Results 211 to 220 of about 233,415 (250)
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PROSTATE-SPECIFIC ANTIGEN DENSITY
Urologic Clinics of North America, 1997Nearly 20 years have passed since PSA was definitively identified. Throughout this period, its clinical application as a tumor marker has expanded significantly. Today, besides monitoring prostate cancer therapy, PSA is being used extensively in mass screening programs for early detection of adenocarcinoma of the prostate and has become the most ...
M C, Beduschi, J E, Oesterling
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Prostate-specific membrane antigen
The Prostate, 1997In an effort to discover new prostate-specific antigens (PSAs) to enhance our understanding of the functions and behavior of the prostate and the complex processes involved in prostate tumor progression, the structure and function of the PSM antigen has been elucidated.The PSM antigen was recognized using the 7E11-C5.3 monoclonal antibody, generated ...
W R, Fair, R S, Israeli, W D, Heston
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New England Journal of Medicine, 1987
After half a century of clinical application, the usefulness of prostatic acid phosphatase (PAP) as a marker for carcinoma of the prostate is being challenged. Historically the first of the "serum markers" for the presence of a human cancer,1 acid phosphatase is still measured in clinical laboratories all over the world.
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After half a century of clinical application, the usefulness of prostatic acid phosphatase (PAP) as a marker for carcinoma of the prostate is being challenged. Historically the first of the "serum markers" for the presence of a human cancer,1 acid phosphatase is still measured in clinical laboratories all over the world.
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Deutsche medizinische Wochenschrift (1946), 1995
Prostate specific antigen (PSA) is a 34 000 Da molecular weight glycoprotein found exclusively in the prostate, prostatic fluid and seminal plasma.
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Prostate specific antigen (PSA) is a 34 000 Da molecular weight glycoprotein found exclusively in the prostate, prostatic fluid and seminal plasma.
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1994
PSA is a 34-kDa 240-amino-acid glycoprotein produced exclusively by prostatic epithelial cells. PSA is a serine protease, is a member of the kallikrein gene family, and has a high sequence homology with human glandular kallikrein. It has chymotrypsin-, trypsin-, and esterase-like activities.
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PSA is a 34-kDa 240-amino-acid glycoprotein produced exclusively by prostatic epithelial cells. PSA is a serine protease, is a member of the kallikrein gene family, and has a high sequence homology with human glandular kallikrein. It has chymotrypsin-, trypsin-, and esterase-like activities.
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Australian family physician, 2012
This article forms part of our 'Tests and results' series for 2011 which aims to provide information about common tests that general practitioners order regularly. It considers areas such as indications, what to tell the patient, what the test can and cannot tell you, and interpretation of results.
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This article forms part of our 'Tests and results' series for 2011 which aims to provide information about common tests that general practitioners order regularly. It considers areas such as indications, what to tell the patient, what the test can and cannot tell you, and interpretation of results.
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Biology of Prostate-Specific Antigen
Journal of Clinical Oncology, 2003Prostate-specific antigen (PSA) is an androgen-regulated serine protease produced by both prostate epithelial cells and prostate cancer (PCa) and is the most commonly used serum marker for cancer. It is a member of the tissue kallikrein family, some of the members of which are also prostate specific.
Steven P, Balk +2 more
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Home Health Care Management & Practice, 2015
The discovery of the prostate specific antigen (PSA) was a landmark achievement of the 20th century according to the American Cancer Society. As a result of this discovery, the PSA screening test was developed. Over the past few years, the mounting controversy over the specificity of this test led to revisions of the screening guidelines by several ...
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The discovery of the prostate specific antigen (PSA) was a landmark achievement of the 20th century according to the American Cancer Society. As a result of this discovery, the PSA screening test was developed. Over the past few years, the mounting controversy over the specificity of this test led to revisions of the screening guidelines by several ...
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The prostate-specific antigen test
Expert Opinion on Medical Diagnostics, 2013Before the 1980s, prostate cancer (PC) was considered a deadly disease. The mortality-incidence ratio showed that 1 out of each 2 - 3 PC patients died of this disease. On the other hand, autopsy studies have shown that latent PC is common in middle-aged men.
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