for f(z) with f"(0)=f"'(0)=...=f^{(n)}(0)=0 and f^{(n+1)}(0) \ne 0.
arxiv