Results 221 to 230 of about 8,268,208 (290)

Predictive Value of [-2]proPSA-Related Indices for Prostate Cancer Detection Years Before Prostate-Specific Antigen Elevation: Insights From a Five-Year Longitudinal Screening Cohort. [PDF]

Prostate
Sekine Y, Fujizuka Y, Nakazawa S, Tsuji Y, Ohtsu A, Miyazawa Y, Arai S, Nomura M, Koike H, Matsui H, Ito K, Suzuki K.   +11 more
europepmc   +1 more source

Mass Spectrometry Insights Into Post‐Translational Modifications in Extracellular Vesicles

Mass Spectrometry Reviews, EarlyView.
ABSTRACT Extracellular vesicles (EVs) are membrane‐enclosed structures secreted by virtually all living cells, serving as essential mediators of intercellular communication in both physiological and pathological processes. There is growing interest in their potential applications as biomarkers, therapeutic targets, and drug delivery systems, which ...
Dávid Virág, Krisztián Márk Karvaly, Alexandra Molnár, Mirjam Balbisi, Júlia Németh, Lilla Turiák   +5 more
wiley   +1 more source

[Prostate specific antigen].

Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1990
E, Paus, L, Theodorsen
openaire   +1 more source

Hypoxia‐Induced ADAM23 Drives Neuron–Tumor Crosstalk and Therapeutic Resistance in Hepatocellular Carcinoma

Molecular Carcinogenesis, EarlyView.
ABSTRACT Hypoxia and nutrient deprivation are fundamental drivers of tumor aggressiveness and therapeutic resistance in hepatocellular carcinoma (HCC). While the involvement of neural components in the tumor microenvironment (TME) is increasingly recognized, the molecular transducers linking metabolic stress to neuron–tumor crosstalk remain elusive ...
Taehyun Park, Soeun Kim, Hyunjung Cho, Johyeon Nam, Dayoung Choi, Misu Lee   +5 more
wiley   +1 more source

Abnormal Flagging of Prostate Specific Antigen Screening Tests: A Regression Discontinuity Design. [PDF]

J Gen Intern Med
Lewicki P, Jiang R, Radhakrishnan A, Schipper M, Morgan T, Stensland K.   +5 more
europepmc   +1 more source

Prevention of Early Onset of Breast Cancer With Ashwagandha

Molecular Carcinogenesis, EarlyView.
ABSTRACT Prevention of breast cancer is feasible because many risk factors for this malignancy are known (e.g., family history, reproductive factors, etc.). Medicinal plants and/or their bioactive phytochemicals are attractive for the prevention of early onset of breast cancer due to their generally favorable safety profile.
Eun‐Ryeong Hahm, Su‐Hyeong Kim, Shivendra V. Singh   +2 more
wiley   +1 more source

The Complementary Roles of the Prostate Health Index and Multiparametric Magnetic Resonance Imaging in Optimizing the Detection of Clinically Significant Prostate Cancer in Patients With Prostate-Specific Antigen Levels Below 10 Ng/mL. [PDF]

Int J Urol
Sekine Y, Arai G, Kito H, Sugimoto M, Shiota M, Hasumi H, Ito K, Kobori Y, Nakada T, Kato T, Yokomizo A, Ito Y, Suzuki K, Kaji Y.   +13 more
europepmc   +1 more source

Artificial Intelligence for Identifying Tumor‐Reactive CD8+ T Cells: Biological Principles, Computational Advances, and Future Directions

Med Research, EarlyView.
This review details a three‐stage paradigm shift for tumor‐reactive CD8+ T‐cell identification: decoding transcriptomic states, deciphering clonal functional efficacy, and molecular‐level therapeutic TCR design. Addressing translational hurdles and generative AI “scientific blind spots”—such as missing catch bonds—we present a visionary roadmap.
Chao Yang, Yingying Sun, Yan Zhang, Yifen Shi, Zhiwen Shi   +4 more
wiley   +1 more source

Additional predictive value of systemic inflammation indices beyond prostate specific antigen density for clinically significant prostate cancer. [PDF]

BMC Urol
Sulhan H, Kalyenci B.
europepmc   +1 more source

AI‐Driven Rational Design of Nanotherapeutics for Pancreatic Ductal Adenocarcinoma

Medicinal Research Reviews, EarlyView.
ABSTRACT Pancreatic ductal adenocarcinoma (PDAC) remains a formidable malignancy characterized by late diagnosis, high recurrence rates, and pronounced chemoresistance. While nanoparticle‐based drug delivery systems (NDDS) offer theoretical advantages over conventional therapies, their clinical translation in PDAC has been severely limited.
Seohyun Choo, Kaeun Chae, Jueun Lee, Inseon Kim, Seunghun S. Lee   +4 more
wiley   +1 more source